scholarly journals Pulsed electromagnetic fields promote repair of focal articular cartilage defects with engineered osteochondral constructs

2020 ◽  
Vol 117 (5) ◽  
pp. 1584-1596 ◽  
Author(s):  
Robert M. Stefani ◽  
Sofia Barbosa ◽  
Andrea R. Tan ◽  
Stefania Setti ◽  
Aaron M. Stoker ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Defects ◽  
Pulsed Electromagnetic Fields ◽  
Pulsed Electromagnetic ◽  
Articular Cartilage Defects

scholarly journals Pulse electromagnetic fields enhance the repair of rabbit articular cartilage defects with magnetic nano-hydrogel

RSC Advances ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 541-550 ◽  
Author(s):  
Jianghong Huang ◽  
Zhaofeng Jia ◽  
Yujie Liang ◽  
Zhiwang Huang ◽  
Zhibin Rong ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Articular Cartilage ◽  
Electromagnetic Fields ◽  
Cartilage Defects ◽  
Pulsed Electromagnetic Fields ◽  
Marrow Mesenchymal Stem Cells ◽  
Pulse Electromagnetic Fields ◽  
Pulsed Electromagnetic ◽  
Articular Cartilage Defects ◽  
Rabbit Articular Cartilage

Pulsed electromagnetic fields combined with magnetic nano-hydrogel can promote bone marrow mesenchymal stem cells to repair rabbit articular cartilage defects.

Effect of pulsed electromagnetic fields on maturation of regenerate bone in a rabbit limb lengthening model

2005 ◽  
Vol 24 (1) ◽  
pp. 2-10 ◽  
Author(s):  
Kenneth F. Taylor ◽  
Nozumu Inoue ◽  
Bahman Rafiee ◽  
John E. Tis ◽  
Kathleen A. McHale ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Limb Lengthening ◽  
Pulsed Electromagnetic Fields ◽  
Pulsed Electromagnetic

Effects of Pulsed Electromagnetic Fields on Rat Eye

1999 ◽  
Vol 18 (2) ◽  
pp. 157-164
Author(s):  
Gianluca Giavaresi ◽  
Francesco Broccoli ◽  
Milena Fini ◽  
Paola Torricelli ◽  
Paola Versura ◽  
...  
Keyword(s):  
Electromagnetic Fields ◽  
Pulsed Electromagnetic Fields ◽  
Pulsed Electromagnetic

scholarly journals A composite scaffold of Wharton’s jelly and chondroitin sulphate loaded with human umbilical cord mesenchymal stem cells repairs articular cartilage defects in rat knee

2021 ◽  
Vol 32 (4) ◽  
Author(s):  
Zhong Li ◽  
Yikang Bi ◽  
Qi Wu ◽  
Chao Chen ◽  
Lu Zhou ◽  
...  
Keyword(s):  
Stem Cells ◽  
Articular Cartilage ◽  
Composite Scaffold ◽  
Biomechanical Properties ◽  
Cartilage Defects ◽  
Human Umbilical Cord ◽  
Composite Scaffolds ◽  
Articular Cartilage Defects

AbstractTo evaluate the performance of a composite scaffold of Wharton’s jelly (WJ) and chondroitin sulfate (CS) and the effect of the composite scaffold loaded with human umbilical cord mesenchymal stem cells (hUCMSCs) in repairing articular cartilage defects, two experiments were carried out. The in vitro experiments involved identification of the hUCMSCs, construction of the biomimetic composite scaffolds by the physical and chemical crosslinking of WJ and CS, and testing of the biomechanical properties of both the composite scaffold and the WJ scaffold. In the in vivo experiments, composite scaffolds loaded with hUCMSCs and WJ scaffolds loaded with hUCMSCs were applied to repair articular cartilage defects in the rat knee. Moreover, their repair effects were evaluated by the unaided eye, histological observations, and the immunogenicity of scaffolds and hUCMSCs. We found that in vitro, the Young’s modulus of the composite scaffold (WJ-CS) was higher than that of the WJ scaffold. In vivo, the composite scaffold loaded with hUCMSCs repaired rat cartilage defects better than did the WJ scaffold loaded with hUCMSCs. Both the scaffold and hUCMSCs showed low immunogenicity. These results demonstrate that the in vitro construction of a human-derived WJ-CS composite scaffold enhances the biomechanical properties of WJ and that the repair of knee cartilage defects in rats is better with the composite scaffold than with the single WJ scaffold if the scaffold is loaded with hUCMSCs.

Sign in / Sign up

Export Citation Format

Share Document