Hydrophobic magnetic nanoparticles assisted catanionic surfactant supramolecular solvent microextraction of multiresidue antibiotics in water samples

A novel extraction technique i.e. hydrophobic magnetic nanoparticles (MNPs)-assisted in situ supramolecular solvent (SUPRAS) microextraction was proposed, and it was applied for the analysis of sulfonamides (SAs) and fluoroquinolones (FQs)...

Mixed Alkyltrimethylammonium-Alkylcarboxylate Surfactants Systems: A Potential Anti-Proliferation Agent for MDA-MB-231 Cancer Cell Line

Series of catanionic based alkyltrimethylammonium-alkylcarboxylate surfactants systems having different degree of alkyl chain length asymmetry were prepared and tested for their cytotoxicity against both fibroblast 3T3 and breast cancer MDA-MB-231 cell lines. Catanionic surfactant with the highest alkyl chain length possessed significant potent cytotoxicity, with a half maximal inhibitory concentration (IC50) of 4.04 ± 0.06 μM on MDA-MB-231 cell line. Combination of anti-cancer agent (tocotrienol rich fraction,TRF; and curcumin, respectively)with the catanionic at different weight ratios was found to exert lower cytotoxicity on both cell lines as compared to the treated cells with catanionic only. Noticeably, combination of TRF withcatanionic showed higher anti-cancer activities than the incorporation of curcumin with catanionic (resulted low IC50 value). Combination index (CI) of both anti-cancer agent (TRF and curcumin) and catanionic mixtures indicated antagonistic effect (more than 1), respectively, which may explained catanionic surfactant having long alkyl chain length has the potential to act as anti-cancer agent in its pristine form and less effective with other anti-cancer agents combination.

Transmembrane potential in vesicles formed by catanionic surfactant mixtures in an aqueous salt solution

Simple theory shows the effects of vesicle structure and the composition of the medium on the transmembrane potential.

DNA thermotropic liquid crystals controlled by positively charged catanionic bilayer vesicles

We report DNA thermotropic liquid crystal (TLC) formation by positively charged catanionic surfactant bilayer vesicles.