Acyl Radical Addition to Activated Olefins: A Stereocontrolled Route to Polysubstituted Tetrahydrofurans and Lactones, and Application to the Total Synthesis of (+)-No. 2106 A

2017 ◽  
Vol 2017 (10) ◽  
pp. 1323-1330 ◽  
Author(s):  
Simon Grélaud ◽  
Jonathan Lusseau ◽  
Yannick Landais
Keyword(s):  
Total Synthesis ◽  
Radical Addition ◽  
Acyl Radical ◽  
Activated Olefins

Convergent Assembly of Polycyclic Ethers via Acyl Radical Addition to Unactivated Enol Ether

2006 ◽  
Vol 8 (25) ◽  
pp. 5801-5804 ◽  
Author(s):  
Masayuki Inoue ◽  
Yuuki Ishihara ◽  
Shuji Yamashita ◽  
Masahiro Hirama
Keyword(s):  
Radical Addition ◽  
Enol Ether ◽  
Acyl Radical ◽  
Convergent Assembly ◽  
Polycyclic Ethers

Direct Acyl Radical Addition to 2H-Indazoles Using Ag-Catalyzed Decarboxylative Cross-Coupling of α-Keto Acids

2018 ◽  
Vol 20 (9) ◽  
pp. 2711-2715 ◽  
Author(s):  
Ganganna Bogonda ◽  
Hun Young Kim ◽  
Kyungsoo Oh
Keyword(s):  
Cross Coupling ◽  
Radical Addition ◽  
Acyl Radical ◽  
Keto Acids

Total Synthesis of (−)-Martinellic Acid via Radical Addition−Cyclization−Elimination Reaction

2008 ◽  
Vol 73 (12) ◽  
pp. 4464-4475 ◽  
Author(s):  
Atsushi Shirai ◽  
Okiko Miyata ◽  
Norimitsu Tohnai ◽  
Mikiji Miyata ◽  
David J. Procter ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Radical Addition ◽  
Elimination Reaction ◽  
Martinellic Acid

Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde

2020 ◽  
Vol 142 (30) ◽  
pp. 13227-13234 ◽  
Author(s):  
Haruka Fujino ◽  
Takumi Fukuda ◽  
Masanori Nagatomo ◽  
Masayuki Inoue
Keyword(s):  
Total Synthesis ◽  
Radical Addition

scholarly journals Stereocontrolled Synthesis of 1,4‐Dicarbonyl Compounds by Photochemical Organocatalytic Acyl Radical Addition to Enals

2019 ◽  
Vol 58 (4) ◽  
pp. 1213-1217 ◽  
Author(s):  
Giulio Goti ◽  
Bartosz Bieszczad ◽  
Alberto Vega‐Peñaloza ◽  
Paolo Melchiorre
Keyword(s):  
Radical Addition ◽  
Acyl Radical ◽  
Dicarbonyl Compounds ◽  
Stereocontrolled Synthesis

Heterocycle synthesis via radical reactions

2008 ◽  
Vol 80 (4) ◽  
pp. 717-726 ◽  
Author(s):  
Takeaki Naito
Keyword(s):  
Total Synthesis ◽  
Heterocyclic Compounds ◽  
Alkyl Radical ◽  
Radical Addition ◽  
Synthetic Method ◽  
Asymmetric Total Synthesis ◽  
Heterocycle Synthesis ◽  
Leaving Group ◽  
Martinellic Acid ◽  
Type Radical

A novel synthetic method for the preparation of nitrogen-containing heterocycles via the route involving domino-type radical addition/cyclization reaction of oxime ethers is described. Alkyl radical addition/cyclization of oxime ethers carrying an appropriate leaving group proceeded smoothly to form the alkylated nitrogen-containing heterocyclic compounds. Additionally, tin-mediated radical addition/cyclization/elimination (RACE) reaction of oxime ethers is newly found and successfully applied to an asymmetric total synthesis of (-)-martinellic acid.

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