ChemInform Abstract: Nature-Like Synthetic Alkyl Branched Chain Glycolipids: Chemical Structure and Self-Assembly Properties

ChemInform ◽  
2012 ◽  
Vol 43 (15) ◽  
pp. no-no
Author(s):  
Rauzah Hashim ◽  
Akihiko Sugimura ◽  
Hiroyuki Minamikawa ◽  
Thorsten Heidelberg
Keyword(s):  
Self Assembly ◽  
Chemical Structure ◽  
Branched Chain

Nature-likesynthetic alkyl branched-chain glycolipids: a review on chemical structure and self-assembly properties

2012 ◽  
Vol 39 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Rauzah Hashim ◽  
Akihiko Sugimura ◽  
Hiroyuki Minamikawa ◽  
Thorsten Heidelberg
Keyword(s):  
Self Assembly ◽  
Chemical Structure ◽  
Branched Chain

Lyotropic Phase Behaviour and Structural Parameters of Monosaccharide and Disaccharide Guerbet Branched-Chain β-D-Glycosides

2014 ◽  
Vol 895 ◽  
pp. 111-115 ◽  
Author(s):  
Hairul A.A. Hamid ◽  
Rauzah Hashim ◽  
John M. Seddon ◽  
Nicholas J. Brooks
Keyword(s):  
Self Assembly ◽  
Room Temperature ◽  
Structural Parameters ◽  
Phase Behaviour ◽  
Hydroxyl Groups ◽  
X Ray Diffraction ◽  
X Ray ◽  
Branched Chain ◽  
Optical Polarizing Microscopy ◽  
Water Contents

The phase behaviour and self-assembly structural parameters of a pair of monosaccharide and disaccharide Guerbet branched-chain β-D-glycosides, namely 2-octyldodecyl β-D-glucoside (β-Glc-C12C8) and 2-octyldodecyl β-D-maltoside (β-Mal-C12C8), have been studied by means of optical polarizing microscopy (OPM) and small-angle X-ray diffraction at room temperature (25°C). These compounds are sugar-based glycolipid surfactants having a total chain length of C20, and differ based on the increasing number of hydroxyl groups of the sugar headgroup (glucose and maltose). The repeat spacings obtained by X-ray diffraction as a function of water content have been used to determine the limiting hydration for the two glycosides. At room temperature, β-Glc-C12C8 and β-Mal-C12C8 have limiting hydrations of 22 wt% and 25 wt%, corresponding to 8 10 and 10 12 water molecules per glycoside, respectively. At all water contents between 5 and 29 wt % water, these compounds adopt inverse hexagonal (HII) or fluid lamellar (Lα) phases. The structural parameters of these phases have been determined from the diffraction data, from the X-ray repeat spacings, densities and concentration of the glycosides.

Self-Assembly of Squalene-Based Nucleolipids: Relating the Chemical Structure of the Bioconjugates to the Architecture of the Nanoparticles

Langmuir ◽  
2013 ◽  
Vol 29 (48) ◽  
pp. 14795-14803 ◽  
Author(s):  
Elise Lepeltier ◽  
Claudie Bourgaux ◽  
Véronique Rosilio ◽  
Jacques H. Poupaert ◽  
Florian Meneau ◽  
...  
Keyword(s):  
Self Assembly ◽  
Chemical Structure

Molecular dynamics of anhydrous glycolipid self-assembly in lamellar and hexagonal phases

2016 ◽  
Vol 18 (22) ◽  
pp. 15182-15190 ◽  
Author(s):  
T. S. Velayutham ◽  
H. S. Nguan ◽  
B. K. Ng ◽  
W. C. Gan ◽  
V. Manickam Achari ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Liquid Crystal ◽  
Self Assembly ◽  
Crystal Phases ◽  
Branched Chain ◽  
Liquid Crystal Phases

The molecular dynamics of a synthetic branched chain glycolipid, 2-decyl-tetradecyl-β-d-maltoside (C14-10G2), in smectic and columnar liquid crystal phases.

STM investigation of the dependence of alkane and alkane (C18H38, C19H40) derivatives self-assembly on molecular chemical structure on HOPG surface

2008 ◽  
Vol 602 (6) ◽  
pp. 1256-1266 ◽  
Author(s):  
Qing Chen ◽  
Hui-Juan Yan ◽  
Cun-Ji Yan ◽  
Ge-Bo Pan ◽  
Li-Jun Wan ◽  
...  
Keyword(s):  
Self Assembly ◽  
Chemical Structure

scholarly journals Synthesis and Characterization of an Amphiphilic Linoleic Acid-g-Quaternary Chitosan with Low Toxicity

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Xiaobin Fang ◽  
Yingqi Xu ◽  
Jinming Zhang ◽  
Xianghong Lu ◽  
Yitao Wang ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Chemical Structure ◽  
H Nmr ◽  
Low Toxicity ◽  
Low Cytotoxicity ◽  
Average Size ◽  
Novel Drug

A novel amphiphilic derivative of chitosan, namely, a linoleic acid-g-quaternary chitosan (LA-g-QC), was designed and synthesized as low toxic material for biomedical applications in this study. The chemical structure of LA-g-QC was characterized by Fourier transform infrared spectroscopy (FTIR),1H nuclear magnetic resonance (1H-NMR), and elemental analysis. LA-g-QC could form nanosized micelles with self-assembly, which was confirmed by the results of critical micelle concentration (CMC) via fluorescence spectroscopy. The average size of LA-g-QC was 140 nm and its zeta potential was approximately +35.50 mV. CMC value was 31.00 mg/mL. Furthermore, LA-g-QC micelles, at final concentrations between 0.94 μg/mL and 30 μg/mL, did not inhibit the proliferation of HepG2 or SMMC 7721 cell lines. Taken together, LA-g-QC has low cytotoxicity and high potential for the preparation of novel drug-delivery micelles.

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