Total Synthesis and Biological Investigation of (−)‐Artemisinin: The Antimalarial Activity of Artemisinin Is not Stereospecific

2018 ◽  
Vol 57 (27) ◽  
pp. 8293-8296 ◽  
Author(s):  
Johannes Krieger ◽  
Toni Smeilus ◽  
Marcel Kaiser ◽  
Ean‐Jeong Seo ◽  
Thomas Efferth ◽  
...  
2019 ◽  
Vol 55 (52) ◽  
pp. 7434-7437 ◽  
Author(s):  
Christopher Bérubé ◽  
Dominic Gagnon ◽  
Alexandre Borgia ◽  
Dave Richard ◽  
Normand Voyer

This work describes the first total synthesis of mortiamides and their anti-malarial activity against a multi-drug resistant strain of Plasmodium falciparum.


2015 ◽  
Vol 137 (23) ◽  
pp. 7314-7317 ◽  
Author(s):  
Andrew D. Steele ◽  
Kyle W. Knouse ◽  
Colleen E. Keohane ◽  
William M. Wuest

2011 ◽  
Vol 17 (48) ◽  
pp. 13544-13552 ◽  
Author(s):  
Trent Conroy ◽  
Jin T. Guo ◽  
Roger G. Linington ◽  
Nicholas H. Hunt ◽  
Richard J. Payne

ChemInform ◽  
2015 ◽  
Vol 46 (48) ◽  
pp. no-no
Author(s):  
Andrew D. Steele ◽  
Kyle W. Knouse ◽  
Colleen E. Keohane ◽  
William M. Wuest

2010 ◽  
Vol 12 (23) ◽  
pp. 5576-5579 ◽  
Author(s):  
Trent Conroy ◽  
Jin T. Guo ◽  
Nicholas H. Hunt ◽  
Richard J. Payne

RSC Advances ◽  
2017 ◽  
Vol 7 (16) ◽  
pp. 9813-9818 ◽  
Author(s):  
Zhibin Zhang ◽  
Xiao Leng ◽  
Shenkun Yang ◽  
Cheng Liang ◽  
Shuangping Huang ◽  
...  

Aculeatin A, isolated from the plant Amomum aculeatum, is a dispirocyclic compound having antimalarial activity. We describe a novel synthetic approach to aculeatin A via a stepwise strategy.


2020 ◽  
Vol 83 (6) ◽  
pp. 1778-1783
Author(s):  
Christopher Bérubé ◽  
Alexandre Borgia ◽  
Dominic Gagnon ◽  
Angana Mukherjee ◽  
Dave Richard ◽  
...  

2020 ◽  
Vol 142 (36) ◽  
pp. 15476-15487
Author(s):  
K. C. Nicolaou ◽  
Johannes Krieger ◽  
Ganesh M. Murhade ◽  
Parthasarathi Subramanian ◽  
Balu D. Dherange ◽  
...  

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