scholarly journals Evidence for a regional specificity in the density and distribution of noradrenergic varicosities in rat cortex

2013 ◽  
Vol 521 (10) ◽  
pp. 2195-2207 ◽  
Author(s):  
Kara L. Agster ◽  
Carlos A. Mejias-Aponte ◽  
Brian D. Clark ◽  
Barry D. Waterhouse
2017 ◽  
pp. 142-149 ◽  
Author(s):  
E. Pitukhin ◽  
S. Shabaeva ◽  
I. Stepus ◽  
D. Moroz

The paper deals with comparative analysis of occupations in the regional labor market. Occupation is treated as a multi-dimensional space of characte- ristics, whereas a scalar form of a characteristic makes it possible to carry out a comparative analysis of occupations. Using cluster analysis of a pilot region indicators five meaningfully interpretable clusters of occupations were identified, reflecting their regional specificity.


2021 ◽  
Vol 7 (15) ◽  
pp. eabe8978
Author(s):  
Álvaro Herrero-Navarro ◽  
Lorenzo Puche-Aroca ◽  
Verónica Moreno-Juan ◽  
Alejandro Sempere-Ferràndez ◽  
Ana Espinosa ◽  
...  

Neural cell diversity is essential to endow distinct brain regions with specific functions. During development, progenitors within these regions are characterized by specific gene expression programs, contributing to the generation of diversity in postmitotic neurons and astrocytes. While the region-specific molecular diversity of neurons and astrocytes is increasingly understood, whether these cells share region-specific programs remains unknown. Here, we show that in the neocortex and thalamus, neurons and astrocytes express shared region-specific transcriptional and epigenetic signatures. These signatures not only distinguish cells across these two brain regions but are also detected across substructures within regions, such as distinct thalamic nuclei, where clonal analysis reveals the existence of common nucleus-specific progenitors for neurons and astrocytes. Consistent with their shared molecular signature, regional specificity is maintained following astrocyte-to-neuron reprogramming. A detailed understanding of these regional-specific signatures may thus inform strategies for future cell-based brain repair.


2017 ◽  
Vol 95 (11) ◽  
pp. 2297-2306 ◽  
Author(s):  
Sarah Sonnay ◽  
João M. N. Duarte ◽  
Nathalie Just ◽  
Rolf Gruetter
Keyword(s):  

Synapse ◽  
1997 ◽  
Vol 27 (1) ◽  
pp. 79-82 ◽  
Author(s):  
David L. Willins ◽  
Ariel Y. Deutch ◽  
Bryan L. Roth
Keyword(s):  

2010 ◽  
Vol 24 (7) ◽  
pp. 2053-2057 ◽  
Author(s):  
Timothy J. Shafer ◽  
Michael F. Hughes
Keyword(s):  

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