ChemInform Abstract: An Asymmetric Assembly of Spirooxindole Dihydropyranones Through a Direct Enantioselective Organocatalytic Vinylogous Aldol-Cyclization Cascade Reaction of 3-Alkylidene Oxindoles with Isatins.

ChemInform ◽  
2016 ◽  
Vol 47 (23) ◽  
Author(s):  
Jeng-Liang Han ◽  
Chia-Hao Chang
Keyword(s):  
Cascade Reaction ◽  
Aldol Cyclization

ChemInform Abstract: Enantioselective Direct Vinylogous Aldol-Cyclization Cascade Reaction Between β,γ-Unsaturated Amides and o-Quinones.

ChemInform ◽  
2016 ◽  
Vol 47 (46) ◽  
Author(s):  
Yu Jiang ◽  
Jun-Hao Fu ◽  
Tian-Ze Li ◽  
Feng Sha ◽  
Xin-Yan Wu
Keyword(s):  
Cascade Reaction ◽  
Aldol Cyclization

One-pot asymmetric synthesis of a hexahydrophenanthridine scaffold containing five stereocenters via an organocatalytic quadruple-cascade reaction

2021 ◽  
Author(s):  
Xiao-Long Zhang ◽  
Kai-Xiang Feng ◽  
Jian-Liang Hu ◽  
Qiao-Yu Shen ◽  
Wang-Sheng Huang ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Cascade Reaction ◽  
One Pot ◽  
Unsaturated Aldehydes ◽  
Aldol Cyclization

An organocatalytic enantioselective aza-Michael-Michael-Michael/aldol cyclization quadruple-cascade reaction of 2-amino-β-nitrostyrenes and α,β-unsaturated aldehydes has been developed for the construction of fully substituted hexahydrophenanthridine.

Catalytic cascade aldol–cyclization of tertiary ketone enolates for enantioselective synthesis of keto-esters with a C–F quaternary stereogenic center

2016 ◽  
Vol 14 (30) ◽  
pp. 7295-7303 ◽  
Author(s):  
Wanxing Sha ◽  
Lijun Zhang ◽  
Wenzhong Zhang ◽  
Haibo Mei ◽  
Vadim A. Soloshonok ◽  
...  
Keyword(s):  
Cascade Reaction ◽  
Enantioselective Synthesis ◽  
Keto Esters ◽  
Aldol Cyclization ◽  
Ketone Enolates ◽  
Stereogenic Center

The first enantioselective catalytic aldol–cyclization cascade reaction of detrifluoroacetylatively in situ generated tertiary enolates with methyl 2-formylbenzoate is reported.

Enantioselective organocatalytic vinylogous aldol−cyclization cascade reaction of 3-alkylidene oxindoles with o-quinones

2021 ◽  
Author(s):  
Yun-Jie Tsou ◽  
Ren-You Guan ◽  
Jeng-Liang Han
Keyword(s):  
Broad Spectrum ◽  
Cascade Reaction ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
Aldol Cyclization

Spirocyclic o-quinone analogues showed a broad spectrum of applications as biologically active compounds. We herein reported the chiral bifunctional-squaramide catalysed asymmetric vinylogous aldol−cyclization cascade reaction between 3-alkylidene oxindoles and o-quinones....

An asymmetric assembly of spirooxindole dihydropyranones through a direct enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction of 3-alkylidene oxindoles with isatins

2016 ◽  
Vol 52 (11) ◽  
pp. 2322-2325 ◽  
Author(s):  
Jeng-Liang Han ◽  
Chia-Hao Chang
Keyword(s):  
Cascade Reaction ◽  
Aldol Cyclization

An unexpected enantioselective organocatalytic vinylogous aldol-cyclization cascade reaction generating dihydropyranones in good to excellent yields with high enantioselectivities.

Highly chemo- and enantioselective vinylogous aldol/cyclization cascade reaction to construct chiral 5,6-dihydropyran-2-ones

Tetrahedron ◽  
2018 ◽  
Vol 74 (27) ◽  
pp. 3557-3563 ◽  
Author(s):  
Zhen-Guo Zhang ◽  
Jun-Hao Fu ◽  
Feng Sha ◽  
Xin-Yan Wu
Keyword(s):  
Cascade Reaction ◽  
Aldol Cyclization

Enantioselective direct vinylogous aldol-cyclization cascade reaction between β,γ-unsaturated amides and o-quinones

2016 ◽  
Vol 14 (27) ◽  
pp. 6435-6441 ◽  
Author(s):  
Yu Jiang ◽  
Jun-Hao Fu ◽  
Tian-Ze Li ◽  
Feng Sha ◽  
Xin-Yan Wu
Keyword(s):  
Cascade Reaction ◽  
Aldol Cyclization

The first enantioselective vinylogous reaction with 1,2-dikeones as aldol donors has been developed to provide chiral spirocyclic dihydropyranones.

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