Improvement of the short- and long-term mechanical properties of injection-molded poly(etheretherketone) and hydroxyapatite nanocomposites

2016 ◽  
Vol 134 (7) ◽  
Author(s):  
Andre Luis Marcomini ◽  
Bruna Turino Rego ◽  
Rosario Elida Suman Bretas
2006 ◽  
Vol 291 (5) ◽  
pp. H2354-H2361 ◽  
Author(s):  
X. Guo ◽  
M. J. Oldham ◽  
M. T. Kleinman ◽  
R. F. Phalen ◽  
G. S. Kassab

Cigarette smoking (CS) is a major risk factor for vascular disease. The aim of this study was to quantitatively assess the influence of CS on mouse arteries. We studied the effect of short-term (6 wk) and long-term (16 wk) CS exposure on structural and mechanical properties of coronary arteries compared with that of control mice. We also examined the reversibility of the deleterious effects of CS on structural [e.g., wall thickness (WT)], mechanical (e.g., stiffness), and biochemical [e.g., nitric oxide (NO) by-products] properties with the cessation of CS. The left and right coronary arteries were cannulated in situ and mechanically distended. The stress, strain, elastic modulus, and WT of coronary arteries were determined. Western blot analysis was used to analyze endothelial NO synthase (eNOS) in the femoral and carotid arteries of the same mice, and NO by-products were determined by measuring the levels of nitrite. Our results show that the mean arterial pressure was increased by CS. Furthermore, CS significantly increased the elastic modulus, decreased stress and strain, and increased the WT and WT-to-radius ratio compared with those of control mice. The reduction of eNOS protein expression was found only after long-term CS exposure. Moreover, the NO metabolite was markedly decreased in CS mice after short- and long-term exposure of CS. These findings suggest that 16 wk of CS exposure can cause an irreversible deterioration of structural and elastic properties of mouse coronary arteries. The decrease in endothelium-derived NO in CS mice was seen to significantly correlate with the remodeling of arterial wall.


Author(s):  
A. Rezaei ◽  
M. Salimi Jazi ◽  
G. Karami ◽  
M. Ziejewski

Traumatic brain injury (TBI) is one of the most important problems in biomechanical engineering, and there have been many experiments conducted in order to characterize the mechanical properties of brain tissue. However, obtaining fresh human brain tissue is difficult, if not impossible. Also, the sample preparation and testing protocols must be carried out with great delicacy because brain tissue is very soft and vulnerable to being deformed under a very small amount of load. Most importantly, according to several researchers, each sample must be tested only one time as the tissue may be damaged and its characteristics subsequently changed. This paper is intended to examine the amount of decay that can happen in material characteristics due to retesting. A stress relaxation test is conducted on the same samples of the swine brain tissue multiple times in small and large deformations. The mechanical properties of the substance are calculated before and after retesting, and the constants of the tissue, as mechanical characteristics, are determined and compared. Short- and long-term moduli, relaxation times and relaxation functions are calculated and compared to understand how much they decay after repeating the experiments. The results show that retesting does not significantly change the elastic part of the tissue characteristics, but the viscous behavior shows a relatively sizeable change. The ability to account for the material decay of the samples due to repetition of the experiments results in the need for fewer samples and less preparation time and effort.


2008 ◽  
Vol 199 (3) ◽  
pp. 379-388 ◽  
Author(s):  
Rhonda D Prisby ◽  
Joshua M Swift ◽  
Susan A Bloomfield ◽  
Harry A Hogan ◽  
Michael D Delp

Osteopenia and an enhanced risk of fracture often accompany type 1 diabetes. However, the association between type 2 diabetes and bone mass has been ambiguous with reports of enhanced, reduced, or similar bone mineral densities (BMDs) when compared with healthy individuals. Recently, studies have also associated type 2 diabetes with increased fracture risk even in the presence of higher BMDs. To determine the temporal relationship between type 2 diabetes and bone remodeling structural and mechanical properties at various bone sites were analyzed during pre-diabetes (7 weeks), short-term (13 weeks), and long-term (20 weeks) type 2 diabetes. BMDs and bone strength were measured in the femora and tibiae of Zucker diabetic fatty rats, a model of human type 2 diabetes. Increased BMDs (9–10%) were observed in the distal femora, proximal tibiae, and tibial mid- shafts in the pre-diabetic condition that corresponded with higher plasma insulin levels. During short- and long-term type 2 diabetes, various parameters of bone strength and BMDs were lower (9–26%) in the femoral neck, distal femora, proximal tibiae, and femoral and tibial mid-shafts. Correspondingly, blood glucose levels increased by 125% and 153% during short- and long-term diabetes respectively. These data indicate that alterations in BMDs and bone mechanical properties are closely associated with the onset of hyperinsulinemia and hyperglycemia, which may have direct adverse effects on skeletal tissue. Consequently, disparities in the human literature regarding the effects of type 2 diabetes on skeletal properties may be associated with the bone sites studied and the severity or duration of the disease in the patient population studied.


1996 ◽  
Vol 74 (6) ◽  
pp. 859-869 ◽  
Author(s):  
C. H. Pang ◽  
M. G. Scanlon

The mechanical properties of plant materials and plant structures influence the form, function, distribution, and utilization of plants. The shear and compressive stiffnesses of different regions of potato parenchyma were measured to more fully characterize the mechanical properties of this important storage organ. Measurements were performed on tubers that had been stored for 1 and 10 months. Slices and cylinders of parenchyma were excised from the centre of the tubers in three directions (and slices from the outer portion in two directions). Slices were subjected to small-strain oscillatory shear at frequencies of 0.02, 0.2, and 2 Hz. Cylinders were subjected to three cycles of uniaxial compression at 2 and 20 cm∙min−1. The coefficient of variation of measured parameters ranged on average from 16 to 44% for both crops and both tests. At small strains, potato parenchyma behaved essentially as an elastic material. The results from both small-strain oscillatory shear and uniaxial compression suggested that potato parenchyma is anisotropic in nature. Slices from the outer and inner regions of the tuber had different shear stiffness values. The shear stiffness of tubers stored for 1 month was approximately 70% greater than those stored for 10 months. Repeated compressive loading of potato parenchyma cylinders ameliorated the differences in stiffness and energy absorption between short- and long-term stored tubers, attributable to movement of fluids from the cells during compression. The observations emphasize the complexity of potato tissue and how its mechanical properties change during storage. Keywords: shear, compression, energy absorption, stiffness, turgor, storage, anisotropicity.


2014 ◽  
Vol 51 ◽  
pp. 414-423 ◽  
Author(s):  
Lily D. Poulikakos ◽  
Salomé dos Santos ◽  
Moises Bueno ◽  
Simon Kuentzel ◽  
Martin Hugener ◽  
...  

Author(s):  
Asghar Rezaei ◽  
Ghodrat Karami ◽  
Fardad Azarmi ◽  
Mehdi Salimi Jazi ◽  
Mariusz Ziejewski

This research is intended to examine the amount of changes that can happen in material characteristics after retesting. Stress relaxation test is conducted on the same samples of the swine brain tissue for several times in small and large deformations. The mechanical properties of the substance are calculated before and after retest and the constants of the tissue, as mechanical characteristics, are determined and compared. Short- and long-term moduli, relaxation times and relaxation functions are of those data that are calculated and compared to understand how much they decay after repeating the experiments. The results show that applying different tests on one sample slightly changes the mechanical properties of the tissue and, as a result, it is partly possible to perform more than one test on the same sample resulting in less sample preparation, time and effort.


2021 ◽  
Author(s):  
Anil Mathew ◽  
Silpa Abraham ◽  
Shamilin Stephen ◽  
Anna Serene Babu ◽  
Siddaramana Gowd ◽  
...  

Current clinical demand in dental implantology is for a multifunctional device with optimum mechanical properties, improved biocompatibility, and bioactivity, and having differential interactions with cells and pathogenic agents. This would...


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