scholarly journals CNS Diseases: Recent Progress of Nanomedicine in the Treatment of Central Nervous System Diseases (Adv. Therap. 5/2020)

2020 ◽  
Vol 3 (5) ◽  
pp. 2070010
Author(s):  
Leyan Feng ◽  
Heping Wang ◽  
Xue Xue
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Recent Progress ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Cns Diseases

scholarly journals Use of Angong Niuhuang in Treating Central Nervous System Diseases and Related Research

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Yu Guo ◽  
Shaohua Yan ◽  
Lipeng Xu ◽  
Gexin Zhu ◽  
Xiaotong Yu ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chinese Medicine ◽  
Viral Encephalitis ◽  
Current Knowledge ◽  
Pharmacological Effects ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Cns Diseases ◽  
Related Research

In Chinese medicine-based therapeutics, Angong Niuhuang pill (ANP) is one of the three most effective formulas for febrile diseases, and it is also used to treat other diseases. This paper reviews current knowledge regarding the clinical and pharmacological effects of ANP for treating different central nervous system (CNS) diseases to confirm its validity and efficacy. These diseases are like centric fever, coma, stroke, and viral encephalitis. This review reveals that various diseases could be treated using the same agent, which is one of the most important principles of traditional Chinese medicine (TCM). According to the “Same Treatment for Different Diseases” principle, ANP might be efficacious in other CNS diseases.

Roles of glia-derived extracellular vesicles in central nervous system diseases: an update

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hao Sun ◽  
Xiaojuan Su ◽  
Shiping Li ◽  
Dezhi Mu ◽  
Yi Qu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Nucleic Acids ◽  
Extracellular Vesicles ◽  
Extracellular Space ◽  
Cell Communication ◽  
Heterogeneous Group ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Cns Diseases

Abstract Extracellular vesicles (EVs) are a heterogeneous group of cell-derived membranous vesicles secreted by various cells in the extracellular space. Accumulating evidence shows that EVs regulate cell-to-cell communication and signaling in the pathological processes of various diseases by carrying proteins, lipids, and nucleic acids to recipient cells. Glia-derived EVs act as a double-edged sword in the pathogenesis of central nervous system (CNS) diseases. They may be vectors for the spread of diseases or act as effective clearance systems to protect tissues. In this review, we summarize recent studies on glia-derived EVs with a focus on their relationships with CNS diseases.

scholarly journals Mechanisms of Modulation of Ferroptosis and Its Role in Central Nervous System Diseases

2021 ◽  
Vol 12 ◽  
Author(s):  
Qingyun Tan ◽  
Yuying Fang ◽  
Qiong Gu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Coenzyme Q ◽  
Lipid Peroxide ◽  
Regulatory Mechanisms ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Intracellular Iron ◽  
Cns Diseases ◽  
Dependent Pathway

Ferroptosis is a new form of programmed cell death characterized by intracellular iron-dependent accumulation of lipid peroxide and primarily associated with iron metabolism, glutathione-dependent pathway, and coenzyme Q10-dependent pathway. Recent studies demonstrate that ferroptosis is associated with central nervous system (CNS) diseases, such as stroke, Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. This review summarizes the key regulatory mechanisms of ferroptosis and its role in CNS diseases. These updates may provide novel perspective for the development of therapeutical agents against CNS diseases.

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