ChemInform Abstract: New Antifungal Agents: Synthesis and Biological Activity

ChemInform ◽  
2010 ◽  
Vol 24 (46) ◽  
pp. no-no
Author(s):  
V. GIRIJAVALLABHAN ◽  
A. K. GANGULY ◽  
A. K. SAKSENA ◽  
A. B. COOPER ◽  
R. LOVEY ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Agents

scholarly journals Recovery of pure C-phycoerythrin from a limestone drought tolerant cyanobacterium Nostoc sp. and evaluation of its biological activity

2020 ◽  
pp. 115-128
Author(s):  
Bahareh Nowruzi ◽  
Hossein Fahimi ◽  
Adriana Sturion Lorenzi
Keyword(s):  
Biological Activity ◽  
Antifungal Agents ◽  
Extreme Environments ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Biotechnological Applications ◽  
Drought Tolerant ◽  
Drought Conditions ◽  
Antibacterial And Antifungal ◽  
First Time

Se realizó la caracterización de ficoeritrina de la cepa A5 de Nostoc sp., seguida de investigación de su actividad biológica para aplicaciones biotecnológicas. Para la extracción de ficoeritrina, el uso de tampón acetato (pH 5.1) produjo 65.04 µg mL-1, y se identificó como C-ficoeritrina. Los resultados de su actividad antioxidante sugirieron su acción como un potente eliminador de radicales libres. Además, la C-ficoeritrina de Nostoc mostró una capacidad notable como agente antibacteriano y antifúngico, con estabilidad significativa de hasta 10 días. La glucosa (4 mg mL-1) fue un buen conservante para la C-ficoeritrina a 25 y 4 ºC. Se obtuvo por primera vez una C-ficoeritrina estable de Nostoc sp. en condiciones de sequía en piedra caliza, lo que demuestra la necesidad de estudiar microorganismos de ambientes extremos. The phycoerythrin characterization from Nostoc sp. strain A5 was done, followed by investigation of its biological activity for biotechnological applications. For phycoerythrin extraction, the use of acetate buffer (pH 5.1) resulted in 65.04 µg mL-1, and C-phycoerythrin was identified. Results of its antioxidant activity suggested action as a potent free radical scavenger. In addition, Nostoc's C-phycoerythrin showed noteworthy ability for antibacterial and antifungal agents with significant stability up to 10 days. Glucose (4 mg mL-1) was a good preservative for C-phycoerythrin at 25 and 4 ºC. A stable C-phycoerythrin from Nostoc sp. was obtained for the first time from limestone drought conditions, showing the need of studying microorganisms from extreme environments.

scholarly journals Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. I. Discovery, isolation and biological activity.

1992 ◽  
Vol 45 (3) ◽  
pp. 306-312 ◽  
Author(s):  
JOSEPH O''SULLIVAN ◽  
DOUGLAS W. PHILLIPSON ◽  
DONALD R. KIRSCH ◽  
SUSAN M. FISHER ◽  
MARGARET H. LAI ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Agents

scholarly journals Sphingofungins A,B,C, and d; a new family of antifungal agents. I. Fermentation, isolation, and biological activity.

1992 ◽  
Vol 45 (6) ◽  
pp. 861-867 ◽  
Author(s):  
FRANK VANMIDDLESWORTH ◽  
ROBERT A. GIACOBBE ◽  
MARIA LOPEZ ◽  
GEORGE GARRITY ◽  
JUDITH A. BLAND ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Agents ◽  
New Family

Modeling, synthesis and biological activity of novel antifungal agents (1)

1998 ◽  
Vol 8 (14) ◽  
pp. 1819-1824 ◽  
Author(s):  
Takuo Tsukuda ◽  
Yasuhiko Shiratori ◽  
Masami Watanabe ◽  
Hitomi Ontsuka ◽  
Kazuo Hattori ◽  
...  
Keyword(s):  
Biological Activity ◽  
Antifungal Agents

scholarly journals Synthesis and Antimicrobial Characterization of Luotonin Derivatives

2020 ◽  
Vol 15 (12) ◽  
pp. 1934578X2095275
Author(s):  
Rui Zhu ◽  
Rui Guo ◽  
Ke Han ◽  
Wenying Xi ◽  
Shaojun Zheng ◽  
...  
Keyword(s):  
Biological Activity ◽  
Plant Pathogen ◽  
Antifungal Agents ◽  
Antimicrobial Activities ◽  
Lead Compounds ◽  
The Relationship ◽  
Further Development

Twenty-one novel luotonin derivatives were synthesized from 2-aminobenzamide in excellent yields. The prepared compounds, when tested against 8 strains of bacteria and many plant pathogen fungi showed diverse and promising antimicrobial activities. Notably, compounds a5, a9, b4, and b5 demonstrated good activities and might be potential lead compounds for further development as antifungal agents. The relationship between structure and biological activity is also discussed.

Discovery of Natural Product‐Based Fungicides (II): Semisynthesis and Biological Activity of Sarisan Attached 3‐Phenylisoxazolines as Antifungal Agents

2020 ◽  
Vol 17 (12) ◽  
Author(s):  
Zhiyan Liu ◽  
Jiangping Cao ◽  
Xiaoting Yan ◽  
Wanqing Cheng ◽  
Xiaoguang Wang ◽  
...  
Keyword(s):  
Biological Activity ◽  
Natural Product ◽  
Antifungal Agents
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