FR258900, a Novel Glycogen Phosphorylase Inhibitor Isolated from Fungus No.138354. Part 2. Antihyperglycemic Effects in Diabetic Animal Models.

ChemInform ◽  
2006 ◽  
Vol 37 (3) ◽  
Author(s):  
Shigetada Furukawa ◽  
Kana Murakami ◽  
Motoaki Nishikawa ◽  
Osamu Nakayama ◽  
Motohiro Hino
2019 ◽  
Vol 63 (15) ◽  
pp. 1801058 ◽  
Author(s):  
Aruna Gorusupudi ◽  
Fu‐Yen Chang ◽  
Kelly Nelson ◽  
Gregory S. Hageman ◽  
Paul S. Bernstein

2021 ◽  
Vol 331 ◽  
pp. e100
Author(s):  
C. Sena ◽  
D. Carvalho ◽  
A. Pereira ◽  
M. Queiroz ◽  
R. Seiça

ChemInform ◽  
2010 ◽  
Vol 41 (31) ◽  
pp. no-no
Author(s):  
Z. Czako ◽  
T. Docsa ◽  
P. Gergely ◽  
L. Luhasz ◽  
S. Antus

1978 ◽  
Vol 74 (5) ◽  
pp. 1082 ◽  
Author(s):  
K. Ramaswamy ◽  
M.A Peterson ◽  
G.C. Gerritsen

2016 ◽  
Vol 120 ◽  
pp. S182-S183
Author(s):  
NaYoung Lee ◽  
Hyun Ah Ko ◽  
Yu Ji Kim ◽  
Kyung Ae Lee ◽  
Heung Yong Jin ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 629 ◽  
Author(s):  
Ling-Shan Tse ◽  
Po-Lin Liao ◽  
Chi-Hao Tsai ◽  
Ching-Hao Li ◽  
Jiunn-Wang Liao ◽  
...  

Hedychium coronarium has a long history of use worldwide as a food and in folk medicine. In this study, we aimed to investigate the effect of an aqueous extract of H. coronarium leaves (HC) on type 2 diabetes mellitus (T2DM). Two types of animal models were used in this study: Streptozotocin (STZ)-induced T2DM (Wistar rats; N = 8) and C57BKSdb/db mice (N = 5). After treatment with HC for 28 days, glucose tolerance improved in both of the diabetic animal models. As significant effects were shown after 14 days of treatment in the STZ-induced T2DM model, we carried out the experiments with it. After 28 days of treatment with HC, the levels of cholesterol, triglyceride, high-density lipoprotein, and low-density lipoprotein were significantly improved in the STZ-induced T2DM model. The lesions degree of islet β-cells was decreased after the HC treatment. Although the insulin level increased moderately, the aldosterone level was significantly decreased in the HC-treated groups, suggesting that aldosterone might play an important role in this effect. In summary, HC is a natural product and it is worth exploring its effect on T2DM.


PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e30555 ◽  
Author(s):  
Yin Liang ◽  
Kenji Arakawa ◽  
Kiichiro Ueta ◽  
Yasuaki Matsushita ◽  
Chiaki Kuriyama ◽  
...  

2002 ◽  
Vol 1569 (1-3) ◽  
pp. 75-80 ◽  
Author(s):  
Mark H Mooney ◽  
Yasser H.A Abdel-Wahab ◽  
Aine M McKillop ◽  
Finbarr P.M O’Harte ◽  
Peter R Flatt

Sign in / Sign up

Export Citation Format

Share Document