scholarly journals Craniofacial Bone‐Tissue Engineering: Heparin‐Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF‐BB to Adipose‐Derived Stem Cells in Tissue Engineered Bone Grafts (Adv. Healthcare Mater. 10/2019)

2019 ◽  
Vol 8 (10) ◽  
pp. 1970042 ◽  
Author(s):  
Alexandra N. Rindone ◽  
Bartlomiej Kachniarz ◽  
Chukwuebuka C. Achebe ◽  
Ryan C. Riddle ◽  
Aine N. O'Sullivan ◽  
...  
2019 ◽  
Vol 8 (10) ◽  
pp. 1801565 ◽  
Author(s):  
Alexandra N. Rindone ◽  
Bartlomiej Kachniarz ◽  
Chukwuebuka C. Achebe ◽  
Ryan C. Riddle ◽  
Aine N. O'Sullivan ◽  
...  

2014 ◽  
Vol 356 (1) ◽  
pp. 97-107 ◽  
Author(s):  
Wei Lu ◽  
Kun Ji ◽  
Jennifer Kirkham ◽  
Yu Yan ◽  
Aldo R. Boccaccini ◽  
...  

2008 ◽  
Vol 84A (1) ◽  
pp. 191-197 ◽  
Author(s):  
Natsuko Kakudo ◽  
Ayuko Shimotsuma ◽  
Shogo Miyake ◽  
Satoshi Kushida ◽  
Kenji Kusumoto

RSC Advances ◽  
2015 ◽  
Vol 5 (67) ◽  
pp. 54551-54562 ◽  
Author(s):  
Gracielle F. Andrade ◽  
Juliana L. Carvalho ◽  
Armando S. C. Júnior ◽  
Alfredo M. Goes ◽  
Edésia M. B. Sousa

Adipose-derived stem cells (ASCs) are currently a point of focus for bone tissue engineering applications.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 902
Author(s):  
Madhumita Patel ◽  
Won-Gun Koh

Composite hydrogels with electrospun nanofibers (NFs) have recently been used to mimic the native extracellular matrix. In this study, composite hydrogels of methacrylated hyaluronic acid containing fragmented polycaprolactone NFs were used for bone tissue engineering. The composite (NF/hydrogel) was crosslinked under ultraviolet (UV) light. The incorporation of fragmented polycaprolactone NFs increased the compression modulus from 1762.5 to 3122.5 Pa. Subsequently, adipose-derived stem cells incorporated into the composite hydrogel exhibited a more stretched and elongated morphology and osteogenic differentiation in the absence of external factors. The mRNA expressions of osteogenic biomarkers, including collagen 1 (Col1), alkaline phosphatase, and runt-related transcription factor 2, were 3–5-fold higher in the composite hydrogel than in the hydrogel alone. In addition, results of the protein expression of Col1 and alizarin red staining confirmed osteogenic differentiation. These findings suggest that our composite hydrogel provides a suitable microenvironment for bone tissue engineering.


2017 ◽  
Vol 2 (2) ◽  
pp. 71-81 ◽  
Author(s):  
Esen Sayin ◽  
Rosti Hama Rashid ◽  
José Carlos Rodríguez-Cabello ◽  
Ahmed Elsheikh ◽  
Erkan Türker Baran ◽  
...  

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