Effects of folic acid fortification on spina bifida prevalence in Brazil

2011 ◽  
Vol 91 (9) ◽  
pp. 831-835 ◽  
Author(s):  
Iêda Maria Orioli ◽  
Ricardo Lima do Nascimento ◽  
Jorge Santiago López-Camelo ◽  
Eduardo Enrique Castilla
Keyword(s):  
Folic Acid ◽  
Spina Bifida ◽  
Folic Acid Fortification

Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States

Teratology ◽  
2002 ◽  
Vol 66 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Laura J. Williams ◽  
Cara T. Mai ◽  
Larry D. Edmonds ◽  
Gary M. Shaw ◽  
Russell S. Kirby ◽  
...  
Keyword(s):  
United States ◽  
Folic Acid ◽  
Spina Bifida ◽  
The United States ◽  
Folic Acid Fortification

Prevalence of Spina Bifida and Anencephaly During the Transition to Mandatory Folic Acid Fortification in the United States

2003 ◽  
Vol 58 (2) ◽  
pp. 90-92
Author(s):  
Laura J. Williams ◽  
Cara T. Mai ◽  
Larry D. Edmonds ◽  
Gary M. Shaw ◽  
Russell S. Kirby ◽  
...  
Keyword(s):  
United States ◽  
Folic Acid ◽  
Spina Bifida ◽  
The United States ◽  
Folic Acid Fortification

scholarly journals Global Birth Prevalence of Spina Bifida by Folic Acid Fortification Status: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 106 (1) ◽  
pp. 159-159 ◽  
Author(s):  
Callie A. M. Atta ◽  
Kirsten M. Fiest ◽  
Alexandra D. Frolkis ◽  
Nathalie Jette ◽  
Tamara Pringsheim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Folic Acid ◽  
Spina Bifida ◽  
Meta Analysis ◽  
Birth Prevalence ◽  
Folic Acid Fortification

scholarly journals Folic Acid Intake and Spina Bifida in the Era of Dietary Folic Acid Fortification

Epidemiology ◽  
2011 ◽  
Vol 22 (5) ◽  
pp. 731-737 ◽  
Author(s):  
Katherine Ahrens ◽  
Mahsa M. Yazdy ◽  
Allen A. Mitchell ◽  
Martha M. Werler
Keyword(s):  
Folic Acid ◽  
Spina Bifida ◽  
Folic Acid Intake ◽  
Folic Acid Fortification ◽  
Acid Intake

Spina bifida before and after folic acid fortification in Canada

2008 ◽  
Vol 82 (9) ◽  
pp. 622-626 ◽  
Author(s):  
Philippe De Wals ◽  
Fassiatou Tairou ◽  
Margot I. Van Allen ◽  
R. Brian Lowry ◽  
Jane A. Evans ◽  
...  
Keyword(s):  
Folic Acid ◽  
Spina Bifida ◽  
Folic Acid Fortification ◽  
Before And After

scholarly journals Global Birth Prevalence of Spina Bifida by Folic Acid Fortification Status: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 106 (1) ◽  
pp. e24-e34 ◽  
Author(s):  
Callie A. M. Atta ◽  
Kirsten M. Fiest ◽  
Alexandra D. Frolkis ◽  
Nathalie Jette ◽  
Tamara Pringsheim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Folic Acid ◽  
Spina Bifida ◽  
Meta Analysis ◽  
Birth Prevalence ◽  
Folic Acid Fortification

scholarly journals Folate status and health: challenges and opportunities

2016 ◽  
Vol 44 (3) ◽  
Author(s):  
Rima Obeid ◽  
Konrad Oexle ◽  
Anke Rißmann ◽  
Klaus Pietrzik ◽  
Berthold Koletzko
Keyword(s):  
Folic Acid ◽  
Spina Bifida ◽  
Child Mortality ◽  
Heart Diseases ◽  
Health Problems ◽  
Reproductive Age ◽  
Mortality And Morbidity ◽  
Folic Acid Fortification ◽  
Dietary Folate ◽  
Folate Status

AbstractEach year approximately 2400 pregnancies develop folic acid-preventable spina bifida and anencephaly in Europe. Currently, 70% of all affected pregnancies are terminated after prenatal diagnosis. The prevalence of neural tube defects (NTDs) has been significantly lowered in more than 70 countries worldwide by applying fortification with folic acid. Periconceptional supplementation of folic acid also reduces the risk of congenital heart diseases, preterm birth, low birth weight, and health problems associated with child mortality and morbidity. All European governments failed to issue folic acid fortification of centrally processed and widely eaten foods in order to prevent NTDs and other unwanted birth outcomes. The estimated average dietary intake of folate in Germany is 200 μg dietary folate equivalents (DFE)/day. More than half of German women of reproductive age do not consume sufficient dietary folate to achieve optimal serum or red blood cell folate concentrations (>18 or 1000 nmol/L, respectively) necessary to prevent spina bifida and anencephaly. To date, targeted supplementation is recommended in Europe, but this approach failed to reduce the rate of NTDs during the last 10 years. Public health centers for prenatal care and fortification with folic acid in Europe are urgently needed. Only such an action will sufficiently improve folate status, prevent at least 50% of the NTD cases, reduce child mortality and morbidity, and alleviate other health problems associated with low folate such as anemia.

A Public Health Success Story: Folic Acid Fortification and Supplementation for Prevention of Neural Tube Defects

2004 ◽  
Author(s):  
Linda Longerich ◽  
Roy West ◽  
Ed Randell ◽  
Marian Crowley ◽  
Shiliang Liu ◽  
...  
Keyword(s):  
Public Health ◽  
Folic Acid ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Success Story ◽  
Folic Acid Fortification
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