Spontaneous Formation of Biocompatible Vesicles in Aqueous Mixtures of Amino Acid-Based Cationic Surfactants and SDS/SDBS

ChemPhysChem ◽  
2010 ◽  
Vol 12 (2) ◽  
pp. 369-378 ◽  
Author(s):  
Anshupriya Shome ◽  
Tanmoy Kar ◽  
Prasanta K. Das
Keyword(s):  
Amino Acid ◽  
Cationic Surfactants ◽  
Aqueous Mixtures ◽  
Spontaneous Formation

scholarly journals Efficient DNA Condensation Induced by Chiral β-Amino Acid-Based Cationic Surfactants

2021 ◽  
Author(s):  
Bernat Pi-Boleda ◽  
Sravani Ramisetty ◽  
Ona Illa ◽  
Vicenç Branchadell ◽  
Rita S. Dias ◽  
...  
Keyword(s):  
Amino Acid ◽  
Cationic Surfactants ◽  
Dna Condensation

scholarly journals Biological and Physico-Chemical Characteristics of Arginine-Rich Peptide Gemini Surfactants with Lysine and Cystine Spacers

2021 ◽  
Vol 22 (7) ◽  
pp. 3299
Author(s):  
Damian Neubauer ◽  
Maciej Jaśkiewicz ◽  
Marta Bauer ◽  
Agata Olejniczak-Kęder ◽  
Emilia Sikorska ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Amino Acid ◽  
Cationic Surfactants ◽  
Antimicrobial Agents ◽  
Gemini Surfactants ◽  
Antimicrobial Activities ◽  
Critical Aggregation Concentration ◽  
Cytotoxic Activities ◽  
Candida Sp ◽  
Enhanced Selectivity

Ultrashort cationic lipopeptides (USCLs) and gemini cationic surfactants are classes of potent antimicrobials. Our recent study has shown that the branching and shortening of the fatty acids chains with the simultaneous addition of a hydrophobic N-terminal amino acid in USCLs result in compounds with enhanced selectivity. Here, this approach was introduced into arginine-rich gemini cationic surfactants. L-cystine diamide and L-lysine amide linkers were used as spacers. Antimicrobial activity against planktonic and biofilm cultures of ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) strains and Candida sp. as well as hemolytic and cytotoxic activities were examined. Moreover, antimicrobial activity in the presence of human serum and the ability to form micelles were evaluated. Membrane permeabilization study, serum stability assay, and molecular dynamics were performed. Generally, critical aggregation concentration was linearly correlated with hydrophobicity. Gemini surfactants were more active than the parent USCLs, and they turned out to be selective antimicrobial agents with relatively low hemolytic and cytotoxic activities. Geminis with the L-cystine diamide spacer seem to be less cytotoxic than their L-lysine amide counterparts, but they exhibited lower antibiofilm and antimicrobial activities in serum. In some cases, geminis with branched fatty acid chains and N-terminal hydrophobic amino acid resides exhibited enhanced selectivity to pathogens over human cells.

Spontaneous formation of nanometer scale tubular vesicles in aqueous mixtures of lipid and block copolymer amphiphiles

Soft Matter ◽  
2017 ◽  
Vol 13 (6) ◽  
pp. 1107-1115 ◽  
Author(s):  
Seng Koon Lim ◽  
Andrew S. W. Wong ◽  
Hans-Peter M. de Hoog ◽  
Padmini Rangamani ◽  
Atul N. Parikh ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Nanometer Scale ◽  
Aqueous Mixtures ◽  
Spontaneous Formation

Transition from Micelles to Vesicles in Aqueous Mixtures of Anionic and Cationic Surfactants

Langmuir ◽  
1997 ◽  
Vol 13 (21) ◽  
pp. 5531-5538 ◽  
Author(s):  
Olle Söderman ◽  
Kathleen L. Herrington ◽  
Eric W. Kaler ◽  
David D. Miller
Keyword(s):  
Cationic Surfactants ◽  
Aqueous Mixtures ◽  
Anionic And Cationic Surfactants

Spontaneous Formation of Vesicles and Dispersed Cubic and Hexagonal Particles in Amino Acid-Based Catanionic Surfactant Systems

Langmuir ◽  
2006 ◽  
Vol 22 (13) ◽  
pp. 5588-5596 ◽  
Author(s):  
Mónica Rosa ◽  
Maria Rosa Infante ◽  
Maria da G. Miguel ◽  
Björn Lindman
Keyword(s):  
Amino Acid ◽  
Catanionic Surfactant ◽  
Spontaneous Formation ◽  
Surfactant Systems

Amino Acid Based Cationic Surfactants in Aqueous Solution:  Physicochemical Study and Application of Supramolecular Chirality in Ketone Reduction

Langmuir ◽  
2005 ◽  
Vol 21 (23) ◽  
pp. 10398-10404 ◽  
Author(s):  
Sangita Roy ◽  
Debapratim Das ◽  
Antara Dasgupta ◽  
Rajendra Narayan Mitra ◽  
Prasanta Kumar Das
Keyword(s):  
Aqueous Solution ◽  
Amino Acid ◽  
Cationic Surfactants ◽  
Physicochemical Study ◽  
Ketone Reduction ◽  
Supramolecular Chirality
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