Enantioseparation of palonosetron hydrochloride by micellar electrokinetic chromatography with sodium cholate as chiral selector

2006 ◽  
Vol 1132 (1-2) ◽  
pp. 333-336 ◽  
Author(s):  
Kan Tian ◽  
Hongli Chen ◽  
Jianghong Tang ◽  
Xingguo Chen ◽  
Zhide Hu
Keyword(s):  
Micellar Electrokinetic Chromatography ◽  
Sodium Cholate ◽  
Chiral Selector ◽  
Electrokinetic Chromatography

PolysodiumN-Undecanoyl-l-leucylvalinate:  A Versatile Chiral Selector for Micellar Electrokinetic Chromatography

2003 ◽  
Vol 75 (3) ◽  
pp. 379-387 ◽  
Author(s):  
Shahab A. Shamsi ◽  
Bertha C. Valle ◽  
Fereshteh Billiot ◽  
Isiah M. Warner
Keyword(s):  
Micellar Electrokinetic Chromatography ◽  
Chiral Selector ◽  
Electrokinetic Chromatography

scholarly journals Enantiomeric and Isomeric Separation of Pesticides by Cyclodextrin-Modified Micellar Electrokinetic Chromatography

1999 ◽  
Vol 82 (6) ◽  
pp. 1550-1561 ◽  
Author(s):  
Damian Shea ◽  
Kumar V Penmetsa ◽  
Ross B Leidy
Keyword(s):  
Capillary Electrophoresis ◽  
Water Samples ◽  
Micellar Electrokinetic Chromatography ◽  
Detection Limits ◽  
Sodium Cholate ◽  
Electrokinetic Chromatography ◽  
Buffer Analysis

Abstract Cyclodextrin-modified micellar electrokinetic chromatography was applied successfully to the enantiomeric and isomeric separation of 7 commonly used pesticides (propiconazole, bioallethrin, fenpropathrin, phenothrin, bitertanol, triadimenol, and dimethomorph). Commercially available surfactants used alone or in combination with cyclodextrins were evaluated for separation of the enantiomers/isomers of the 7 pesticides. The enan-tiomers/isomers of the pesticides used in this study were baseline resolved with resolutions of ≥1.5. The resolution was found to depend on the type of surfactant and cyclodextrin employed in the running buffer. In the case of propiconazole and dimethomorph, baseline resolution was also achieved by adding sodium cholate (a chiral surfactant) alone to the running buffer. Analysis of fortified water samples yielded recoveries ranging from 45 to 89% and method detection limits ranging from 0.18 to 2.1 ppb. The reported capillary electrophoresis methods are simple, rapid, and reproducible.

Sign in / Sign up

Export Citation Format

Share Document