ChemInform Abstract: Sequential Catalytic Process: Synthesis of Quinoline Derivatives by AuCl3/CuBr-Catalyzed Three-Component Reaction of Aldehydes, Amines, and Alkynes.

ChemInform ◽  
2008 ◽  
Vol 39 (38) ◽  
Author(s):  
Fengping Xiao ◽  
Yulin Chen ◽  
Yu Liu ◽  
Jianbo Wang
Keyword(s):  
Catalytic Process ◽  
Process Synthesis ◽  
Quinoline Derivatives ◽  
Three Component Reaction

Synthesis of substituted 4-hydroxyalkyl-quinoline derivatives by a three-component reaction using CuCl/AuCl as sequential catalysts

2018 ◽  
Vol 5 (3) ◽  
pp. 434-441 ◽  
Author(s):  
Kun-Ming Jiang ◽  
Jing-An Kang ◽  
Yi Jin ◽  
Jun Lin
Keyword(s):  
New Method ◽  
Quinoline Derivatives ◽  
Three Component Reaction

A new method to construct 4-hydroxyalkyl-quinoline derivatives is described via Cu(i) and Au(i) sequential catalyzed cyclization of anilines with aldehyde derivatives and aliphatic alkynes, respectively.

MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives

2020 ◽  
Vol 44 (20) ◽  
pp. 8614-8620 ◽  
Author(s):  
Song-Tao Xiao ◽  
Cui-Ting Ma ◽  
Jia-Qi Di ◽  
Zhan-Hui Zhang
Keyword(s):  
Aromatic Amines ◽  
Recyclable Catalyst ◽  
Solvent Free ◽  
Quinoline Derivatives ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Three Component Reaction

An approach was developed for the synthesis of 2,4-disubstituted quinoline derivatives via a one pot three-component reaction of aromatic amines, aldehydes and alkynes catalyzed by MOF-5 under solvent-free conditions.

An efficient and novel protocol for the synthesis of spiro[1,3]oxazino[5,6-c]quinoline derivatives by one-pot, three-component reaction

2019 ◽  
Vol 46 (1) ◽  
pp. 165-177 ◽  
Author(s):  
Maryam Aslanpanjeh ◽  
Ahmad Poursattar Marjani ◽  
Jabbar Khalafy ◽  
Nasser Etivand
Keyword(s):  
Quinoline Derivatives ◽  
One Pot ◽  
Three Component Reaction

Indium promoted C(sp3)–P bond formation by the Domino A3-coupling method – a combined experimental and computational study

2021 ◽  
Author(s):  
Suman Das ◽  
Parveen Rawal ◽  
Jayeeta Bhattacharjee ◽  
Ajitrao Devadkar ◽  
Kuntal Pal ◽  
...  
Keyword(s):  
Room Temperature ◽  
Computational Study ◽  
Bond Formation ◽  
Catalytic Reactions ◽  
Coupling Method ◽  
Catalytic Process ◽  
Mechanistic Studies ◽  
One Pot ◽  
Three Component Reaction ◽  
A3 Coupling

An efficient catalytic process for the synthesis of α-aminophosphonates is developed by a one-pot three-component reaction in the presence of In complexes at room temperature. DFT based mechanistic studies of the catalytic reactions are reported.

scholarly journals An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
M. Mamaghani ◽  
K. Tabatabaeian ◽  
R. Araghi ◽  
A. Fallah ◽  
R. Hossein Nia
Keyword(s):  
Ethylene Glycol ◽  
Ultrasonic Irradiation ◽  
Reaction Times ◽  
Quinoline Derivatives ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Catalyst Free ◽  
Three Component Reaction

In this report, synthesis of indenopyrido[2,3-d]pyrimidine and pyrimido[4,5-b]quinoline derivatives was investigated via one-pot three-component reaction between 6-amino-2-(alkylthio)-pyrimidin-4(3H)one, 1,3-indanedione, or 1,3-cyclohexadione and arylaldehyde under ultrasonic irradiation in ethylene glycol as solvent at 65°C. In these reactions fused pyrimidine derivatives were synthesized with high to excellent yields (82–97%) and short reaction times (10–33 min).

Distribution of R- and S-Process Elements in the Galactic Halo

1988 ◽  
Vol 132 ◽  
pp. 501-506
Author(s):  
C. Sneden ◽  
C. A. Pilachowski ◽  
K. K. Gilroy ◽  
J. J. Cowan
Keyword(s):  
Heavy Element ◽  
Galactic Halo ◽  
Low Noise ◽  
Heavy Elements ◽  
Process Synthesis ◽  
Element Abundances ◽  
Halo Stars ◽  
Abundance Patterns ◽  
R Process ◽  
Process Elements

Current observational results for the abundances of the very heavy elements (Z>30) in Population II halo stars are reviewed. New high resolution, low noise spectra of many of these extremely metal-poor stars reveal general consistency in their overall abundance patterns. Below Galactic metallicities of [Fe/H] Ã −2, all of the very heavy elements were manufactured almost exclusively in r-process synthesis events. However, there is considerable star-to-star scatter in the overall level of very heavy element abundances, indicating the influence of local supernovas on element production in the very early, unmixed Galactic halo. The s-process appears to contribute substantially to stellar abundances only in stars more metal-rich than [Fe/H] Ã −2.

Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1

2019 ◽  
Vol 476 (21) ◽  
pp. 3227-3240 ◽  
Author(s):  
Shanshan Wang ◽  
Yanxiang Zhao ◽  
Long Yi ◽  
Minghe Shen ◽  
Chao Wang ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Conformational Changes ◽  
Magnaporthe Oryzae ◽  
Structural Information ◽  
Complex Structure ◽  
Critical Role ◽  
Catalytic Process ◽  
Structural Basis ◽  
Salt Bridges ◽  
Terminal Domain

Trehalose-6-phosphate (T6P) synthase (Tps1) catalyzes the formation of T6P from UDP-glucose (UDPG) (or GDPG, etc.) and glucose-6-phosphate (G6P), and structural basis of this process has not been well studied. MoTps1 (Magnaporthe oryzae Tps1) plays a critical role in carbon and nitrogen metabolism, but its structural information is unknown. Here we present the crystal structures of MoTps1 apo, binary (with UDPG) and ternary (with UDPG/G6P or UDP/T6P) complexes. MoTps1 consists of two modified Rossmann-fold domains and a catalytic center in-between. Unlike Escherichia coli OtsA (EcOtsA, the Tps1 of E. coli), MoTps1 exists as a mixture of monomer, dimer, and oligomer in solution. Inter-chain salt bridges, which are not fully conserved in EcOtsA, play primary roles in MoTps1 oligomerization. Binding of UDPG by MoTps1 C-terminal domain modifies the substrate pocket of MoTps1. In the MoTps1 ternary complex structure, UDP and T6P, the products of UDPG and G6P, are detected, and substantial conformational rearrangements of N-terminal domain, including structural reshuffling (β3–β4 loop to α0 helix) and movement of a ‘shift region' towards the catalytic centre, are observed. These conformational changes render MoTps1 to a ‘closed' state compared with its ‘open' state in apo or UDPG complex structures. By solving the EcOtsA apo structure, we confirmed that similar ligand binding induced conformational changes also exist in EcOtsA, although no structural reshuffling involved. Based on our research and previous studies, we present a model for the catalytic process of Tps1. Our research provides novel information on MoTps1, Tps1 family, and structure-based antifungal drug design.

Substituted Amides of Quinoline Derivatives: Preparation and Their Photosynthesis-inhibiting Activity

2006 ◽  
Author(s):  
Robert Musiol ◽  
Josef Jampilek ◽  
Katarina Kralova ◽  
Dominik Tabak ◽  
Barbara Podeszwa ◽  
...  
Keyword(s):  
Inhibiting Activity ◽  
Quinoline Derivatives
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