Core‐shell structured magnetite silica‐supported hexatungstate: A novel and powerful nanocatalyst for the synthesis of biologically active pyrazole derivatives

2021 ◽  
Author(s):  
Ramin Nemati ◽  
Dawood Elhamifar ◽  
Ali Zarnegaryan ◽  
Masoumeh Shaker
Keyword(s):  
Biologically Active ◽  
Core Shell ◽  
Pyrazole Derivatives

Arylpyrazoles: Heterocyclic Scaffold of Immense Therapeutic Application

2020 ◽  
Vol 24 (14) ◽  
pp. 1555-1581
Author(s):  
Garima Tripathi ◽  
Anil Kumar Singh ◽  
Abhijeet Kumar
Keyword(s):  
Biological Activities ◽  
Biologically Active ◽  
Present Review ◽  
Pyrazole Derivatives ◽  
Therapeutic Application ◽  
Diverse Range ◽  
Major Class ◽  
Anti Inflammatory

Among the major class of heterocycles, the N-heterocycles, such as pyrazoles, are scaffolds of vast medicinal values. Various drugs and other biologically active molecules are known to contain these N-heterocycles as core motifs. Specifically, arylpyrazoles have exhibited a diverse range of biological activities, including anti-inflammatory, anticancerous, antimicrobial and various others. For instance, arylpyrazoles are present as core moieties in various insecticides, fungicides and drugs such as Celebrex and Trocoxil. The present review will be highlighting the significant therapeutic importance of pyrazole derivatives developed in the last few years.

Core–shell structured magnetic silica supported propylamine/molybdate complexes: an efficient and magnetically recoverable nanocatalyst

2019 ◽  
Vol 43 (31) ◽  
pp. 12283-12291 ◽  
Author(s):  
Maryam Neysi ◽  
Ali Zarnegaryan ◽  
Dawood Elhamifar
Keyword(s):  
Core Shell ◽  
Pyrazole Derivatives ◽  
Magnetic Silica

A novel core–shell structured magnetic silica supported propylamine/molybdate complex (Fe3O4@SiO2/Pr-NMo[Mo5O18]) is prepared, characterized and applied as an effective and easily recoverable nanocatalyst in the synthesis of pyrano-pyrazole derivatives.

Core-shell based nanocarriers as delivery systems for biologically active metal ions and drugs

2008 ◽  
Vol 132 (3) ◽  
pp. e32-e33 ◽  
Author(s):  
M.A. Quadir ◽  
C. Treiber ◽  
G. Multhaup ◽  
M. Körner ◽  
R. Haag
Keyword(s):  
Metal Ions ◽  
Delivery Systems ◽  
Biologically Active ◽  
Core Shell ◽  
Active Metal

scholarly journals Pyrazolyl-Ureas as Interesting Scaffold in Medicinal Chemistry

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3457 ◽  
Author(s):  
Chiara Brullo ◽  
Federica Rapetti ◽  
Olga Bruno
Keyword(s):  
P38 Mapk ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Biological Data ◽  
Biologically Active ◽  
Pyrazole Derivatives ◽  
Intracellular Level ◽  
Active Compounds ◽  
Privileged Scaffold

The pyrazole nucleus has long been known as a privileged scaffold in the synthesis of biologically active compounds. Within the numerous pyrazole derivatives developed as potential drugs, this review is focused on molecules characterized by a urea function directly linked to the pyrazole nucleus in a different position. In the last 20 years, the interest of numerous researchers has been especially attracted by pyrazolyl-ureas showing a wide spectrum of biological activities, ranging from the antipathogenic activities (bacteria, plasmodium, toxoplasma, and others) to the anticarcinogenic activities. In particular, in the anticancer field, pyrazolyl-ureas have been shown to interact at the intracellular level on many pathways, in particular on different kinases such as Src, p38-MAPK, TrKa, and others. In addition, some of them evidenced an antiangiogenic potential that deserves to be explored. This review therefore summarizes all these biological data (from 2000 to date), including patented compounds.

Review: biologically active pyrazole derivatives

2017 ◽  
Vol 41 (1) ◽  
pp. 16-41 ◽  
Author(s):  
Anam Ansari ◽  
Abad Ali ◽  
Mohd Asif ◽  
Shamsuzzaman Shamsuzzaman
Keyword(s):  
Heterocyclic Compounds ◽  
Therapeutic Agents ◽  
Biologically Active ◽  
Pyrazole Derivatives

Nitrogen-containing heterocyclic compounds and their derivatives have historically been invaluable as a source of therapeutic agents.

scholarly journals Green fabrication of biologically active magnetic core-shell Fe3O4/Au nanoparticles and their potential anticancer effect

2019 ◽  
Vol 96 ◽  
pp. 51-57 ◽  
Author(s):  
Zahra Izadiyan ◽  
Kamyar Shameli ◽  
Mikio Miyake ◽  
Sin-Yeang Teow ◽  
Suat-Cheng Peh ◽  
...  
Keyword(s):  
Au Nanoparticles ◽  
Magnetic Core ◽  
Biologically Active ◽  
Core Shell ◽  
Anticancer Effect

Chromatographic behavior of the biologically active proline derivative captopril on particulate, monolithic and core–shell narrow bore columns

2012 ◽  
Vol 4 (12) ◽  
pp. 4373
Author(s):  
Constantinos K. Zacharis ◽  
Theano D. Karakosta ◽  
Paraskevas D. Tzanavaras ◽  
Pantelis G. Rigas ◽  
Demetrius G. Themelis
Keyword(s):  
Biologically Active ◽  
Chromatographic Behavior ◽  
Core Shell ◽  
Narrow Bore Columns
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