A narrative review of systematic reviews on adherence to psoriasis treatments

2021 ◽  
Author(s):  
Armaan Guraya ◽  
Uros Rakita ◽  
Caroline L. Porter ◽  
Steven R. Feldman
2018 ◽  
Vol 9 (4) ◽  
pp. 527-539 ◽  
Author(s):  
Hannah Wood ◽  
Annette O'Connor ◽  
Jan Sargeant ◽  
Julie Glanville

2019 ◽  
Vol 73 (4) ◽  
pp. 154-162 ◽  
Author(s):  
Ibrahim Nadeem ◽  
Mohammed Z. Rahman ◽  
Yasser Ad‐Dab'bagh ◽  
Mahmood Akhtar

2020 ◽  
Vol 35 (6) ◽  
pp. 1830-1835 ◽  
Author(s):  
Jennifer S. Lin ◽  
M. Hassan Murad ◽  
Brian Leas ◽  
Jonathan R. Treadwell ◽  
Roger Chou ◽  
...  

2020 ◽  
Vol 8 (10) ◽  
pp. 1501
Author(s):  
Gabriella D’Angiolella ◽  
Pamela Tozzo ◽  
Sarah Gino ◽  
Luciana Caenazzo

The oral microbiome harbours microbial community signatures that differ among individuals, highlighting that it could be highly individualizing and potentially unique to each individual. Therefore, the oral microbial traces collected in crime scenes could produce investigative leads. This narrative review will describe the current state-of-the-art of how the salivary microbiome could be exploited as a genetic signature to make inferences in the forensic field. This review has been performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines. Even if further studies are needed to relate the variation in the oral microbiome to specific factors, in order to understand how the salivary microbiome is influenced by an individual’s lifestyle, by reviewing the studies published so far, it is clear that the oral microbial analysis could become a useful forensic tool. Even if promising, caution is required in interpreting the results and an effort to direct research towards studies that fill the current knowledge gaps is certainly useful.


2002 ◽  
Vol 16 (1) ◽  
pp. 17-21 ◽  
Author(s):  
John WD McDonald ◽  
Jeffrey Mahon ◽  
Kelly Zarnke ◽  
Brian Feagan ◽  
Lorinda Simms ◽  
...  

BACKGROUND: Clinicians often rely on review material rather than analysis of primary research to guide therapy. Systematic reviews use methods to insure thoroughness and to minimize bias, but many clinicians are not familiar with systematic reviews and continue to rely on narrative reviews.OBEJCTIVES: To determine whether a traditional narrative review or a systematic review is perceived to be more useful.METHODS: A clinical scenario (patient with chronic Crohn’s disease considered for azathioprine therapy) was circulated to gastroenterologists, along with a narrative review of therapy (including azathioprine) for inflammatory bowel disease written by an acknowledged expert, or with a systematic Cochrane review of the use of azathioprine for this disease. Whether knowledge of authorship and journal source influences the perception of usefulness of a narrative review was investigated.RESULTS: The Cochrane review was rated significantly more highly than the narrative review on a 100 mm visual analogue scale (21.3 mm; 95% CI 14.5 to 28 mm). The proportion of respondents who considered the review to be a useful guide was also higher in the group that received the Cochrane review (91%) than in the group that received the narrative review, with author and journal concealed (62%) or identified (70%) (P<0.001 for both comparisons). Ratings from the two groups that received the narrative review were not significantly different.CONCLUSIONS: The focused systematic review was perceived to be more useful than a traditional broad narrative review as a guide to making a decision concerning the use of specific therapy. The possible strengths of systematic reviews should be more fully investigated. If there is additional evidence supporting their greater value to clinicians, they should be made more widely available to clinicians and their strengths should be publicized.


2018 ◽  
Vol 42 (5) ◽  
pp. 568 ◽  
Author(s):  
Rebekah Eden ◽  
Andrew Burton-Jones ◽  
Ian Scott ◽  
Andrew Staib ◽  
Clair Sullivan

Objective The transition to digital hospitals is fast-moving. Although US hospitals are further ahead than some others in implementing eHealth technologies, their early experiences are not necessarily generalisable to contemporary healthcare because both the systems and technologies have been rapidly evolving. It is important to provide up-to-date assessments of the evidence available. The aim of this paper is to provide an assessment of the current literature on the effects to be expected from hospital implementations of eHealth technologies. Methods A narrative review was conducted of systematic reviews investigating the effects of eHealth technologies (clinical decision support systems (CDSS), computerised provider order entry (CPOE), ePrescribing, electronic medical records (EMRs)) published between November 2015 and August 2017 and compared the findings with those of a previous narrative review that examined studies published between January 2010 and October 2015. The same search strategy and selection criteria were used in both studies. Results Of the seven relevant articles, three (42.9%) examined the effects of more than one eHealth system: only two (28.6%) studies were high quality, three (42.9%) were of intermediate quality and two (28.6%) were of low quality. We identified that EMRs are largely associated with conflicting findings. Previous reviews suggested that CPOE are associated with significant positive results of cost savings, organisational efficiency gains, less resource utilisation and improved individual performance. However, these effects were not investigated in the more recent reviews, and only mixed findings for communication between clinicians were reported. Similarly, for ePrescribing, later reviews reported limited evidence of benefits, although when coupled with CDSS, more consistent positive findings were reported. Conclusion This overview can help inform other hospitals in Australia and elsewhere of the likely effects resulting from eHealth technologies. The findings suggest that the effects of these systems are largely mixed, but there are positive findings, which encourage ongoing digital transformation of hospital practice. What is known about the topic? Governments are increasingly devoting substantial resources towards implementing eHealth technologies in hospital practice with the goals of improving clinical and financial outcomes. Yet, these outcomes are yet to be fully realised in practice and conflicting findings are often reported in the literature. What does this paper add? This paper extends a previous narrative review of systematic reviews and categorises the effects of eHealth technologies into a typology of outcomes to enable overall findings to be reported and comparisons to be made. In doings so, we synthesise 7 years of eHealth effects. Mixed results are largely reported for EMRs, with many benefits being compromised by practices stemming from resistance to EMRs. Limited evidence of effectiveness exists for CPOE and ePrescribing. CDSS are associated with the most consistent positive findings for clinician- and hospital-level effects. We observed renewed interest in the literature for the effect of eHealth technologies on communication both between clinicians and with patients. Other new insights have emerged relating to effects on clinical judgement, changing practice and staff retention. What are the implications for practitioners? eHealth technologies have the potential to positively affect clinical and financial outcomes. However, these benefits are not guaranteed, and mixed results are often reported. This highlights the need for hospitals and decision makers to clearly identify and act on the drivers of successful implementations if eHealth technologies are to facilitate the creation of new, more effective models of patient care in an increasingly complex healthcare environment.


2020 ◽  
Vol 138 (4) ◽  
pp. 336-344
Author(s):  
Ronald Luiz Gomes Flumignan ◽  
Luis Carlos Uta Nakano ◽  
Patricia Irene Ferreira Pascoal ◽  
Brena Costa dos Santos ◽  
Rebeca Mangabeira Correia ◽  
...  

2017 ◽  
Vol 181 (8) ◽  
pp. 198-207 ◽  
Author(s):  
P. Lees ◽  
L. Pelligand ◽  
M. Whiting ◽  
D. Chambers ◽  
P-L. Toutain ◽  
...  

Part 2 of this narrative review outlines the theoretical and practical bases for assessing the efficacy and effectiveness of conventional medicines and homeopathic products. Known and postulated mechanisms of action are critically reviewed. The evidence for clinical efficacy of products in both categories, in the form of practitioner experience, meta-analysis and systematic reviews of clinical trial results, is discussed. The review also addresses problems and pitfalls in assessing data, and the ethical and negative aspects of pharmacology and homeopathy in veterinary medicine.


Sign in / Sign up

Export Citation Format

Share Document