scholarly journals Enzymatic Micromotors: Enzymatic Micromotors as a Mobile Photosensitizer Platform for Highly Efficient On‐Chip Targeted Antibacteria Photodynamic Therapy (Adv. Funct. Mater. 17/2019)

2019 ◽  
Vol 29 (17) ◽  
pp. 1970112 ◽  
Author(s):  
Dandan Xu ◽  
Chao Zhou ◽  
Chen Zhan ◽  
Yong Wang ◽  
Yongqiang You ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Highly Efficient ◽  
On Chip

Enzymatic Micromotors as a Mobile Photosensitizer Platform for Highly Efficient On‐Chip Targeted Antibacteria Photodynamic Therapy

2019 ◽  
Vol 29 (17) ◽  
pp. 1807727 ◽  
Author(s):  
Dandan Xu ◽  
Chao Zhou ◽  
Chen Zhan ◽  
Yong Wang ◽  
Yongqiang You ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Highly Efficient ◽  
On Chip

A Novel Hybrid Cache Coherence with Global Snooping for Many-core Architectures

2022 ◽  
Vol 27 (1) ◽  
pp. 1-31
Author(s):  
Sri Harsha Gade ◽  
Sujay Deb
Keyword(s):  
Lower Energy ◽  
Cache Coherence ◽  
Network On Chip ◽  
Highly Efficient ◽  
Wireless Links ◽  
Coherence Protocols ◽  
High Area ◽  
On Chip ◽  
Many Core ◽  
Clustered Network

Cache coherence ensures correctness of cached data in multi-core processors. Traditional implementations of existing protocols make them unscalable for many core architectures. While snoopy coherence requires unscalable ordered networks, directory coherence is weighed down by high area and energy overheads. In this work, we propose Wireless-enabled Share-aware Hybrid (WiSH) to provide scalable coherence in many core processors. WiSH implements a novel Snoopy over Directory protocol using on-chip wireless links and hierarchical, clustered Network-on-Chip to achieve low-overhead and highly efficient coherence. A local directory protocol maintains coherence within a cluster of cores, while coherence among such clusters is achieved through global snoopy protocol. The ordered network for global snooping is provided through low-latency and low-energy broadcast wireless links. The overheads are further reduced through share-aware cache segmentation to eliminate coherence for private blocks. Evaluations show that WiSH reduces traffic by and runtime by , while requiring smaller storage and lower energy as compared to existing hierarchical and hybrid coherence protocols. Owing to its modularity, WiSH provides highly efficient and scalable coherence for many core processors.

scholarly journals Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

2020 ◽  
Vol 11 (9) ◽  
pp. 2494-2503 ◽  
Author(s):  
Zheng Zheng ◽  
Haixiang Liu ◽  
Shaodong Zhai ◽  
Haoke Zhang ◽  
Guogang Shan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Molecular Engineering ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation ◽  
Highly Efficient

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

scholarly journals A COF-based nanoplatform for highly efficient cancer diagnosis, photodynamic therapy and prognosis

2020 ◽  
Vol 11 (26) ◽  
pp. 6882-6888 ◽  
Author(s):  
Peng Gao ◽  
Mengzhen Wang ◽  
Yuanyuan Chen ◽  
Wei Pan ◽  
Ping Zhou ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Diagnosis ◽  
Cancer Imaging ◽  
Covalent Organic Framework ◽  
Highly Efficient ◽  
Organic Framework

A covalent organic framework-based nanoplatform has been developed for cancer imaging, photodynamic therapy, and prognosis.

A two-photon AIE fluorophore as a photosensitizer for highly efficient mitochondria-targeted photodynamic therapy

2020 ◽  
Vol 44 (22) ◽  
pp. 9355-9364 ◽  
Author(s):  
Qunshou Kong ◽  
Boxuan Ma ◽  
Tao Yu ◽  
Cheng Hu ◽  
Gaocan Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Two Photon ◽  
Highly Efficient ◽  
Targeted Photodynamic Therapy

Nowadays, photodynamic therapy (PDT) has become an effective method for cancer therapy.

A Highly‐Efficient Type I Photosensitizer with Robust Vascular‐Disruption Activity for Hypoxic‐and‐Metastatic Tumor Specific Photodynamic Therapy

Small ◽  
2020 ◽  
Vol 16 (23) ◽  
pp. 2001059 ◽  
Author(s):  
Dapeng Chen ◽  
Qing Yu ◽  
Xuan Huang ◽  
Hanming Dai ◽  
Tao Luo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Metastatic Tumor ◽  
Type I ◽  
Highly Efficient ◽  
Vascular Disruption ◽  
Efficient Type

ROS-Responsive and active targeted drug delivery based on conjugated polymer nanoparticles for synergistic chemo-/photodynamic therapy

2021 ◽  
Author(s):  
Ziqi Zhang ◽  
Zhuanning Lu ◽  
Qiong Yuan ◽  
Chen Zhang ◽  
Yanli Tang
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Targeted Drug Delivery ◽  
Conjugated Polymer ◽  
Polymer Nanoparticles ◽  
Active Targeting ◽  
Highly Efficient ◽  
Conjugated Polymer Nanoparticles ◽  
Targeted Drug

A biocompatible and ROS-responsive drug delivery nanocarrier iRGD-BDOX@CPNs with active targeting was constructed for highly efficient chemo-/photodynamic (PDT) synergistic therapy.

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