scholarly journals An Injectable Neural Stimulation Electrode Made from an In‐Body Curing Polymer/Metal Composite

2019 ◽  
Vol 8 (23) ◽  
pp. 1900892 ◽  
Author(s):  
James K. Trevathan ◽  
Ian W. Baumgart ◽  
Evan N. Nicolai ◽  
Brian A. Gosink ◽  
Anders J. Asp ◽  
...  
2019 ◽  
Vol 8 (23) ◽  
pp. 1970090 ◽  
Author(s):  
James K. Trevathan ◽  
Ian W. Baumgart ◽  
Evan N. Nicolai ◽  
Brian A. Gosink ◽  
Anders J. Asp ◽  
...  

2019 ◽  
Author(s):  
James K. Trevathan ◽  
Ian W. Baumgart ◽  
Evan N. Nicolai ◽  
Brian A. Gosink ◽  
Anders J. Asp ◽  
...  

AbstractImplanted neural stimulation and recording devices hold vast potential to treat a variety of neurological conditions, but the invasiveness, complexity, and cost of the implantation procedure greatly reduce access to an otherwise promising therapeutic approach. To address this need, we have developed a novel electrode that begins as an uncured, flowable pre-polymer that can be injected around a neuroanatomical target to minimize surgical manipulation. Referred to as the Injectrode, the electrode conforms to target structures forming an electrically conductive interface which is orders of magnitude less stiff than conventional neuromodulation electrodes. To validate the Injectrode, we performed detailed electrochemical and microscopy characterization of its material properties and validated the feasibility of using it to electrically stimulate the nervous system in rats and swine. The silicone-metal-particle composite performed very similarly to pure wire of the same metal (silver) in all measures, including exhibiting a favorable cathodic charge storage capacity (CSCC) and charge injection limits compared to the clinical LivaNova stimulation electrode and silver wire electrodes. By virtue of being simpler than traditional electrode designs, less invasive, and more cost-effective, the Injectrode has the potential to increase the adoption of neuromodulation therapies for existing and new indications.


2011 ◽  
Vol 17 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Mohammad Luqman ◽  
Jang-Woo Lee ◽  
Kwang-Kil Moon ◽  
Young-Tai Yoo

2007 ◽  
Vol 11 (1) ◽  
pp. 88-90
Author(s):  
Yu-yuan Luo ◽  
Jian Jin ◽  
Guo-xian Zhang ◽  
Chao-dong Li

Author(s):  
Muhammad Farid ◽  
Zhao Gang ◽  
Tran Linh Khuong ◽  
Zhuang Zhi Sun ◽  
Naveed Ur Rehman ◽  
...  

Biomimetic is the field of engineering in which biological creatures and their functions are investigated and are used as the basis for the design and manufacturing of machines. Ionic Polymer Metal Composite (IPMC) is a smart material which has demonstrated a meaningful bending and tip force after the application of a low voltage. It is light-weighted, flexible, easily actuated, multi-directional applicable and requires simple manufacturing. Resultantly, IPMC has attracted scientists and researchers to analyze it further and consider it for any industrial and biomimetic applications. Presently, the research on IPMC is bi-directional oriented. A few groups of researchers are busy to find out the causes for the weaknesses of the material and to find out any remedy for them. The second class of scientists is exploring new areas of applications where IPMC material can be used. Although, the application zone of IPMC is ranging from micropumps diaphragms to surgical holding devices, this paper provides an overview of the IPMC application in biomimetic and biomedical field.


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