Nanoscale Polymer Metal-Organic Framework Hybrids for Effective Photothermal Therapy of Colon Cancers

2016 ◽  
Vol 28 (42) ◽  
pp. 9320-9325 ◽  
Author(s):  
Weiqi Wang ◽  
Lei Wang ◽  
Yang Li ◽  
Shi Liu ◽  
Zhigang Xie ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Metal Organic Framework ◽  
Colon Cancers ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework

Nanoscaled porphyrinic metal–organic framework for photodynamic/photothermal therapy of tumor

2019 ◽  
Vol 40 (16-17) ◽  
pp. 2204-2210 ◽  
Author(s):  
Shengyan Wang ◽  
Weihua Chen ◽  
Chunhuan Jiang ◽  
Lehui Lu
Keyword(s):  
Photothermal Therapy ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Autonomous atmospheric water seeping MOF matrix

2020 ◽  
Vol 6 (42) ◽  
pp. eabc8605
Author(s):  
G. Yilmaz ◽  
F. L. Meng ◽  
W. Lu ◽  
J. Abed ◽  
C. K. N. Peh ◽  
...  
Keyword(s):  
Fresh Water ◽  
Metal Organic Framework ◽  
Sorption Kinetics ◽  
Solar Irradiation ◽  
Atmospheric Water ◽  
Polymer Metal ◽  
Metal Organic ◽  
Delivery Efficiency ◽  
Organic Framework ◽  
Liquid Delivery

The atmosphere contains an abundance of fresh water, but this resource has yet to be harvested efficiently. To date, passive atmospheric water sorbents have required a desorption step that relies on steady solar irradiation. Since the availability and intensity of solar radiation vary, these limit on-demand desorption and hence the amount of harvestable water. Here, we report a polymer–metal-organic framework that provides simultaneous and uninterrupted sorption and release of atmospheric water. The adaptable nature of the hydro-active polymer, and its hybridization with a metal-organic framework, enables enhanced sorption kinetics, water uptake, and spontaneous water oozing. We demonstrate continuous water delivery for 1440 hours, producing 6 g of fresh water per gram of sorbent at 90% relative humidity (RH) per day without active condensation. This leads to a total liquid delivery efficiency of 95% and an autonomous liquid delivery efficiency of 71%, the record among reported atmospheric water harvesters.

scholarly journals Metal–Organic Framework-Based Chemo-Photothermal Combinational System for Precise, Rapid, and Efficient Antibacterial Therapeutics

Pharmaceutics ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 463 ◽  
Author(s):  
Wu ◽  
Fu ◽  
Zhou ◽  
Wang ◽  
Feng ◽  
...  
Keyword(s):  
Laser Irradiation ◽  
Photothermal Therapy ◽  
Metal Organic Framework ◽  
Global Public Health ◽  
Zeolitic Imidazolate Frameworks ◽  
Porous Carrier ◽  
Metal Organic ◽  
Organic Framework

Rapid increase of antimicrobial resistance has become an urgent threat to global public health. In this research, since photothermal therapy is a potential antibacterial strategy, which is less likely to cause resistance, a metal–organic framework-based chemo-photothermal combinational system was constructed. Zeolitic imidazolate frameworks-8 (ZIF-8), a porous carrier with unique features such as high loading and pH-sensitive degradation, was synthesized, and then encapsulated photothermal agent indocyanine green (ICG). First, ICG with improved stability in ZIF-8 (ZIF-8-ICG) can effectively produce heat in response to NIR laser irradiation for precise, rapid, and efficient photothermal bacterial ablation. Meanwhile, Zn2+ ions released from ZIF-8 can inhibit bacterial growth by increasing the permeability of bacterial cell membrane and further strengthen photothermal therapy efficacy by reducing the heat resistance of bacteria. Study showed that bacteria suffered from significant changes in morphology after treatment with ZIF-8-ICG under laser irradiation. The combinational chemo-hyperthermia therapy of ZIF-8-ICG could thoroughly ablate murine subcutaneous abscess induced by methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a nearly 100% bactericidal ratio. Both in vitro and in vivo safety evaluation confirmed that ZIF-8-ICG was low toxic. Overall, our researches demonstrated that ZIF-8-ICG has great potential to be served as an alternative to antibiotics in combating multidrug-resistant bacterial pathogens.

scholarly journals Metal–Organic Framework/Graphene Quantum Dot Nanoparticles Used for Synergistic Chemo- and Photothermal Therapy

ACS Omega ◽  
2017 ◽  
Vol 2 (3) ◽  
pp. 1249-1258 ◽  
Author(s):  
Zhengfang Tian ◽  
Xianxian Yao ◽  
Kexin Ma ◽  
Xingxing Niu ◽  
Julia Grothe ◽  
...  
Keyword(s):  
Quantum Dot ◽  
Photothermal Therapy ◽  
Metal Organic Framework ◽  
Graphene Quantum Dot ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Surface Engineering of Metal–Organic Framework as pH-/NIR-Responsive Nanocarrier for Imaging-Guided Chemo-Photothermal Therapy

2020 ◽  
Vol Volume 15 ◽  
pp. 3235-3250 ◽  
Author(s):  
Haibin Guo ◽  
Yanqing Xia ◽  
Ke Feng ◽  
Xiaowei Qu ◽  
Cuilian Zhang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Surface Engineering ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework

Biocompatible polymer–metal–organic framework composite patches for cutaneous administration of cosmetic molecules

2016 ◽  
Vol 4 (43) ◽  
pp. 7031-7040 ◽  
Author(s):  
Alfonso García Márquez ◽  
Tania Hidalgo ◽  
Hugo Lana ◽  
Denise Cunha ◽  
María Jose Blanco-Prieto ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Biocompatible Polymer ◽  
Polymer Metal ◽  
Metal Organic ◽  
Cutaneous Administration ◽  
Organic Framework

Caffeine-containing polymer–nanoMOF patches as promising cutaneous formulations.

Polymer–metal–organic framework core–shell framework nanofibers via electrospinning and their gas adsorption activities

RSC Advances ◽  
2016 ◽  
Vol 6 (9) ◽  
pp. 7078-7085 ◽  
Author(s):  
Ming Gao ◽  
Lingwang Zeng ◽  
Jun Nie ◽  
Guiping Ma
Keyword(s):  
Gas Adsorption ◽  
Metal Organic Framework ◽  
Synthesis Method ◽  
Core Shell ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework

In this study, we have fabricated of PAN@ZIF-8 core–shell nanofibers by combining electrospinning techniques and the MOF synthesis method.

scholarly journals Frontispiz: polyMOFs: A Class of Interconvertible Polymer-Metal-Organic-Framework Hybrid Materials

2015 ◽  
Vol 127 (21) ◽  
pp. n/a-n/a
Author(s):  
Zhenjie Zhang ◽  
Ha Thi Hoang Nguyen ◽  
Stephen A. Miller ◽  
Seth M. Cohen
Keyword(s):  
Hybrid Materials ◽  
Metal Organic Framework ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Frontispiece: polyMOFs: A Class of Interconvertible Polymer-Metal-Organic-Framework Hybrid Materials

2015 ◽  
Vol 54 (21) ◽  
pp. n/a-n/a
Author(s):  
Zhenjie Zhang ◽  
Ha Thi Hoang Nguyen ◽  
Stephen A. Miller ◽  
Seth M. Cohen
Keyword(s):  
Hybrid Materials ◽  
Metal Organic Framework ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Water-Based Assembly of Polymer-Metal Organic Framework (MOF) Functional Coatings

2016 ◽  
Vol 4 (2) ◽  
pp. 1600905 ◽  
Author(s):  
Souvik De ◽  
Manjula I. Nandasiri ◽  
Herbert T. Schaef ◽  
Benard Peter McGrail ◽  
Satish K. Nune ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Functional Coatings ◽  
Water Based ◽  
Polymer Metal ◽  
Metal Organic ◽  
Organic Framework
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