Synthesis of substituted 4-hydroxyalkyl-quinoline derivatives by a three-component reaction using CuCl/AuCl as sequential catalysts

2018 ◽  
Vol 5 (3) ◽  
pp. 434-441 ◽  
Author(s):  
Kun-Ming Jiang ◽  
Jing-An Kang ◽  
Yi Jin ◽  
Jun Lin
Keyword(s):  
New Method ◽  
Quinoline Derivatives ◽  
Three Component Reaction

A new method to construct 4-hydroxyalkyl-quinoline derivatives is described via Cu(i) and Au(i) sequential catalyzed cyclization of anilines with aldehyde derivatives and aliphatic alkynes, respectively.

MOF-5 as a highly efficient and recyclable catalyst for one pot synthesis of 2,4-disubstituted quinoline derivatives

2020 ◽  
Vol 44 (20) ◽  
pp. 8614-8620 ◽  
Author(s):  
Song-Tao Xiao ◽  
Cui-Ting Ma ◽  
Jia-Qi Di ◽  
Zhan-Hui Zhang
Keyword(s):  
Aromatic Amines ◽  
Recyclable Catalyst ◽  
Solvent Free ◽  
Quinoline Derivatives ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Three Component Reaction

An approach was developed for the synthesis of 2,4-disubstituted quinoline derivatives via a one pot three-component reaction of aromatic amines, aldehydes and alkynes catalyzed by MOF-5 under solvent-free conditions.

An efficient and novel protocol for the synthesis of spiro[1,3]oxazino[5,6-c]quinoline derivatives by one-pot, three-component reaction

2019 ◽  
Vol 46 (1) ◽  
pp. 165-177 ◽  
Author(s):  
Maryam Aslanpanjeh ◽  
Ahmad Poursattar Marjani ◽  
Jabbar Khalafy ◽  
Nasser Etivand
Keyword(s):  
Quinoline Derivatives ◽  
One Pot ◽  
Three Component Reaction

Silver-catalyzed geminal aminofluorination of diazoketones with anilines and N-fluorobenzenesulphonimide

2017 ◽  
Vol 4 (4) ◽  
pp. 529-533 ◽  
Author(s):  
Jun Huang ◽  
Linyong Li ◽  
Haoguo Chen ◽  
Tiebo Xiao ◽  
Yuwei He ◽  
...  
Keyword(s):  
Nitrogen Source ◽  
New Method ◽  
Diazo Compounds ◽  
Three Component Reaction

A silver-catalyzed three-component reaction of diazoketones, anilines and NFSI is developed. The reaction provides a new method for gem-aminofluorination of acceptor diazo compounds with aniline as the nitrogen source and NFSI as the fluorine source.

scholarly journals Three-component synthesis, utilization and biological activity of phosphinoyl-functionalized isoindolinones

2021 ◽  
Author(s):  
Nóra Popovics-Tóth ◽  
Bettina Rávai ◽  
Ádám Tajti ◽  
Bence Varga ◽  
Péter Bagi ◽  
...  
Keyword(s):  
Biological Activity ◽  
Phosphorus Atom ◽  
New Method ◽  
Primary Amines ◽  
One Pot ◽  
Three Component Reaction ◽  
The One

A new method for the synthesis of 3-oxoisoindolin-1-ylphosphine oxides bearing same or different substituents on the phosphorus atom is described. The one-pot three-component reaction of 2-formylbenzoic acid, primary amines and...

scholarly journals An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
M. Mamaghani ◽  
K. Tabatabaeian ◽  
R. Araghi ◽  
A. Fallah ◽  
R. Hossein Nia
Keyword(s):  
Ethylene Glycol ◽  
Ultrasonic Irradiation ◽  
Reaction Times ◽  
Quinoline Derivatives ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Catalyst Free ◽  
Three Component Reaction

In this report, synthesis of indenopyrido[2,3-d]pyrimidine and pyrimido[4,5-b]quinoline derivatives was investigated via one-pot three-component reaction between 6-amino-2-(alkylthio)-pyrimidin-4(3H)one, 1,3-indanedione, or 1,3-cyclohexadione and arylaldehyde under ultrasonic irradiation in ethylene glycol as solvent at 65°C. In these reactions fused pyrimidine derivatives were synthesized with high to excellent yields (82–97%) and short reaction times (10–33 min).

Trifluoroacetic acid catalyzed thiophenylmethylation and thioalkylmethylation of lactams and phenols via domino three-component reaction in water

RSC Advances ◽  
2014 ◽  
Vol 4 (27) ◽  
pp. 14081-14088 ◽  
Author(s):  
Ramesh Mudududdla ◽  
Rohit Sharma ◽  
Santosh K. Guru ◽  
Manoj Kushwaha ◽  
Ajai P. Gupta ◽  
...  
Keyword(s):  
Trifluoroacetic Acid ◽  
New Method ◽  
Three Component Reaction ◽  
Acid Catalyzed ◽  
Reaction In Water

A new method for thiophenylmethylation and thioalkylmethylation of lactams and phenols has been described.

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