Bone marrow mesenchymal stem cells could acquire the phenotypes of epithelial cells and accelerate vaginal reconstruction combined with small intestinal submucosa

2015 ◽  
Vol 39 (11) ◽  
pp. 1225-1233 ◽  
Author(s):  
Yanan Li ◽  
Fangfang Liu ◽  
Zhiqiang Zhang ◽  
Mingle Zhang ◽  
Shanjin Cao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Epithelial Cells ◽  
Small Intestinal Submucosa ◽  
Vaginal Reconstruction ◽  
Marrow Mesenchymal Stem Cells ◽  
Small Intestinal ◽  
Intestinal Submucosa

scholarly journals Influence of mesenchymal stem cells on stomach tissue engineering using small intestinal submucosa

2013 ◽  
Vol 9 (3) ◽  
pp. 296-304 ◽  
Author(s):  
Hiroki Nakatsu ◽  
Tomio Ueno ◽  
Atsunori Oga ◽  
Mitsuhiro Nakao ◽  
Taku Nishimura ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Small Intestinal Submucosa ◽  
Stomach Tissue ◽  
Small Intestinal ◽  
Intestinal Submucosa

scholarly journals Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells

2021 ◽  
Vol 11 ◽  
Author(s):  
Lei Wu ◽  
Chao Rong ◽  
Qing Zhou ◽  
Xin Zhao ◽  
Xue-Mei Zhuansun ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Epithelial Cells ◽  
Renal Fibrosis ◽  
Kidney Diseases ◽  
Tubular Epithelial Cells ◽  
Renal Tubular Epithelial Cells ◽  
Marrow Mesenchymal Stem Cells ◽  
Renal Tubular

Mesenchymal stem cells (MSCs) have regenerative properties in acute kidney injury (AKI). However, the potential function of MSCs in chronic kidney disease remains elusive. Renal fibrosis is the common endpoint of chronic progressive kidney diseases and causes a considerable health burden worldwide. In this study, the protective effects of bone marrow mesenchymal stem cells (BM-MSCs) were assessed in repeated administration of low-dose cisplatin-induced renal fibrosis mouse model in vivo as well as a TGF-β1-induced fibrotic model in vitro. Differentially expressed miRNAs in mouse renal tubular epithelial cells (mRTECs) regulated by BM-MSCs were screened by high-throughput sequencing. We found microRNA (miR)-146a-5p was the most significant up-regulated miRNA in mRTECs. In addition, the gene Tfdp2 was identified as one target gene of miR-146a-5p by bioinformatics analysis. The expression of Tfdp2 in the treatment of BM-MSCs on cisplatin-induced renal injury was evaluated by immunohistochemistry analysis. Our results indicate that BM-MSC attenuates cisplatin-induced renal fibrosis by regulating the miR-146a-5p/Tfdp2 axis in mRTECs.

477: Bladder Reconstitution with Bone Marrow Derived Stem Cells Seeded on Small Intestinal Submucosa Shows Improved Morphologic and Molecular Composition

2005 ◽  
Vol 173 (4S) ◽  
pp. 131-131
Author(s):  
Steve Y. Chung ◽  
Nikolov Krivorov ◽  
Veronica Rausei ◽  
Lisa Thomas ◽  
Maika Frantzen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Small Intestinal Submucosa ◽  
Molecular Composition ◽  
Small Intestinal ◽  
Intestinal Submucosa
Sign in / Sign up

Export Citation Format

Share Document