scholarly journals Association of resting heart rate with cognitive decline and dementia in older adults: A prospective population‐based study

2021 ◽  
Vol 17 (S10) ◽  
Author(s):  
Yume Imahori ◽  
Davide Liborio Vetrano ◽  
Xin Xia ◽  
Giulia Grande ◽  
Petter Ljungman ◽  
...  
Keyword(s):  
Older Adults ◽  
Heart Rate ◽  
Cognitive Decline ◽  
Population Based ◽  
Resting Heart Rate ◽  
Population Based Study

scholarly journals Association of resting heart rate with cognitive decline and dementia in older adults: A population‐based cohort study

2021 ◽  
Author(s):  
Yume Imahori ◽  
Davide L. Vetrano ◽  
Xin Xia ◽  
Giulia Grande ◽  
Petter Ljungman ◽  
...  
Keyword(s):  
Older Adults ◽  
Heart Rate ◽  
Cohort Study ◽  
Cognitive Decline ◽  
Population Based ◽  
Resting Heart Rate

scholarly journals Correlation of resting heart rate with anthropometric factors and serum biomarkers in a population-based study: Fasa PERSIAN cohort study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yashar Goorakani ◽  
Massih Sedigh Rahimabadi ◽  
Azizallah Dehghan ◽  
Maryam Kazemi ◽  
Mahsa Rostami Chijan ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cohort Study ◽  
Population Based ◽  
Serum Biomarkers ◽  
Resting Heart Rate ◽  
Population Based Study

scholarly journals Impact of the Apolipoprotein E4 allele on the Relationship Between Healthy Lifestyle and Cognitive Decline: A Population-based Study

2021 ◽  
Author(s):  
Klodian Dhana ◽  
Neelum T Aggarwal ◽  
Kumar B Rajan ◽  
Lisa L Barnes ◽  
Denis A Evans ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Genetic Predisposition ◽  
Healthy Lifestyle ◽  
Population Based ◽  
Cognitive Assessments ◽  
Population Based Study ◽  
Quality Diet ◽  
E4 Allele ◽  
The Impact

Abstract Adherence to a healthy lifestyle –characterized by abstaining from smoking, being physically and cognitively active, having a high-quality diet, and limiting alcohol use– is associated with slower cognitive decline in older adults, but whether this relationship extends to individuals with a genetic predisposition (e.g., ApoE4 carriers) remains uncertain. From the population-based study, the Chicago Health and Aging Project, we followed 3,886 individuals with regular clinical and cognitive assessments from 1993 to 2012. Of 3,886 older adults, 1,269 (32.7%) were ApoE4 carriers. Compared to non-carries, ApoE4 carriers had a faster cognitive decline by -0.027 (95%CI -0.032, -0.023) units per year. In contrast, individuals with 2-3 and 4-5 healthy lifestyle factors had a slower cognitive decline by 0.008 (95%CI 0.002, 0.014) and 0.019 (95%CI 0.011, 0.026) units per year, compared to those with 0-1 factor. In analyses stratified by ApoE4 status, adherence to a healthy lifestyle (e.g., 4-5 vs. 0-1 factors) was associated with a slower rate of cognitive decline in both ApoE4 carriers ($\beta$=0.029 units/year; 95%CI 0.013, 0.045) and non-carriers ($\beta$=0.013, 95%CI 0.005, 0.022). These results underscore the impact of a healthy lifestyle on cognition, particularly among individuals with a genetic predisposition who are more vulnerable to cognitive decline as they age.

Head injuries and cognitive decline among older adults: A population-based study

Neurology ◽  
1999 ◽  
Vol 52 (3) ◽  
pp. 557-557 ◽  
Author(s):  
H. Luukinen ◽  
P. Viramo ◽  
K. Koski ◽  
P. Laippala ◽  
S.-L. Kivela
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Head Injuries ◽  
Population Based ◽  
Population Based Study
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