Synthesis and biological activity of carboxylic acid replacement analogs of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

Ronald G. Almquist; Wan Ru Chao; Clive Jennings-White

doi:10.1021/jm00146a015

Synthesis and biological activity of carboxylic acid replacement analogs of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

Journal of Medicinal Chemistry ◽

10.1021/jm00146a015 ◽

1985 ◽

Vol 28 (8) ◽

pp. 1067-1071 ◽

Cited By ~ 35

Author(s):

Ronald G. Almquist ◽

Wan Ru Chao ◽

Clive Jennings-White

Keyword(s):

Biological Activity ◽

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF CARBOXYLIC ACID REPLACEMENT ANALOGS OF THE POTENT ANGIOTENSIN CONVERTING ENZYME INHIBITOR 5(S)-BENZAMIDO-4-OXO-6-PHENYLHEXANOYL-L-PROLINE

Chemischer Informationsdienst ◽

10.1002/chin.198548173 ◽

1985 ◽

Vol 16 (48) ◽

Author(s):

R. G. ALMQUIST ◽

W.-R. CHAO ◽

C. JENNINGS-WHITE

Keyword(s):

Biological Activity ◽

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF PENTAPEPTIDE ANALOGS OF THE POTENT ANGIOTENSIN CONVERTING ENZYME INHIBITOR 5(S)-BENZAMIDO-4-OXO-6-PHENYLHEXANOYL-L-PROLINE

Chemischer Informationsdienst ◽

10.1002/chin.198548172 ◽

1985 ◽

Vol 16 (48) ◽

Author(s):

R. G. ALMQUIST ◽

C. JENNINGS-WHITE ◽

W.-R. CHAO ◽

T. STEEGER ◽

K. WHEELER ◽

...

Keyword(s):

Biological Activity ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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ChemInform Abstract: SYNTHESIS OF A HIGHLY ACTIVE ANGIOTENSIN CONVERTING ENZYME INHIBITOR: 2-(N-((S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANYL)-(1S,3S,5S)-2-AZABICYCLO(3.3.0)OCTANE-3-CARBOXYLIC ACID (HOE 498)

Chemischer Informationsdienst ◽

10.1002/chin.198514331 ◽

1985 ◽

Vol 16 (14) ◽

Author(s):

V. TEETZ ◽

R. GEIGER ◽

R. HENNING ◽

H. URBACH

Keyword(s):

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor ◽

Highly Active ◽

Hoe 498

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Synthesis and biological activity of pentapeptide analogs of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline

Journal of Medicinal Chemistry ◽

10.1021/jm00146a014 ◽

1985 ◽

Vol 28 (8) ◽

pp. 1062-1066 ◽

Cited By ~ 9

Author(s):

Ronald G. Almquist ◽

Clive Jennings-White ◽

Wan Ru Chao ◽

Thomas Steeger ◽

Kevin Wheeler ◽

...

Keyword(s):

Biological Activity ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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A highly potent angiotensin converting enzyme inhibitor: (S,S,S)-5-[N-(1-carboxy-3-phenylpropyl)alanyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-4-carboxylic acid monohydrate, SBG107

Acta Crystallographica Section C Crystal Structure Communications ◽

10.1107/s0108270187095295 ◽

1987 ◽

Vol 43 (3) ◽

pp. 484-488 ◽

Cited By ~ 5

Author(s):

P. Luger ◽

G. Schnorrenberg

Keyword(s):

Carboxylic Acid ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Angiotensin-Converting Enzyme Inhibitor-Associated Angioedema

Allergy & Clinical Immunology International - Journal of the World Allergy Organization ◽

10.1027/0838-1925.19.4.164 ◽

2007 ◽

Vol 19 (4) ◽

pp. 164-165

Author(s):

Byol Shin ◽

Richard Lockey

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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AT1-Receptorblocker Versus Angiotensin Converting Enzyme Inhibitor in Acute Myocardial Infarction? Role of Dosage and Bradykinin on Remodeling, Hemodynamics and Mortality in the Rat Model

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(97)85064-4 ◽

1998 ◽

Vol 31 (2) ◽

pp. 311A

Author(s):

P Gaudron

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Rat Model ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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Faculty Opinions recommendation of Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108262.565200 ◽

2008 ◽

Author(s):

Nikolaus Gravenstein ◽

Felipe Urdaneta

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Angiotensin Receptor Blocker ◽

Enzyme Inhibitor ◽

Diuretic Therapy ◽

Noncardiac Surgery ◽

Converting Enzyme ◽

Angiotensin Receptor ◽

Blocker Therapy ◽

Converting Enzyme Inhibitor

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Faculty Opinions recommendation of Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108262.564286 ◽

2008 ◽

Author(s):

John Augoustides

Keyword(s):

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Angiotensin Receptor Blocker ◽

Enzyme Inhibitor ◽

Diuretic Therapy ◽

Noncardiac Surgery ◽

Converting Enzyme ◽

Angiotensin Receptor ◽

Blocker Therapy ◽

Converting Enzyme Inhibitor

Download Full-text

Faculty Opinions recommendation of Effects on insulin action of adding low-dose thiazide to angiotensin-converting enzyme inhibitor in essential hypertension.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717985483.793473970 ◽

2013 ◽

Author(s):

Bo Carlberg ◽

Mattias Brunström

Keyword(s):

Essential Hypertension ◽

Angiotensin Converting Enzyme ◽

Angiotensin Converting Enzyme Inhibitor ◽

Insulin Action ◽

Low Dose ◽

Enzyme Inhibitor ◽

Converting Enzyme ◽

Converting Enzyme Inhibitor

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