scholarly journals Comparison of spleen transcriptomes of two wild rodent species reveals differences in the immune response against Borrelia afzelii

2020 ◽  
Vol 10 (13) ◽  
pp. 6421-6434
Author(s):  
Xiuqin Zhong ◽  
Max Lundberg ◽  
Lars Råberg
Keyword(s):  
Immune Response ◽  
Rodent Species ◽  
Wild Rodent ◽  
Borrelia Afzelii

scholarly journals Differential Tick Burdens May Explain Differential Borrelia afzelii and Borrelia garinii Infection Rates among Four, Wild, Rodent Species in Hokkaido, Japan

2013 ◽  
Vol 75 (6) ◽  
pp. 785-790 ◽  
Author(s):  
Kyle R. TAYLOR ◽  
Ai TAKANO ◽  
Satoru KONNAI ◽  
Michito SHIMOZURU ◽  
Hiroki KAWABATA ◽  
...  
Keyword(s):  
Rodent Species ◽  
Infection Rates ◽  
Wild Rodent ◽  
Borrelia Garinii ◽  
Borrelia Afzelii

The effect of varying calcium intake on calcium metabolism in wild rodent species

1992 ◽  
Vol 227 (1) ◽  
pp. 29-42 ◽  
Author(s):  
R. F. Shore ◽  
R. J. Balment ◽  
D. W. Yalden
Keyword(s):  
Calcium Intake ◽  
Calcium Metabolism ◽  
Rodent Species ◽  
Wild Rodent

scholarly journals CLONAL NATURE OF THE IMMUNE RESPONSE TO PHOSPHORYLCHOLINE

1974 ◽  
Vol 140 (3) ◽  
pp. 673-686 ◽  
Author(s):  
J. Latham Claflin ◽  
Joseph M. Davie
Keyword(s):  
Immune Response ◽  
Binding Site ◽  
Inbred Mouse ◽  
Binding Specificity ◽  
Rodent Species ◽  
Mouse Strains ◽  
Inbred Mouse Strains ◽  
Myeloma Protein ◽  
Clonal Nature ◽  
Different Strains

A new idiotypic determinant(s) on mouse anti-PC antibodies is described. Antibodies to the determinant(s) were raised in rabbits by immunization with HOPC 8, a PC-binding myeloma protein, and were isolated from HOPC 8 immunoadsorbent by elution with PC. These antibodies react with binding site determinants on anti-PC antibodies raised in all 15 inbred mouse strains tested regardless of histocompatibility or allotype, but fail to react with antibodies of other specificities or with anti-PC antibodies raised in other rodent species. These results correlate closely with other studies which show similar binding specificity of anti-PC antibodies raised in 17 different strains of mice. The site-associated idiotypic determinant(s) is clearly distinct from that detected by mouse anti-HOPC 8 antisera. This latter determinant(s) is present on anti-PC antibodies of only a few strains of mice and may not be in the binding site.

scholarly journals Diverse Genotypes and Species of Cryptosporidium in Wild Rodent Species from the West Coast of the USA and Implications for Raw Produce Safety and Microbial Water Quality

2021 ◽  
Vol 9 (4) ◽  
pp. 867
Author(s):  
Xunde Li ◽  
Edward Robert Atwill
Keyword(s):  
Public Health ◽  
West Coast ◽  
Cryptosporidium Species ◽  
Ground Squirrels ◽  
Rodent Species ◽  
Deer Mice ◽  
Wild Rodents ◽  
Wild Rodent ◽  
The West ◽  
The Usa

Cryptosporidium spp. are protozoan parasites that infect perhaps all vertebrate animals, with a subset of species and genotypes that function as food- and waterborne pathogens. The objective of this work was to collate the Cryptosporidium species and genotypes from common wild rodents on the west coast of the USA and update the information regarding the zoonotic potential of Cryptosporidium from these ubiquitous wild species. Representative sequences of the 18S rRNA gene for a unique set of Cryptosporidium isolates obtained from deer mice, house mice, mountain beavers, yellow-bellied marmot, long-tailed vole, California ground squirrels, Belding’s ground squirrels, and a golden-mantled ground squirrel in GenBank were selected for phylogenetic analysis. Phylogenetic and BLAST analysis indicated that 4 (18%) of the 22 unique Cryptosporidium sequences from these wild rodent species were 99.75% to 100% identical to known zoonotic species (C. parvum, C. ubiquitum, C. xiaoi), suggesting that a minority of these representative Cryptosporidium isolates could have a public health impact through food and waterborne routes of human exposure. These zoonotic isolates were shed by deer mice and a yellow-bellied marmot from California, and from a mountain beaver trapped in Oregon. In addition, the group of unique Cryptosporidium isolates from deer mice and ground dwelling squirrels exhibited considerable DNA diversity, with multiple isolates appearing to be either host-limited or distributed throughout the various clades within the phylogenetic tree representing the various Cryptosporidium species from host mammals. These results indicate that only a subset of the unique Cryptosporidium genotypes and species obtained from wild rodents on the US west coast are of public health concern; nevertheless, given the geographic ubiquity of many of these host species and often high density at critical locations like municipal watersheds or produce production fields, prudent pest control practices are warranted to minimize the risks of water- and foodborne transmission to humans.

scholarly journals Decomposing variation in immune response in a wild rodent population

2019 ◽  
Author(s):  
Klara M. Wanelik ◽  
Mike Begon ◽  
Elena Arriero ◽  
Janette E. Bradley ◽  
Ida M. Friberg ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Immune Response ◽  
Individual Variation ◽  
Natural Variation ◽  
Wild Population ◽  
Microtus Agrestis ◽  
Wild Rodent ◽  
Rodent Population ◽  
Immune Pathways ◽  
Underlying Processes

AbstractIndividuals vary in their immune response and, as a result, some are more susceptible to infectious disease than others. Little is known about which components of immune pathways are responsible for this variation, but understanding these underlying processes could allow us to predict the outcome of infection for an individual, and to manage their health more effectively. In this study, we describe transcriptome-wide variation in immune response (to a standardised challenge) in a wild population of field voles (Microtus agrestis). We find that this variation can be categorised into three main types. We also identify markers, across these three categories, which display particularly strong individual variation in response. This work shows how a simple standardised challenge performed on a natural population can reveal complex patterns of natural variation in immune response.

High in vitro endotoxin responsiveness of macrophages from an endotoxin-resistant wild rodent species, Sigmodon hispidus

1994 ◽  
Vol 18 (2) ◽  
pp. 147-153 ◽  
Author(s):  
C.Brad Dabbert ◽  
Robert L. Lochmiller ◽  
Jing-Ren Zhang ◽  
Charles W. Qualls ◽  
Kim Burnham
Keyword(s):  
Rodent Species ◽  
Sigmodon Hispidus ◽  
Wild Rodent
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