ChemInform Abstract: SYNTHESIS OF A HIGHLY ACTIVE ANGIOTENSIN CONVERTING ENZYME INHIBITOR: 2-(N-((S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANYL)-(1S,3S,5S)-2-AZABICYCLO(3.3.0)OCTANE-3-CARBOXYLIC ACID (HOE 498)

V. TEETZ; R. GEIGER; R. HENNING; H. URBACH

doi:10.1002/chin.198514331

ChemInform Abstract: SYNTHESIS OF A HIGHLY ACTIVE ANGIOTENSIN CONVERTING ENZYME INHIBITOR: 2-(N-((S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANYL)-(1S,3S,5S)-2-AZABICYCLO(3.3.0)OCTANE-3-CARBOXYLIC ACID (HOE 498)

Chemischer Informationsdienst ◽

10.1002/chin.198514331 ◽

1985 ◽

Vol 16 (14) ◽

Author(s):

V. TEETZ ◽

R. GEIGER ◽

R. HENNING ◽

H. URBACH

Keyword(s):

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Highly Active ◽

Hoe 498

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Efficacy, tolerance and hormonal effects of a new oral angiotensin converting enzyme inhibitor, ramipril (HOE 498), in mild to moderate primary hypertension

The American Journal of Cardiology ◽

10.1016/0002-9149(87)90063-4 ◽

1987 ◽

Vol 59 (10) ◽

pp. D104-D109 ◽

Cited By ~ 6

Author(s):

Bengt E. Karlberg ◽

Torbjörn Lindström ◽

Ulf Rosenqvist ◽

K.Peter Öhman

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Primary Hypertension ◽

Converting Enzyme ◽

Hormonal Effects ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man

European Journal of Clinical Pharmacology ◽

10.1007/bf00542412 ◽

1986 ◽

Vol 30 (5) ◽

pp. 541-547 ◽

Cited By ~ 3

Author(s):

R. O. B. Böhm ◽

M. A. van Baak ◽

K. H. Rahn

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Antihypertensive Effect ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Structure of the angiotensin-converting enzyme inhibitor ramiprilat (HOE 498 diacid)

Acta Crystallographica Section C Crystal Structure Communications ◽

10.1107/s0108270187093491 ◽

1987 ◽

Vol 43 (5) ◽

pp. 941-945 ◽

Cited By ~ 5

Author(s):

E. F. Paulus ◽

R. Henning ◽

H. Urbach

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Pharmacokinetics and pharmacodynamics of a novel orally active angiotensin converting enzyme inhibitor (HOE 498) in healthy subjects

European Journal of Clinical Pharmacology ◽

10.1007/bf00556895 ◽

1984 ◽

Vol 27 (5) ◽

pp. 577-581 ◽

Cited By ~ 47

Author(s):

P. U. Witte ◽

R. Irmisch ◽

P. Hajd� ◽

H. Metzger

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Healthy Subjects ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Pharmacokinetics And Pharmacodynamics ◽

Converting Enzyme Inhibitor ◽

Orally Active ◽

Hoe 498

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DISAPPEARANCE OF CAPTOPRIL-INDUCED TASTE DISTURBANCE AFTER SUBSTITUTION WITH ANGIOTENSIN-CONVERTING-ENZYME INHIBITOR HOE 498

The Lancet ◽

10.1016/s0140-6736(85)92115-4 ◽

1985 ◽

Vol 325 (8427) ◽

pp. 517-518 ◽

Cited By ~ 2

Author(s):

H. Mauersberger ◽

P.U. Witte

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Taste Disturbance ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF CARBOXYLIC ACID REPLACEMENT ANALOGS OF THE POTENT ANGIOTENSIN CONVERTING ENZYME INHIBITOR 5(S)-BENZAMIDO-4-OXO-6-PHENYLHEXANOYL-L-PROLINE

Chemischer Informationsdienst ◽

10.1002/chin.198548173 ◽

1985 ◽

Vol 16 (48) ◽

Author(s):

R. G. ALMQUIST ◽

W.-R. CHAO ◽

C. JENNINGS-WHITE

Keyword(s):

Biological Activity ◽

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Antihypertensive effect of Hoe 498, a new angiotensin converting enzyme inhibitor

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)62335-8 ◽

1984 ◽

Vol 36 ◽

pp. 64

Author(s):

Tsutomu Inoue ◽

Katsuyoshi Nagata ◽

Shoryo Hayashi ◽

Takashi Sakaguchi

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Antihypertensive Effect ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Synthesis and biological activity of carboxylic acid replacement analogs of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

Journal of Medicinal Chemistry ◽

10.1021/jm00146a015 ◽

1985 ◽

Vol 28 (8) ◽

pp. 1067-1071 ◽

Cited By ~ 35

Author(s):

Ronald G. Almquist ◽

Wan Ru Chao ◽

Clive Jennings-White

Keyword(s):

Biological Activity ◽

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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A highly potent angiotensin converting enzyme inhibitor: (S,S,S)-5-[N-(1-carboxy-3-phenylpropyl)alanyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-4-carboxylic acid monohydrate, SBG107

Acta Crystallographica Section C Crystal Structure Communications ◽

10.1107/s0108270187095295 ◽

1987 ◽

Vol 43 (3) ◽

pp. 484-488 ◽

Cited By ~ 5

Author(s):

P. Luger ◽

G. Schnorrenberg

Keyword(s):

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Angiotensin-Converting Enzyme Inhibitor-Associated Angioedema

Allergy & Clinical Immunology International - Journal of the World Allergy Organization ◽

10.1027/0838-1925.19.4.164 ◽

2007 ◽

Vol 19 (4) ◽

pp. 164-165

Author(s):

Byol Shin ◽

Richard Lockey

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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