Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-Selective Inhibitors

ChemMedChem ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. 657-664 ◽  
Author(s):  
Takayoshi Suzuki ◽  
Nobusuke Muto ◽  
Masashige Bando ◽  
Yukihiro Itoh ◽  
Ayako Masaki ◽  
...  
Keyword(s):  
Biological Activity ◽  
Histone Deacetylase ◽  
Selective Inhibitors ◽  
Design Synthesis ◽  
Histone Deacetylase 8

scholarly journals Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors

2017 ◽  
Vol 8 (8) ◽  
pp. 824-829 ◽  
Author(s):  
Taha Y. Taha ◽  
Shaimaa M. Aboukhatwa ◽  
Rachel C. Knopp ◽  
Naohiko Ikegaki ◽  
Hazem Abdelkarim ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Biological Evaluation ◽  
Selective Inhibitors ◽  
Design Synthesis ◽  
Histone Deacetylase 8 ◽  
Synthesis And Biological Evaluation

Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries

2012 ◽  
Vol 55 (22) ◽  
pp. 9562-9575 ◽  
Author(s):  
Takayoshi Suzuki ◽  
Yosuke Ota ◽  
Masaki Ri ◽  
Masashige Bando ◽  
Aogu Gotoh ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Histone Deacetylase ◽  
Selective Inhibitors ◽  
Histone Deacetylase 8

Design, Synthesis, and Biological Activity of a Novel Series of Human Sirtuin-2-Selective Inhibitors

2012 ◽  
Vol 55 (12) ◽  
pp. 5760-5773 ◽  
Author(s):  
Takayoshi Suzuki ◽  
Mohammed Naseer Ahmed Khan ◽  
Hideyuki Sawada ◽  
Erika Imai ◽  
Yukihiro Itoh ◽  
...  
Keyword(s):  
Biological Activity ◽  
Selective Inhibitors ◽  
Design Synthesis

Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors

2009 ◽  
Vol 52 (9) ◽  
pp. 2909-2922 ◽  
Author(s):  
Nobuaki Suzuki ◽  
Takayoshi Suzuki ◽  
Yosuke Ota ◽  
Tatsuya Nakano ◽  
Masaaki Kurihara ◽  
...  
Keyword(s):  
Biological Activity ◽  
Histone Deacetylase ◽  
Boronic Acid ◽  
Histone Deacetylase Inhibitors ◽  
Design Synthesis

scholarly journals Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors

2012 ◽  
Vol 20 (1) ◽  
pp. 183-194 ◽  
Author(s):  
Mithun R. Raje ◽  
Kenneth Knott ◽  
Yugesh Kharel ◽  
Philippe Bissel ◽  
Kevin R. Lynch ◽  
...  
Keyword(s):  
Biological Activity ◽  
Sphingosine Kinase ◽  
Selective Inhibitors ◽  
Design Synthesis ◽  
Sphingosine Kinase 2

Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors

ChemMedChem ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. 694-702 ◽  
Author(s):  
Stefania Terracciano ◽  
Maria Giovanna Chini ◽  
Raffaele Riccio ◽  
Ines Bruno ◽  
Giuseppe Bifulco
Keyword(s):  
Biological Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Tertiary Amines ◽  
Design Synthesis

Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors

2007 ◽  
Vol 17 (15) ◽  
pp. 4208-4212 ◽  
Author(s):  
Takayoshi Suzuki ◽  
Shinya Hisakawa ◽  
Yukihiro Itoh ◽  
Nobuaki Suzuki ◽  
Katsumasa Takahashi ◽  
...  
Keyword(s):  
Biological Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Folate Receptor ◽  
Design Synthesis
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