ChemInform Abstract: Combinatorial Synthesis of Spiro[indoline-3,2′-pyrrole] Derivatives via a Three-Component Reaction under Catalyst-Free Conditions.

ChemInform ◽  
2016 ◽  
Vol 47 (24) ◽  
Author(s):  
Guanghao Shi ◽  
Xinwei He ◽  
Yongjia Shang ◽  
Meihua Xie
Keyword(s):  
Combinatorial Synthesis ◽  
Pyrrole Derivatives ◽  
Catalyst Free ◽  
Three Component Reaction

Combinatorial synthesis of spiro[indoline-3,2′-pyrrole] derivatives via a three-component reaction under catalyst-free conditions

RSC Advances ◽  
2016 ◽  
Vol 6 (13) ◽  
pp. 10412-10418 ◽  
Author(s):  
Guanghao Shi ◽  
Xinwei He ◽  
Yongjia Shang ◽  
Meihua Xie
Keyword(s):  
Amino Acid ◽  
Combinatorial Synthesis ◽  
Pyrrole Derivatives ◽  
Catalyst Free ◽  
Three Component Reaction ◽  
Acid Esters

Reported here is a convenient catalyst-free method for preparing a series of spiro[indoline-3,2′-pyrroles] from a three-component reaction of isatins, α-amino acid and phenylpropiolic acid esters in refluxing isopropanol with high regioselectivity and yields.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

Synthesis of isoxazolidines via catalyst-free one-pot three-component cycloaddition of sulfoxonium ylides, nitrosoarenes and alkenes

2021 ◽  
Author(s):  
Xing Li ◽  
Pingan Zhai ◽  
Yongsheng Fang ◽  
Wenhui Li ◽  
Honghong Chang ◽  
...  
Keyword(s):  
One Pot ◽  
Catalyst Free ◽  
Practical Strategy ◽  
Three Component Reaction

A general and practical strategy for the construction of various keto-substituted isoxazolidines via one-pot three-component reaction of easily accessible, safer and more stable sulfoxonium ylides, nitrosoarenes and olefins is described.

Isocyanide-based three component reaction for synthesis of highly cyano substituted furan derivatives

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26783-26790 ◽  
Author(s):  
Hamid Reza Safaei ◽  
Farbod Dehbozorgi
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Furan Derivatives ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction

A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions.

scholarly journals A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 3031 ◽  
Author(s):  
Xiaodong Tang ◽  
Songlei Zhu ◽  
Ying Ma ◽  
Ren Wen ◽  
Lanqi Cen ◽  
...  
Keyword(s):  
Environmentally Benign ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
Dicarbonyl Compounds ◽  
Pyrrole Derivatives ◽  
Three Component Reaction ◽  
High Yields ◽  
Operational Simplicity

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

N-Methyl nitrones as substrates for access to N-aryl isoxazolidines via catalyst-free one-pot three-component reaction with nitrosoarenes and olefins

2021 ◽  
Author(s):  
Pingan Zhai ◽  
Wenhui Li ◽  
Jianying Lin ◽  
Shuangping Huang ◽  
Wenchao Gao ◽  
...  
Keyword(s):  
One Pot ◽  
Catalyst Free ◽  
Three Component Reaction

N-Methyl nitrones bearing wider scope are used as starting materials to construct various N-aryl isoxazolidines instead of N-methyl isoxazolidines or N−H 1,3-oxazinanes via catalyst-free one-pot three-component reaction with nitrosoarenes and...

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