ChemInform Abstract: Diastereoselective Synthesis of Optically Active Pyrrolizidine and Indolizidine Ring Systems Through Intramolecular Ene Reaction.

ChemInform ◽  
2010 ◽  
Vol 22 (25) ◽  
pp. no-no
Author(s):  
S. DIKE ◽  
M. MAHALINGAM ◽  
A. KUMAR
Keyword(s):  
Optically Active ◽  
Diastereoselective Synthesis ◽  
Ring Systems ◽  
Ene Reaction

Diastereoselective Synthesis of Novel Optically Active Five Membered O- and N-heterocyclic Compounds

2012 ◽  
Vol 9 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Ervin Kovacs ◽  
Ferenc Farkas ◽  
Angelika Thurner ◽  
Aron Szollosy ◽  
Ferenc Faigl
Keyword(s):  
Heterocyclic Compounds ◽  
Optically Active ◽  
Diastereoselective Synthesis

scholarly journals Synthetic approaches to fumitremorgins. III. Synthesis of optically active pentacyclic ring systems, and their oxidation at ring C.

1989 ◽  
Vol 37 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Masako NAKAGAWA ◽  
Hiroshi FUKUSHIMA ◽  
Tomohiko KAWATE ◽  
Mitsuya HONGU ◽  
Teruaki UNE ◽  
...  
Keyword(s):  
Optically Active ◽  
Ring Systems ◽  
Synthetic Approaches

ChemInform Abstract: Diastereoselective Synthesis of Functionalized Carbazoles via a Sequential Diels-Alder/Ene Reaction Strategy.

ChemInform ◽  
2015 ◽  
Vol 46 (28) ◽  
pp. no-no
Author(s):  
Joseph Cowell ◽  
Matokah Abualnaja ◽  
Stephanie Morton ◽  
Ruth Linder ◽  
Faye Buckingham ◽  
...  
Keyword(s):  
Diels Alder ◽  
Diastereoselective Synthesis ◽  
Ene Reaction

BINOL-Al catalysed asymmetric cyclization and amplification: preparation of optically active menthol analogs

2015 ◽  
Vol 13 (20) ◽  
pp. 5817-5825 ◽  
Author(s):  
Hisanori Itoh ◽  
Hironori Maeda ◽  
Shinya Yamada ◽  
Yoji Hori ◽  
Takashi Mino ◽  
...  
Keyword(s):  
Optically Active ◽  
Ene Reaction ◽  
Aluminum Complexes

We report a highly selective asymmetric ring-closing ene reaction catalyzed by chiral aluminum complexes. Asymmetric amplification of this reaction was investigated by varying the ee of the BINOL employed in the catalyst.

scholarly journals Concise and Stereoselective Total Syntheses of Annotinolides C, D, and E

2021 ◽  
Author(s):  
Pei Qu ◽  
Scott Snyder
Keyword(s):  
Natural Products ◽  
Oxidation States ◽  
Ring Systems ◽  
Total Syntheses ◽  
Ene Reaction ◽  
Quaternary Centers ◽  
Single Operation ◽  
Target Molecules

The annotinolides are one of the most recent additions to the <i>Lycopodium</i> family of alkaloids, with its members possessing challenging, caged structures that include a [3.2.1]-bicyclic core bearing six contiguous stereocenters, including oxa-, aza-, and all-carbon quaternary centers. Herein, we document a concise and stereoselective route that achieves the first total syntheses of three of its members: annotinolides C, D, and E. Key operations include a gold(I)-catalyzed Conia-ene reaction that fashions much of the main core in a single operation, as well as a number of other challenging and chemoselective transformations to generate the remaining elements. Moreover, efforts utilizing the natural products themselves, seeking adjustments in their oxidation states and the rearrangement of individual ring systems, sheds light on their potential biogenesis with some outcomes counter to those originally proposed. Finally, formal enantioenriched syntheses of the target molecules are also presented.

Sign in / Sign up

Export Citation Format

Share Document