Palladium-Catalyzed Three-Component Tandem Cyclization Reaction of 2-(2,3-Allenyl)acylacetates, Organic Halides, and Amines: An Effective Protocol for the Synthesis of 4,5-Dihydro-1H-pyrrole Derivatives

2011 ◽  
Vol 353 (10) ◽  
pp. 1676-1682 ◽  
Author(s):  
Jiajia Cheng ◽  
Xuefeng Jiang ◽  
Can Zhu ◽  
Shengming Ma
Keyword(s):  
Cyclization Reaction ◽  
Pyrrole Derivatives ◽  
Organic Halides ◽  
Palladium Catalyzed ◽  
Tandem Cyclization

scholarly journals Palladium-catalyzed three-component tandem cyclization of buta-2,3-dien-1-ol, aryl iodides, and imines: an efficient protocol for the synthesis of oxazolidine derivatives

RSC Advances ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. 7401-7405 ◽  
Author(s):  
Yunlei Hou ◽  
Mingze Qin ◽  
Xiuxiu Yang ◽  
Qi Shen ◽  
Yanfang Zhao ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
Aryl Iodides ◽  
Palladium Catalyzed ◽  
Tandem Cyclization

An efficient three-component tandem cyclization reaction for the synthesis of highly substituted oxazolidines was achieved through the Pd0-catalyzed cyclization of buta-2,3-dien-1-ol with aryl iodides and imines.

Palladium-catalyzed intermolecular tandem cyclization reaction: a highly regioselective synthesis of functionalized 3H-spiro[isobenzofuran-1,3′-isochroman] scaffolds

2017 ◽  
Vol 15 (11) ◽  
pp. 2403-2410 ◽  
Author(s):  
Liang Wang ◽  
Xuehu Li ◽  
Hua Tao ◽  
Xiang Zhou ◽  
Xihong Lu ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
Regioselective Synthesis ◽  
Palladium Catalyzed ◽  
Tandem Cyclization

A highly regioselective synthesis of functionalized 3H-spiro[isobenzofuran-1,3′-isochroman] scaffolds via palladium-catalyzed tandem cyclization.

Synthesis of Novel Bis-pyrazoles via Electrophilic Cyclization

2019 ◽  
Vol 16 (6) ◽  
pp. 511-516
Author(s):  
Adnan Cetin
Keyword(s):  
13C Nmr ◽  
Cyclization Reaction ◽  
Electrophilic Cyclization ◽  
Pyrazole Derivatives ◽  
Spectral Analyses ◽  
Mass Spectral ◽  
Palladium Catalyzed ◽  
Ft Ir ◽  
Reaction Compound

Efficient steps towards the synthesis of novel (phenyl)(1'-aryl-1,5,5'-triphenyl[3,3'-bi-1Hpyrazol]- 4-yl)methanones 4a-e were developed. The procedure starts from 1-(4-benzoyl-1,5-diphenyl- 1H-3-pyrazolyl)-3-phenyl-2-propyn-1-one (2) which was synthesized by a palladium catalyzed crosscoupling reaction. Compound 2 reacted with various hydrazines to give (E)-(phenyl)[1,5-diphenyl-3- [3-phenyl-1-(2-arylhydrazono)-2-propyn-1-yl]-1H-4-pyrazolyl]methanones E-3a-e. The bis-pyrazole derivatives 4a-e were synthesized from electrophilic cyclization reaction of α,β-acetylenic hydrazones E-3a-e and copper(I) iodide. All synthesized compounds were characterized by FT-IR, 1H, 13C NMR and Mass spectral analyses.

scholarly journals Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes: Reaction Scope and Mechanism.

ChemInform ◽  
2005 ◽  
Vol 36 (31) ◽  
Author(s):  
Gangguo Zhu ◽  
Xiaofeng Tong ◽  
Jiang Cheng ◽  
Yanhui Sun ◽  
Dao Li ◽  
...  
Keyword(s):  
Suzuki Coupling ◽  
Palladium Catalyzed ◽  
Tandem Cyclization

Phosphine-Catalyzed Sequential (2+3)/(2+4) Annulation of γ Vinyl Allenoates: Access to the Synthesis of Chromeno[4,3 b]pyrroles

2021 ◽  
Author(s):  
You Huang ◽  
Xiaohu Li
Keyword(s):  
Cyclization Reaction ◽  
Pyrrole Derivatives ◽  
Stereogenic Centers

A phosphine-catalyzed cascade (2+3)/(2+4) cyclization reaction of γ-vinyl allenoates with aldimine ester has been developed to provide a series of chromeno[4,3-b]pyrrole derivatives, which contain three contiguous stereogenic centers. The method...

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