Design and Synthesis of Novel N ‐(2‐aminophenyl)benzamide Derivatives as Histone Deacetylase Inhibitors and Their Antitumor Activity Study

2021 ◽  
Author(s):  
Minh Thanh La ◽  
Byung‐Hoon Jeong ◽  
Hee‐Kwon Kim
Keyword(s):  
Antitumor Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Design And Synthesis ◽  
Benzamide Derivatives

scholarly journals Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-PlasmodiumActivity

ChemMedChem ◽  
2017 ◽  
Vol 12 (19) ◽  
pp. 1627-1636 ◽  
Author(s):  
Katharina Stenzel ◽  
Ming Jang Chua ◽  
Sandra Duffy ◽  
Yevgeniya Antonova-Koch ◽  
Stephan Meister ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Terephthalic Acid ◽  
Histone Deacetylase Inhibitors ◽  
Design And Synthesis ◽  
Dual Stage

Design, synthesis and docking studies on benzamide derivatives as histone deacetylase inhibitors

2011 ◽  
Vol 21 (16) ◽  
pp. 4924-4927 ◽  
Author(s):  
Aijun Lu ◽  
Hongpeng Luo ◽  
Minfeng Shi ◽  
Gang Wu ◽  
Yunxia Yuan ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Docking Studies ◽  
Design Synthesis ◽  
Benzamide Derivatives

Design and synthesis of 4-[(s-triazin-2-ylamino)methyl]-N-(2-aminophenyl)-benzamides and their analogues as a novel class of histone deacetylase inhibitors

2008 ◽  
Vol 18 (3) ◽  
pp. 1067-1071 ◽  
Author(s):  
Isabelle Paquin ◽  
Stéphane Raeppel ◽  
Silvana Leit ◽  
Frédéric Gaudette ◽  
Nancy Zhou ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Design And Synthesis

scholarly journals Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

Oncotarget ◽  
2016 ◽  
Vol 7 (15) ◽  
pp. 19559-19574 ◽  
Author(s):  
Chiara Ciardiello ◽  
Maria Serena Roca ◽  
Alessia Noto ◽  
Francesca Bruzzese ◽  
Tania Moccia ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Primary Cultures ◽  
Erbb Receptors ◽  
Synergistic Antitumor Activity

A Novel Series of Potent and Selective Ketone Histone Deacetylase Inhibitors with Antitumor Activity in Vivo

2008 ◽  
Vol 51 (8) ◽  
pp. 2350-2353 ◽  
Author(s):  
Philip Jones ◽  
Sergio Altamura ◽  
Raffaele De Francesco ◽  
Odalys Gonzalez Paz ◽  
Olaf Kinzel ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors

scholarly journals Design and Synthesis of Small Molecules Based on a Substructural Analysis of the Histone Deacetylase Inhibitors TSA and SAHA

2011 ◽  
Vol 8 (3) ◽  
pp. 1394-1400
Author(s):  
Lynda Ekou ◽  
Tchirioua Ekou ◽  
Javier Garcia ◽  
Isabelle Opalinski ◽  
Jean Pierre Gesson
Keyword(s):  
Small Molecules ◽  
Histone Deacetylase ◽  
Histone Deacetylases ◽  
Hydroxamic Acid ◽  
Histone Deacetylase Inhibitors ◽  
Suberoylanilide Hydroxamic Acid ◽  
Considerable Potential ◽  
Design And Synthesis

Inhibitors of histone deacetylases (HDACs) are patent inducers of differentiation and bear considerable potential as drugs for chemoprevention and treatment of cancer. In this paper, we have investigated three synthetic, inhibitors A1a,b, A2a. Analogue hybrid trichostatine A (TSA), suberoylanilide hydroxamic acid SAHA, in order to seek new histone deacetylases (HDACs) inhibitors.

Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent

2005 ◽  
Vol 13 (13) ◽  
pp. 4332-4342 ◽  
Author(s):  
Takayoshi Suzuki ◽  
Azusa Matsuura ◽  
Akiyasu Kouketsu ◽  
Shinya Hisakawa ◽  
Hidehiko Nakagawa ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Design And Synthesis

Design and synthesis of phthalimide-type histone deacetylase inhibitors

2005 ◽  
Vol 15 (20) ◽  
pp. 4427-4431 ◽  
Author(s):  
Chihiro Shinji ◽  
Takanori Nakamura ◽  
Satoko Maeda ◽  
Minoru Yoshida ◽  
Yuichi Hashimoto ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitors ◽  
Design And Synthesis
Sign in / Sign up

Export Citation Format

Share Document