ChemInform Abstract: Efficient Synthesis of Octahydrophenanthrene Derivatives with Mild Cascade Reactions of Isochromenylium Tetrafluoroborates and Bifunctional Styrenes.

ChemInform ◽  
2015 ◽  
Vol 46 (45) ◽  
pp. no-no
Author(s):  
Lei Mo ◽  
Lin-Lin Wu ◽  
Shaozhong Wang ◽  
Zhu-Jun Yao
2014 ◽  
Vol 20 (33) ◽  
pp. 10214-10219 ◽  
Author(s):  
Itaru Nakamura ◽  
Yoshinori Sato ◽  
Keisuke Takeda ◽  
Masahiro Terada

2016 ◽  
Vol 52 (9) ◽  
pp. 1942-1944 ◽  
Author(s):  
Jing-Jing Wu ◽  
Yong Shi ◽  
Wei-Sheng Tian

Herein, we describe an efficient synthesis of C17α-OH-tigogenin, which is the aglycon of aspafiliosides E and F. The synthesis features three cascade processes, which involve the iodo-lactonization of furostan-26-acid, a cascade hydrolysis/intramolecular SN2 process, and a cascade intramolecular redox-ketalization process.


2017 ◽  
Vol 53 (28) ◽  
pp. 4002-4005 ◽  
Author(s):  
Yan He ◽  
Fang Wang ◽  
Xinying Zhang ◽  
Xuesen Fan

A novel and efficient synthesis of tetrahydropyridine-, dihydropyrrole-, and tetrahydroazepine-3-carboxylates via cascade reactions of cyclic amines with CO and alcohols is presented. To our knowledge, this should be the first example in which functionalized N-heterocycles were prepared through Pd-catalyzed C(sp3)–H dehydrogenation and C(sp2)–H carbonylation of cyclic amines.


2014 ◽  
Vol 50 (17) ◽  
pp. 2196-2198 ◽  
Author(s):  
Lin Qiu ◽  
Xin Guo ◽  
Chaoqun Ma ◽  
Huang Qiu ◽  
Shunying Liu ◽  
...  

Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.


ChemInform ◽  
2013 ◽  
Vol 44 (23) ◽  
pp. no-no
Author(s):  
Jun Jiang ◽  
Xiaoyu Guan ◽  
Shunying Liu ◽  
Baiyan Ren ◽  
Xiaochu Ma ◽  
...  

2020 ◽  
Vol 56 (61) ◽  
pp. 8699-8702
Author(s):  
Xue-Qiang Chu ◽  
Ting Xie ◽  
Ya-Wen Wang ◽  
Xiang-Rui Li ◽  
Weidong Rao ◽  
...  

Cascade reactions of α-perfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides that allowed the efficient synthesis of fluoroalkylated di(hetero)aryl sulfide derivatives under transition metal-free conditions were developed.


ChemInform ◽  
2014 ◽  
Vol 45 (20) ◽  
pp. no-no
Author(s):  
Lin Qiu ◽  
Xin Guo ◽  
Chaoqun Ma ◽  
Huang Qiu ◽  
Shunying Liu ◽  
...  

Author(s):  
Linghua Zhang ◽  
Jie Zhao ◽  
Yuqin Jiang ◽  
Xinying Zhang ◽  
Xuesen Fan

Presented herein is a novel and efficient synthesis of the synthetically and biologically attractive tetracyclic indenopyrazolopyrazolone derivatives through the cascade reactions of aryl azomethine imines with propargyl alcohols. Mechanistically, the...


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