Associative pairing involving monocular stimulation selectively mobilizes a subclass of GABAergic interneurons in the mouse visual cortex

2009 ◽  
Vol 516 (6) ◽  
pp. 482-492 ◽  
Author(s):  
Monika Liguz-Lecznar ◽  
Wioletta J. Waleszczyk ◽  
Renata Zakrzewska ◽  
Jolanta Skangiel-Kramska ◽  
Malgorzata Kossut
Keyword(s):  
Visual Cortex ◽  
Gabaergic Interneurons ◽  
Monocular Stimulation ◽  
Mouse Visual Cortex

scholarly journals Aberrant development of excitatory circuits to inhibitory neurons in the primary visual cortex after neonatal binocular enucleation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rongkang Deng ◽  
Joseph P. Y. Kao ◽  
Patrick O. Kanold
Keyword(s):  
Visual Cortex ◽  
Nmda Receptors ◽  
Laser Scanning ◽  
Inhibitory Neurons ◽  
Gabaergic Interneurons ◽  
Cortical Circuits ◽  
Retinal Input ◽  
Layer 4 ◽  
Ampa And Nmda Receptors ◽  
Laser Scanning Photostimulation

AbstractThe development of GABAergic interneurons is important for the functional maturation of cortical circuits. After migrating into the cortex, GABAergic interneurons start to receive glutamatergic connections from cortical excitatory neurons and thus gradually become integrated into cortical circuits. These glutamatergic connections are mediated by glutamate receptors including AMPA and NMDA receptors and the ratio of AMPA to NMDA receptors decreases during development. Since previous studies have shown that retinal input can regulate the early development of connections along the visual pathway, we investigated if the maturation of glutamatergic inputs to GABAergic interneurons in the visual cortex requires retinal input. We mapped the spatial pattern of glutamatergic connections to layer 4 (L4) GABAergic interneurons in mouse visual cortex at around postnatal day (P) 16 by laser-scanning photostimulation and investigated the effect of binocular enucleations at P1/P2 on these patterns. Gad2-positive interneurons in enucleated animals showed an increased fraction of AMPAR-mediated input from L2/3 and a decreased fraction of input from L5/6. Parvalbumin-expressing (PV) interneurons showed similar changes in relative connectivity. NMDAR-only input was largely unchanged by enucleation. Our results show that retinal input sculpts the integration of interneurons into V1 circuits and suggest that the development of AMPAR- and NMDAR-only connections might be regulated differently.

Fourier imaging of experience-dependent positional map shift in the mouse visual cortex

2010 ◽  
Vol 68 ◽  
pp. e267
Author(s):  
Kohei Yoshitake ◽  
Manavu Tohmi ◽  
Ryuichi Hishida ◽  
Takeshi Yagi ◽  
Katsuei Shibuki
Keyword(s):  
Visual Cortex ◽  
Fourier Imaging ◽  
Mouse Visual Cortex

scholarly journals Correction: Dynamic Remodeling of Dendritic Arbors in GABAergic Interneurons of Adult Visual Cortex

PLoS Biology ◽  
2006 ◽  
Vol 4 (5) ◽  
pp. e126 ◽  
Author(s):  
Wei-Chung Allen Lee ◽  
Hayden Huang ◽  
Guoping Feng ◽  
Joshua R Sanes ◽  
Emery N Brown ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Gabaergic Interneurons ◽  
Dendritic Arbors

Attention Decorrelates Sensory and Motor Signals in the Mouse Visual Cortex

2021 ◽  
Author(s):  
Mohammad Abdolrahmani ◽  
Dmitry R. Lyamzin ◽  
Ryo Aoki ◽  
Andrea Benucci
Keyword(s):  
Visual Cortex ◽  
Mouse Visual Cortex ◽  
Motor Signals
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