Acrylic bone cements: Effects of the poly(methyl methacrylate) powder size and chitosan addition on their properties

2013 ◽  
Vol 131 (3) ◽  
pp. n/a-n/a ◽  
Author(s):  
Tugba Endogan ◽  
Aysel Kiziltay ◽  
Gamze Torun Kose ◽  
Nil Comunoglu ◽  
Tahsin Beyzadeoglu ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Bone Cements ◽  
Powder Size ◽  
Poly Methyl Methacrylate

Improved bone ingrowth of tricalcium phosphate filled Poly(methyl methacrylate) (PMMA) bone cements in vivo

2019 ◽  
Vol 76 ◽  
pp. 513-521 ◽  
Author(s):  
Shan Gao ◽  
Yang Lv ◽  
Liang Yuan ◽  
Huihui Ren ◽  
Teng Wu ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Tricalcium Phosphate ◽  
Bone Ingrowth ◽  
Bone Cements ◽  
Poly Methyl Methacrylate

Poly(methyl methacrylate)-Based Composite Bone Cements With Different Types of Reinforcement Agents

2021 ◽  
Author(s):  
Sanaz Soleymani Eil Bakhtiari ◽  
Hamid Reza Bakhsheshi-Rad ◽  
Saeed Karbasi ◽  
Ahmad Fauzi Ismail ◽  
Safian Sharif ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Bone Cements ◽  
Poly Methyl Methacrylate ◽  
Different Types ◽  
Composite Bone

scholarly journals Treatment of Hydatid Disease of the Tibia by Using Poly-Methyl Methacrylate (PMMA) Bone Cements, Clinical Results of a Case Series

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Mohammad Gharehdaghi ◽  
Mohammad Hossein Ebrahimzadeh ◽  
Nahid Mojaver ◽  
Hami Ashraf ◽  
Hassan Rahimi Shoorin ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Hydatid Disease ◽  
Case Series ◽  
Clinical Results ◽  
Bone Cements ◽  
Poly Methyl Methacrylate

scholarly journals Antibacterial effect of acrylic bone cements loaded with drugs of different action’s mechanism

2019 ◽  
Vol 13 (06) ◽  
pp. 487-495
Author(s):  
Lizette Morejón Alonso ◽  
Iran Fernández Torres ◽  
Ángela M Zayas Tamayo ◽  
Oscar Ernesto Ledea Lozano ◽  
Ivette Durán Ramos ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Methyl Methacrylate ◽  
Antibacterial Effect ◽  
Inhibitory Effect ◽  
Bone Cements ◽  
Trial Period ◽  
Poly Methyl Methacrylate ◽  
Microdilution Method ◽  
Vis Spectroscopy

Introduction: Antibiotic-loaded bone cements of poly(methyl methacrylate) are considered as very useful biomaterials for the management of corporal deep osseous infections. However, the high prevalence of resistant germs and polymicrobial infections makes it necessary to search for new formulations of bone cements containing antibiotics for local antibacterial therapy. In this work, bone cements loaded with drugs with different mechanism of action were evaluated to determine its antibacterial effectiveness on Pseudomonas aeruginosa. Methodology: Poly(methyl methacrylate) cements loaded with 10 wt.% of Oleozon®, mixtures of Ciprofloxacin/Meropenem and Ciprofloxacin/Meropenem/Oleozon® were prepared. The in vitro drugs release in water was followed by UV-Vis spectroscopy, and their antibacterial activity against Pseudomonas aeruginosa was evaluated for 11 days using the microdilution method. Results: All the extracts demonstrated an inhibitory effect on the growth of the strain during the whole trial period. Extracts from cement with Oleozon® only presented a total antibacterial inhibitory effect during 20 hours for the extracts taken at day 1 while the extracts from the cements loaded with mixtures of Ciprofloxacin/Meropenem and Ciprofloxacin/Meropenem/Oleozon® showed complete inhibition of the growth of the microorganism, even at 11 days. At the end of the trial period, some of the drugs remained inside the matrices, indicating that they can be released for a longer time in treatments. Conclusions: The results indicated a positive antibacterial effect by the combined used of the two or the three drugs tested against the Gram-negative bacilli Pseudomonas aeruginosa, so these proposal may be a valid alternative to be considered by surgeons.

Physical and Mechanical Characterization of Poly(methyl methacrylate) Based Cements for Bone Regeneration

2021 ◽  
Vol 13 (3) ◽  
pp. 427-435
Author(s):  
Abeer Sheikh ◽  
Eraj Humayun Mirza ◽  
Saif ur Rehman Baig ◽  
Fatima Fareedi ◽  
Umar Khan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Methyl Methacrylate ◽  
Chemical Characterization ◽  
Acrylic Resin ◽  
Physicochemical Characteristics ◽  
Contact Angle Measurement ◽  
Angle Measurement ◽  
Bone Cements ◽  
Poly Methyl Methacrylate ◽  
Measurement Surface

This laboratory study set out to characterize Calcium Phosphate (CaP) based bone cements with added Zinc Oxide (ZnO) embedded in Poly (methyl methacrylate) (PMMA). Bone cements with varying percentages of CaP mixed with and without varying percentages of ZnO in PMMA were fabricated by one-step polymerization by reacting equimolar ratios of MMA powder and acrylic resin. Neat-PMMA was used as control throughout the experiment. Fabricated samples were tested for their contact angle measurement, surface roughness, nanohardness, elastic modulus, and also their chemical characterization using Fourier-transform infrared spectroscopy (FTIR) and Raman spectroscopy. A one-way analysis of variance (ANOVA) was used as a statistical method, and a p-value of less than 0.05 was considered statistically significant. It was found that increasing CaP content elevated the hydrophobicity of the composites while mechanical properties increased with the increase of CaP. On the contrary, the addition of ZnO did not show any significant effect. The optimal concentration was observed to be at 20% CaP loading where the mechanical properties were balanced with the hydrophilic nature of CaP. It was also noted that different wt.% of ZnO and CaP did not affect the physicochemical characteristics of the composites. The PMMA-CaP composites demonstrated encouraging results and necessitate further studies to ascertain the implementation of these bone cements clinically.

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