ChemInform Abstract: Transition-Metal Free Synthesis of Diaryl Vinyl Selenides: A Simple Synthetic Approach with High Selectivity.

ChemInform ◽  
2014 ◽  
Vol 45 (37) ◽  
pp. no-no
Author(s):  
Balaji Mohan ◽  
Sori Hwang ◽  
Hyunje Woo ◽  
Kang Hyun Park
Keyword(s):  
Transition Metal ◽  
High Selectivity ◽  
Synthetic Approach ◽  
Metal Free

Transition-metal free synthesis of diaryl vinyl selenides: a simple synthetic approach with high selectivity

Tetrahedron ◽  
2014 ◽  
Vol 70 (17) ◽  
pp. 2699-2702 ◽  
Author(s):  
Balaji Mohan ◽  
Sori Hwang ◽  
Hyunje Woo ◽  
Kang Hyun Park
Keyword(s):  
Transition Metal ◽  
High Selectivity ◽  
Synthetic Approach ◽  
Metal Free

scholarly journals A practical and sustainable protocol for direct amidation of unactivated esters under transition-metal-free and solvent-free conditions

2021 ◽  
Author(s):  
Rui Zhang ◽  
Wei-Zhong Yao ◽  
Liang Qian ◽  
Wei Sang ◽  
Ye Yuan ◽  
...  
Keyword(s):  
Transition Metal ◽  
Solvent Free ◽  
Synthetic Approach ◽  
Metal Free ◽  
Solvent Free Conditions ◽  
Direct Amidation

In this paper, a NaOtBu-mediated synthetic approach was developed for direct amidation of unactivated esters with amines under transition-metal-free and solvent-free conditions, affording a series of amides in good to...

Visible Light Mediated Synthesis of 6H-Benzo[c]chromenes: Transition-Metal-Free Intramolecular Direct C-H Arylation

2021 ◽  
Author(s):  
Micaela Heredia ◽  
Marcelo Puiatti ◽  
Roberto A. Rossi ◽  
María E. Budén
Keyword(s):  
Transition Metal ◽  
Visible Light ◽  
Synthetic Approach ◽  
Metal Free ◽  
Benzyl Ethers ◽  
Phenyl Ethers ◽  
Chromene Ring

A synthetic approach towards 6H-benzo[c]chromene ring under visible light and transition-metal-free conditions has been developed. Benzochromenes are synthesized from the corresponding (2-halobenzyl) phenyl ethers or (2-halophenyl) benzyl ethers using KOtBu...

scholarly journals Vicinal difunctionalization of carbon–carbon double bond for the platform synthesis of trifluoroalkyl amines

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Ferenc Béke ◽  
Ádám Mészáros ◽  
Ágnes Tóth ◽  
Bence Béla Botlik ◽  
Zoltán Novák
Keyword(s):  
Double Bond ◽  
Transition Metal ◽  
High Efficiency ◽  
Chemical Nature ◽  
Synthetic Approach ◽  
Selective Synthesis ◽  
Reaction Conditions ◽  
Metal Free ◽  
Amine Compounds ◽  
Broad Scale

AbstractRegioselective vicinal diamination of carbon–carbon double bonds with two different amines is a synthetic challenge under transition metal-free conditions, especially for the synthesis of trifluoromethylated amines. However, the synthesis of ethylene diamines and fluorinated amine compounds is demanded, especially in the pharmaceutical sector. Herein, we demonstrate that the controllable double nucleophilic functionalization of an activated alkene synthon, originated from a trifluoropropenyliodonium salt with two distinct nucleophiles, enables the selective synthesis of trifluoromethylated ethylene amines and diamines on broad scale with high efficiency under mild reaction conditions. Considering the chemical nature of the reactants, our synthetic approach brings forth an efficient methodology and provides versatile access to highly fluorinated amines.

scholarly journals Iodine-mediated C–N and N–N bond formation: a facile one-pot synthetic approach to 1,2,3-triazoles under metal-free and azide-free conditions

RSC Advances ◽  
2019 ◽  
Vol 9 (46) ◽  
pp. 27021-27031 ◽  
Author(s):  
Geeta Sai Mani ◽  
Kavitha Donthiboina ◽  
Siddiq Pasha Shaik ◽  
Nagula Shankaraiah ◽  
Ahmed Kamal
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Synthetic Approach ◽  
One Pot ◽  
Metal Free ◽  
Novel Strategy

A novel strategy towards the synthesis of 1,4-disubstituted 1,2,3-triazoles via C–N and N–N bond formation has been demonstrated under transition metal-free and azide-free conditions.

scholarly journals Transition metal-free oxidative and deoxygenative C–H/C–Li cross-couplings of 2H-imidazole 1-oxides with carboranyl lithium as an efficient synthetic approach to azaheterocyclic carboranes

2018 ◽  
Vol 14 ◽  
pp. 2618-2626 ◽  
Author(s):  
Lidia A Smyshliaeva ◽  
Mikhail V Varaksin ◽  
Pavel A Slepukhin ◽  
Oleg N Chupakhin ◽  
Valery N Charushin
Keyword(s):  
Transition Metal ◽  
Nucleophilic Substitution ◽  
Advanced Materials ◽  
Synthetic Approach ◽  
Nucleophilic Substitution Of Hydrogen ◽  
One Pot ◽  
Metal Free

The direct C–H functionalization methodology has first been applied to perform transition metal-free C–H/C–Li cross-couplings of 2H-imidazole 1-oxides with carboranyllithium. This atom- and step-economical approach, based on one-pot reactions of nucleophilic substitution of hydrogen (SN H) in non-aromatic azaheterocycles, affords novel imidazolyl-modified carboranes of two types (N-oxides and their deoxygenative analogues), which are particularly of interest in the design of advanced materials.

Transition-metal-free synthesis of indolizines via [3 + 2]-annulation from α-bromoenals and 2-substituted azaarenes

2017 ◽  
Vol 4 (11) ◽  
pp. 2119-2123 ◽  
Author(s):  
Yuan Liu ◽  
Yang Yu ◽  
Yiwei Fu ◽  
Yonghai Liu ◽  
Lei Shi ◽  
...  
Keyword(s):  
Transition Metal ◽  
Synthetic Approach ◽  
One Pot ◽  
Metal Free

A transition-metal-free “one-pot” synthetic approach for the synthesis of indolizines from α-bromo-substituted enals and simple 2-substituted azaarenes has been developed.

Transition-metal-free catalytic hydroboration reduction of amides to amines

2020 ◽  
Vol 7 (21) ◽  
pp. 3515-3520
Author(s):  
Wubing Yao ◽  
Jiali Wang ◽  
Aiguo Zhong ◽  
Shiliang Wang ◽  
Yinlin Shao
Keyword(s):  
Transition Metal ◽  
Selective Catalytic Reduction ◽  
Catalytic Reduction ◽  
Value Added ◽  
Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

2021 ◽  
Author(s):  
Fengqian Zhao ◽  
Xiao-Feng Wu
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

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