Conducting Cell Scaffold-Poly(3′-aminomethyl-2,2′:5′,2′′-terthiophene)

2015 ◽  
Vol 36 (4) ◽  
pp. 1114-1119 ◽  
Author(s):  
Euh-Duck Jeong ◽  
Jae Young Whang ◽  
Joo-Woon Lee
2019 ◽  
Vol 9 (20) ◽  
pp. 4350 ◽  
Author(s):  
Minh Hieu Ho ◽  
Thien Bui-Thuan Do ◽  
Nhi Ngoc-Thao Dang ◽  
An Nguyen-My Le ◽  
Hanh Thi-Kieu Ta ◽  
...  

Green electrospinning has attracted great interest since non-toxic solvents were shown to be applicable in the fabrication of fibrous materials while ensuring health safety and environmental protection. Less harmful reagents such as acetone (AC) and acetic acid (AA) have been employed in this field in recent years. However, research in this area is still rare, yielding only preliminary results. In this study, two different types of solvents (pure AC and an AA/AC mixture) were used to fabricate electrospun polycaprolactone (PCL) membranes. Sample morphology, wettability, tensile strength, and chemical composition were compared between two types of membranes. Cell–scaffold interaction was also examined by cell adhesion and proliferation assays. The results demonstrate that the two types of solvents had significant effects on membrane morphology, physical strength, and cell adherence behaviors, which should be considered for different application purposes.


Author(s):  
Yu Hirano ◽  
Masaru Kojima ◽  
Mitsuhiro Horade ◽  
Kazuto Kamiyama ◽  
Yasushi Mae ◽  
...  

2007 ◽  
Vol 127 (1-4) ◽  
pp. 330-336 ◽  
Author(s):  
Christos Kokkofitis ◽  
George Karagiannakis ◽  
Michael Stoukides

2012 ◽  
Vol 18 (11) ◽  
pp. 852-858 ◽  
Author(s):  
Pedro F. Costa ◽  
Ana F. Dias ◽  
Rui L. Reis ◽  
Manuela E. Gomes
Keyword(s):  

Author(s):  
Logan Lawrence ◽  
James B. Day ◽  
Pier Paolo Claudio ◽  
Roozbeh (Ross) Salary

Abstract Pneumatic MicroExtrusion (PME) is a direct-write additive manufacturing process, which has emerged as a robust, high-resolution method for the fabrication of a broad spectrum of biological tissues and organs. However, the PME process is intrinsically complex, governed by bio-physio-chemical phenomena as well as material-process interactions. Hence, investigation of the influence of consequential factors on bone scaffold fabrication as well as investigation of cell-scaffold interactions would be an inevitable need. The objective of the work is to investigate the biocompatibility as well as the histological properties of PME-fabricated porous bone scaffolds, composed of polycaprolactone (PCL). To achieve this objective, a media extraction of the scaffold material was tested for cytostatic or cytotoxic activity with the aim to: (i) assess the fabricated scaffolds’ feasibility of use in regenerative medicine, and (ii) determine their structural integrity in a modelled in-vivo environment. In addition, the scaffolds were inoculated with an established osteosarcoma cell line (SAOS-2) and cultured for seven days to investigate the scaffold architecture and cell integration potential. A histological examination was performed on the seeded scaffolds for further in-depth analysis of cell-scaffold interaction. Overall, the results of this study pave the way for future investigation of stem cell incorporation into PME-fabricated PCL scaffolds toward the treatment of osseous fractures and defects.


2009 ◽  
Vol 25 (2) ◽  
pp. 535-542 ◽  
Author(s):  
Yubing Xie ◽  
Yong Yang ◽  
Xihai Kang ◽  
Ruth Li ◽  
Leonithas I. Volakis ◽  
...  

2014 ◽  
Vol 1648 ◽  
Author(s):  
Yuta Kurashina ◽  
Shogo Miyata ◽  
Jun Komotori ◽  
Tadayoshi Koyama

ABSTRACTThree types of 316L stainless steel surface with different topography were prepared by a Fine Particle Peening (FPP) treatment using titania, silica and alumina shot particles and analyzed the cell proliferation and cell-scaffold interaction. FPP-treated surface with titania and silica particles had micro asperities at low frequency. On the other hand, the alumina treated surface had micro asperities at high frequency. L929 fibroblasts were seeded on these specimens and then the number of cells was counted after 72 hours of culturing. The FPP-treated surfaces showed good cell proliferation comparing to polished surface. This indicates that micro asperities formed on the surface encourage cell adhesion. Cell adhesion behavior was evaluated by a scanning electron microscope (SEM) and a fluorescence microscope. Dense filopodia were observed when cells cultured on the FPP-treated surface. This means that FPP treatment enhances cell adhesion and proliferation. The number of cells observed on the FPP-treated surface depended on the shape of asperities formed by FPP treatment; the highest cell counts were obtained on alumina treated surface. This is because cell migration was not inhibited by the shape of alumina treated surface asperities.


1991 ◽  
Vol 232 ◽  
Author(s):  
A. S. Antonov ◽  
A. L. Dyachkov ◽  
A. N. Lagar ◽  
Kov ◽  
L. V. Panina

ABSTRACTBoth frequency and field dependencies of the ac magnetic permeability in composite iron films were measured for different thickness of a conducting cell. Attention has been focused on additional dispersion caused by the skin effect. The data obtained are analyzed on the basis of the effective medium approximation.


2009 ◽  
Vol 19 (18) ◽  
pp. 2789 ◽  
Author(s):  
Lei Li ◽  
Caikang Chen ◽  
Jian Li ◽  
Aijuan Zhang ◽  
Xinyu Liu ◽  
...  

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