scholarly journals Increased resting heart rate with pollutants in a population based study

2005 ◽  
Vol 59 (8) ◽  
pp. 685-693 ◽  
Author(s):  
J.-B. Ruidavets
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yashar Goorakani ◽  
Massih Sedigh Rahimabadi ◽  
Azizallah Dehghan ◽  
Maryam Kazemi ◽  
Mahsa Rostami Chijan ◽  
...  

2021 ◽  
Vol 17 (S10) ◽  
Author(s):  
Yume Imahori ◽  
Davide Liborio Vetrano ◽  
Xin Xia ◽  
Giulia Grande ◽  
Petter Ljungman ◽  
...  

2017 ◽  
Vol 119 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Behnam Tajik ◽  
Sudhir Kurl ◽  
Tomi-Pekka Tuomainen ◽  
Kai Savonen ◽  
Jyrki K. Virtanen

AbstractLong-chain n-3 PUFA from fish have been associated with lower risk of CVD. Fish may also contain methylmercury, which may attenuate the inverse associations of the long-chain n-3 PUFA. However, the mechanisms underlying these associations are not fully known. We evaluated the associations of the serum long-chain n-3 PUFA (EPA, DPA and DHA) and hair Hg with resting heart rate (HR), peak HR during cycle ergometer exercise and HR recovery after exercise. A total of 1008 men from the population-based Kuopio Ischaemic Heart Disease Risk Factor Study, aged 42–60 years and free of CVD, were studied. After multivariate-adjustments in ANCOVA, higher serum total long-chain n-3 PUFA concentration was associated with lower resting HR (extreme-quartile difference 2·2 beats/min; 95 % CI 0·2, 4·1, Ptrend across quartiles=0·02), but not with peak HR or HR recovery. Associations were generally similar when EPA, DPA and DHA were evaluated individually, except for DPA, which was also associated with better HR recovery after exercise (extreme-quartile difference 2·1 beats/min; 95 % CI 0·1, 4·2, Ptrend=0·06). Higher hair Hg content had a trend towards lower peak HR after adjusting for the long-chain n-3 PUFA (Ptrend=0·05), but it only slightly attenuated the associations of the serum long-chain n-3 PUFA with HR. These findings suggest that higher serum long-chain n-3 PUFA concentrations are associated with lower resting HR in middle-aged men from Eastern Finland, which may partially explain the potential cardioprotective effect of fish intake.


Diabetes ◽  
2002 ◽  
Vol 51 (3) ◽  
pp. 803-807 ◽  
Author(s):  
C. Panzer ◽  
M. S. Lauer ◽  
A. Brieke ◽  
E. Blackstone ◽  
B. Hoogwerf

Circulation ◽  
2001 ◽  
Vol 103 (suppl_1) ◽  
pp. 1348-1348
Author(s):  
Russell P Tracy ◽  
Anne B Newman ◽  
Jeff D Williamson ◽  
Tamara B Harris ◽  
Steve R Cummings

0022 Inflammatory cytokines enhance the spontaneous beating rate of cardiac myocytes. We hypothesize that higher levels of interleukin-6 (IL-6) may be associated with a higher resting heart rate in a population-based sample. IL-6 (mean±SEM 2.39±0.5 ng/ml, range 0.21-15.96 ng/ml, n=2824) was measured in Health ABC, a cohort study of 3075 well functioning older adults living in Memphis, TN, and Pittsburgh, PA (age 73.6±0.3 years, 51.5% women, 41.7% African American). Heart rate was calculated from electrocardiogram strips recorded at the baseline clinic visit after 15 min resting in supine position. Participants with arrhythmias or conduction anomalies were excluded. After adjustment for demographics, body-mass index, smoking, history of cardiovascular disease, and use of digoxin, beta-blockers, calcium antagonists, anti-inflammatory drugs and antiarrhythmic drugs, higher log (IL-6) was significantly correlated with a higher heart rate (β=.17, p<0.001, n=2377). Such an association was significant in all race and gender strata (white men β=0.17, p<0.001; white women β=0.13, p=0.001; black men β=0.18, p<0.001; black women β=0.18, p<0.001). The overall il-6/heart rate association was even more evident when the analyses were restricted to the participants who had no history of cardiovascular disease and were not using any these cardiovascular drugs (β=0.21, p<0.001, n=1196). The table shows heart rate according to IL-6 quintiles. Circulating IL-6 was strongly and independently correlated with resting heart rate. Circulating IL-6 is a possible biological mediator that may contribute to explain the increased mortality associated with high heart rate. Table 1.


2018 ◽  
Vol 48 (13) ◽  
pp. 2194-2201 ◽  
Author(s):  
Gemma Hammerton ◽  
Jon Heron ◽  
Liam Mahedy ◽  
Barbara Maughan ◽  
Matthew Hickman ◽  
...  

AbstractBackgroundLow resting heart rate (RHR) is a consistent biological correlate of antisocial behaviour (ASB), however potential mechanisms have been largely unexplored. We hypothesise that lower RHR will be associated with higher ASB levels in mid-adolescence and persistence into adulthood, and that these associations will be explained, in part, by sensation seeking and callous-unemotional traits.MethodsASB was assessed repeatedly with young people from ages 15 to 21 years in a population-based birth cohort (ALSPAC). A longitudinal trajectory was derived and showed ASB decreasing across adolescence before stabilising in early adulthood. RHR was recorded at age 12 years, and mediators were assessed at age 14 years.ResultsAfter adjusting for socio-demographic confounders, there was evidence for a total effect of RHR on ASB levels in mid-adolescence [b(95% CI) = −0.08 (−0.14 to −0.02)], reflecting 0.08 more types of antisocial activity in the last year per 10 fewer heart beats per minute. This effect was almost entirely explained through sensation seeking [b(95% CI) = −0.06 (−0.08 to −0.04)]. After additionally adjusting for child and parent-related confounders, all effects weakened; however, there was still evidence of an indirect effect of RHR, via sensation seeking, on ASB levels in mid-adolescence [b(95% CI) = −0.01 (−0.03 to −0.003)]. There was no evidence for a total effect of RHR on ASB levels in early adulthood, and weak evidence of an indirect effect, via sensation seeking [b(95% CI) = −0.01 (−0.01 to −0.00)].ConclusionsLower RHR in childhood was associated with higher ASB levels in mid-adolescence, indirectly via sensation seeking.


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