scholarly journals Restored Immunosuppressive Effect of Mesenchymal Stem Cells on B Cells After Olfactory 1/Early B Cell Factor-Associated Zinc-Finger Protein Down-Regulation in Patients With Systemic Lupus Erythematosus

2014 ◽  
Vol 66 (12) ◽  
pp. 3413-3423 ◽  
Author(s):  
Xuebing Feng ◽  
Nan Che ◽  
Yan Liu ◽  
Haifeng Chen ◽  
Dandan Wang ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
B Cell ◽  
Zinc Finger ◽  
Lupus Erythematosus ◽  
Zinc Finger Protein ◽  
Systemic Lupus ◽  
Finger Protein ◽  
Early B Cell Factor

Stem cell transplantation: progress in Asia

Lupus ◽  
2010 ◽  
Vol 19 (12) ◽  
pp. 1468-1473 ◽  
Author(s):  
L. Sun
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Hematopoietic Stem ◽  
The Past ◽  
Complex Autoimmune Disease ◽  
Significant Mortality

Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multiorgan involvement and high mortality, which was reduced because of the most widely and classically used immunosuppressive therapies. However, some patients continue to have significant mortality. So a shift in the approach to the treatment of SLE is needed. In the past decade, most transplants have been performed in the treatment of SLE with allogeneic or autologous hematopoietic stem cells and currently emerging mesenchymal stem cells. There are some important differences between the two procedures.

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus

Lupus ◽  
2010 ◽  
Vol 19 (7) ◽  
pp. 850-859 ◽  
Author(s):  
Y. Nie ◽  
C. Lau ◽  
A. Lie ◽  
G. Chan ◽  
M. Mok
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Lupus Erythematosus ◽  
Systemic Lupus
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