Pharmacokinetics and pharmacodynamics of a novel orally active angiotensin converting enzyme inhibitor (HOE 498) in healthy subjects

P. U. Witte; R. Irmisch; P. Hajd�; H. Metzger

doi:10.1007/bf00556895

Pharmacokinetics and pharmacodynamics of a novel orally active angiotensin converting enzyme inhibitor (HOE 498) in healthy subjects

European Journal of Clinical Pharmacology ◽

10.1007/bf00556895 ◽

1984 ◽

Vol 27 (5) ◽

pp. 577-581 ◽

Cited By ~ 47

Author(s):

P. U. Witte ◽

R. Irmisch ◽

P. Hajd� ◽

H. Metzger

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Healthy Subjects ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Pharmacokinetics And Pharmacodynamics ◽

Converting Enzyme Inhibitor ◽

Orally Active ◽

Hoe 498

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Efficacy, tolerance and hormonal effects of a new oral angiotensin converting enzyme inhibitor, ramipril (HOE 498), in mild to moderate primary hypertension

The American Journal of Cardiology ◽

10.1016/0002-9149(87)90063-4 ◽

1987 ◽

Vol 59 (10) ◽

pp. D104-D109 ◽

Cited By ~ 6

Author(s):

Bengt E. Karlberg ◽

Torbjörn Lindström ◽

Ulf Rosenqvist ◽

K.Peter Öhman

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Primary Hypertension ◽

Converting Enzyme ◽

Hormonal Effects ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Pharmacokinetics, Safety, and Pharmacologic Effects of Fosinopril Sodium, an Angiotensin-Converting Enzyme Inhibitor in Healthy Subjects

The Journal of Clinical Pharmacology ◽

10.1002/j.1552-4604.1991.tb01887.x ◽

1991 ◽

Vol 31 (1) ◽

pp. 58-64 ◽

Cited By ~ 24

Author(s):

Kenneth L. Duchin ◽

Anothy P. Waclawski ◽

Jan I. Tu ◽

James Manning ◽

May Frantz ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Healthy Subjects ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Studies on the antihypertensive effect of single doses of the angiotensin converting enzyme inhibitor ramipril (HOE 498) in man

European Journal of Clinical Pharmacology ◽

10.1007/bf00542412 ◽

1986 ◽

Vol 30 (5) ◽

pp. 541-547 ◽

Cited By ~ 3

Author(s):

R. O. B. Böhm ◽

M. A. van Baak ◽

K. H. Rahn

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Antihypertensive Effect ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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RHC 3659: a new orally active angiotensin converting enzyme inhibitor in normal volunteers.

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.1981.tb01327.x ◽

1981 ◽

Vol 12 (6) ◽

pp. 893-899 ◽

Cited By ~ 19

Author(s):

M Burnier ◽

GA Turini ◽

HR Brunner ◽

M Porchet ◽

D Kruithof ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Normal Volunteers ◽

Converting Enzyme Inhibitor ◽

Orally Active

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Hemodynamic and antihypertensive effects of captopril, an orally active angiotensin converting enzyme inhibitor.

Hypertension ◽

10.1161/01.hyp.1.4.397 ◽

1979 ◽

Vol 1 (4) ◽

pp. 397-401 ◽

Cited By ~ 56

Author(s):

J M Sullivan ◽

B A Ginsburg ◽

T E Ratts ◽

J G Johnson ◽

B R Barton ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Orally Active

Download Full-text

Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2004.02294.x ◽

2004 ◽

Vol 58 (7) ◽

pp. S778-S784

Author(s):

D.B. Brunner ◽

G. Desponds ◽

J. Biollaz ◽

I. Keller ◽

F. Ferber ◽

...

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Healthy Subjects ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Structure of the angiotensin-converting enzyme inhibitor ramiprilat (HOE 498 diacid)

Acta Crystallographica Section C Crystal Structure Communications ◽

10.1107/s0108270187093491 ◽

1987 ◽

Vol 43 (5) ◽

pp. 941-945 ◽

Cited By ~ 5

Author(s):

E. F. Paulus ◽

R. Henning ◽

H. Urbach

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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Pharmacokinetics of SE-9400 (perindopril), a new angiotensin converting enzyme inhibitor, in healthy subjects.

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics ◽

10.3999/jscpt.20.51 ◽

1989 ◽

Vol 20 (1) ◽

pp. 51-52

Author(s):

KEN'ICHI KAHI

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Healthy Subjects ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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ChemInform Abstract: SYNTHESIS OF A HIGHLY ACTIVE ANGIOTENSIN CONVERTING ENZYME INHIBITOR: 2-(N-((S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANYL)-(1S,3S,5S)-2-AZABICYCLO(3.3.0)OCTANE-3-CARBOXYLIC ACID (HOE 498)

Chemischer Informationsdienst ◽

10.1002/chin.198514331 ◽

1985 ◽

Vol 16 (14) ◽

Author(s):

V. TEETZ ◽

R. GEIGER ◽

R. HENNING ◽

H. URBACH

Keyword(s):

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Highly Active ◽

Hoe 498

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DISAPPEARANCE OF CAPTOPRIL-INDUCED TASTE DISTURBANCE AFTER SUBSTITUTION WITH ANGIOTENSIN-CONVERTING-ENZYME INHIBITOR HOE 498

The Lancet ◽

10.1016/s0140-6736(85)92115-4 ◽

1985 ◽

Vol 325 (8427) ◽

pp. 517-518 ◽

Cited By ~ 2

Author(s):

H. Mauersberger ◽

P.U. Witte

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Taste Disturbance ◽

Converting Enzyme Inhibitor ◽

Hoe 498

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