Short Regioselective Chemoenzymatic Synthesis and Biological Evaluation of 1-O-Acyl-2-O-(β-D-sulfoquinovopyranosyl)-sn-glycerols

2009 ◽  
Vol 2009 (34) ◽  
pp. 6019-6026 ◽  
Author(s):  
Milind Dangate ◽  
Laura Franchini ◽  
Fiamma Ronchetti ◽  
Takanari Arai ◽  
Akira Iida ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Synthesis And Biological Evaluation

scholarly journals Chemoenzymatic synthesis and biological evaluation of enantiomerically enriched 1-(β-hydroxypropyl)imidazolium- and triazolium-based ionic liquids

2013 ◽  
Vol 9 ◽  
pp. 516-525 ◽  
Author(s):  
Paweł Borowiecki ◽  
Małgorzata Milner-Krawczyk ◽  
Jan Plenkiewicz
Keyword(s):  
Ionic Liquids ◽  
Vinyl Acetate ◽  
Propylene Oxide ◽  
Ring Opening ◽  
Biological Evaluation ◽  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Alkyl Bromides ◽  
Wide Range ◽  
Synthesis And Biological Evaluation

Racemic 1-(β-hydroxypropyl)azoles were prepared by solvent-free direct regioselective ring opening of 1,2-propylene oxide with imidazole or 1,2,4-triazole. Lipase-catalyzed transesterification of alcohols with vinyl acetate resulted in kinetic enantiomers resolution. Separated (S)-enantiomers of (+)-1-(1H-imidazol-1-yl)propan-2-ol and (+)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol were quaternized with alkyl bromides or iodides, yielding novel optically active ionic liquids. Racemic salts were tested against a wide range of microorganisms.

Novel deoxy-selenylconduritols: chemoenzymatic synthesis and biological evaluation

2009 ◽  
Vol 20 (23) ◽  
pp. 2673-2676 ◽  
Author(s):  
Ana Bellomo ◽  
Ana Bertucci ◽  
Hélio Stefani ◽  
Álvaro Vázquez ◽  
David Gonzalez
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Chemoenzymatic Synthesis and Biological Evaluation of (-)-Conduramine C-4.

ChemInform ◽  
2008 ◽  
Vol 39 (11) ◽  
Author(s):  
Ana Bellomo ◽  
Cecilia Giacomini ◽  
Beatriz Brena ◽  
Gustavo Seoane ◽  
David Gonzalez
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Synthesis And Biological Evaluation

Chemoenzymatic Synthesis and Biological Evaluation of (−)‐Conduramine C‐4

2007 ◽  
Vol 37 (20) ◽  
pp. 3509-3518 ◽  
Author(s):  
Ana Bellomo ◽  
Cecilia Giacomini ◽  
Beatriz Brena ◽  
Gustavo Seoane ◽  
David Gonzalez
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Synthesis And Biological Evaluation

Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1α,25-dihydroxyvitamin D3

2004 ◽  
Vol 12 (20) ◽  
pp. 5443-5451 ◽  
Author(s):  
Vicente Gotor-Fernández ◽  
Susana Fernández ◽  
Miguel Ferrero ◽  
Vicente Gotor ◽  
Roger Bouillon ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Dihydroxyvitamin D3 ◽  
Synthesis And Biological Evaluation

Convergent chemoenzymatic synthesis and biological evaluation of a heparan sulfate proteoglycan syndecan-1 mimetic

2021 ◽  
Vol 57 (27) ◽  
pp. 3407-3410
Author(s):  
Jia Gao ◽  
Yongmei Xu ◽  
Jian Liu ◽  
Xuefei Huang
Keyword(s):  
Heparan Sulfate ◽  
Biological Evaluation ◽  
Heparan Sulfate Proteoglycan ◽  
Chemoenzymatic Synthesis ◽  
Sulfate Proteoglycan ◽  
Biological Studies ◽  
Synthesis Strategy ◽  
Synthesis And Biological Evaluation

A new convergent chemoenzymatic synthesis strategy has been established to efficiently synthesize a mimetic of structurally well-defined heparan sulfate proteoglycan syndecan-1 glyco-polypeptide at a milligram scale to enable biological studies.

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