Kinetics of Bis(p-nitrophenyl)phosphate (BNPP) Hydrolysis Reactions with Trivalent Lanthanide Complexes ofN-Hydroxyethyl(ethylenediamine)-N,N′,N′-triacetate (HEDTA)

2009 ◽  
Vol 2009 (8) ◽  
pp. 1036-1042 ◽  
Author(s):  
C. Allen Chang ◽  
Yu-Ping Chen ◽  
Chih-Hsiang Hsiao
Keyword(s):  
Lanthanide Complexes ◽  
Nitrophenyl Phosphate ◽  
Trivalent Lanthanide ◽  
Kinetics Of ◽  
Bnpp Hydrolysis ◽  
Hydrolysis Reactions

scholarly journals Controlling the Kinetics of an Enzymatic Reaction through Enzyme or Substrate Confinement into Lipid Mesophases with Tunable Structural Parameters

2020 ◽  
Vol 21 (14) ◽  
pp. 5116
Author(s):  
Marco Mendozza ◽  
Arianna Balestri ◽  
Costanza Montis ◽  
Debora Berti
Keyword(s):  
Reaction Kinetics ◽  
Self Assembly ◽  
Liquid Crystalline ◽  
Structural Parameters ◽  
Enzymatic Reaction ◽  
X Ray Scattering ◽  
Nitrophenyl Phosphate ◽  
Vis Spectroscopy ◽  
Kinetics Of ◽  
Enzyme Alkaline Phosphatase

Lipid liquid crystalline mesophases, resulting from the self-assembly of polymorphic lipids in water, have been widely explored as biocompatible drug delivery systems. In this respect, non-lamellar structures are particularly attractive: they are characterized by complex 3D architectures, with the coexistence of hydrophobic and hydrophilic regions that can conveniently host drugs of different polarities. The fine tunability of the structural parameters is nontrivial, but of paramount relevance, in order to control the diffusive properties of encapsulated active principles and, ultimately, their pharmacokinetics and release. In this work, we investigate the reaction kinetics of p-nitrophenyl phosphate conversion into p-nitrophenol, catalysed by the enzyme Alkaline Phosphatase, upon alternative confinement of the substrate and of the enzyme into liquid crystalline mesophases of phytantriol/H2O containing variable amounts of an additive, sucrose stearate, able to swell the mesophase. A structural investigation through Small-Angle X-ray Scattering, revealed the possibility to finely control the structure/size of the mesophases with the amount of the included additive. A UV–vis spectroscopy study highlighted that the enzymatic reaction kinetics could be controlled by tuning the structural parameters of the mesophase, opening new perspectives for the exploitation of non-lamellar mesophases for confinement and controlled release of therapeutics.

Kinetic Isotope Effects and Stereochemical Studies on a Ribonuclease Model: Hydrolysis Reactions of Uridine 3′-Nitrophenyl Phosphate

2000 ◽  
Vol 28 (3) ◽  
pp. 119-133 ◽  
Author(s):  
Alvan C. Hengge ◽  
Karol S. Bruzik ◽  
Aleksandra E. Tobin ◽  
W.W. Cleland ◽  
Ming-Daw Tsai
Keyword(s):  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Kinetic Isotope ◽  
Nitrophenyl Phosphate ◽  
Hydrolysis Reactions

Kinetics of the solvolytic reaction between polymer hydrogels carrying oxime groups and O,O′-diethyl-O-p-nitrophenyl phosphate

1991 ◽  
Vol 33 (5) ◽  
pp. 1006-1012 ◽  
Author(s):  
A.K. Andrianov ◽  
Yu.A. Osinkin ◽  
V.Ye. Igonin ◽  
N.A. Platé
Keyword(s):  
Polymer Hydrogels ◽  
Nitrophenyl Phosphate ◽  
Kinetics Of

Photo-enhanced hydrolysis of bis(4-nitrophenyl) phosphate using Cu(ii) bipyridine-capped plasmonic nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 41618-41621 ◽  
Author(s):  
Scott A. Trammell ◽  
Rafaela Nita ◽  
Brett Martin ◽  
Martin H. Moore ◽  
Jake Fontana ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Fold Increase ◽  
Green Laser ◽  
Plasmonic Nanoparticles ◽  
Nitrophenyl Phosphate ◽  
Hydrolysis Of ◽  
Bnpp Hydrolysis

A 1000-fold increase in the rate of BNPP hydrolysis occurs under green laser irradiation of a copper(ii) complex on gold.

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