Photoacoustic Imaging Guided Near-Infrared Photothermal Therapy Using Highly Water-Dispersible Single-Walled Carbon Nanohorns as Theranostic Agents

2014 ◽  
Vol 24 (42) ◽  
pp. 6621-6628 ◽  
Author(s):  
Daiqin Chen ◽  
Chao Wang ◽  
Xin Nie ◽  
Shumu Li ◽  
Ruimin Li ◽  
...  
2016 ◽  
Vol 4 (9) ◽  
pp. 1696-1703 ◽  
Author(s):  
Shuo Huang ◽  
Paul Kumar Upputuri ◽  
Hui Liu ◽  
Manojit Pramanik ◽  
Mingfeng Wang

Colloidal nanoparticles of BBT-based narrow-bandgap small molecules as theranostic agents show a strong near-infrared photoacoustic signal and high photothermal conversion efficiency.


2021 ◽  
Vol 4 (2) ◽  
pp. 2019-2029
Author(s):  
Li-Peng Zhang ◽  
Lin Kang ◽  
Xianqiang Li ◽  
Shiyang Liu ◽  
Tianlong Liu ◽  
...  

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  

2020 ◽  
Vol 6 (33) ◽  
pp. eaba3546 ◽  
Author(s):  
Xuan Yi ◽  
Hailin Zhou ◽  
Yu Chao ◽  
Saisai Xiong ◽  
Jing Zhong ◽  
...  

We discovered that attenuated Salmonella after intravenous injection would proliferate within various types of solid tumors but show rapid clearance in normal organs, without rendering notable toxicity. Bacteria-induced inflammation would trigger thrombosis in the infected tumors by destroying tumor blood vessels. Six types of tested tumors would all turn into darkened color with strong near-infrared absorbance, as observed by photoacoustic imaging. Under laser irradiation, those bacterial-infected tumors would be effectively ablated. Because of the immune-stimulation function, such bacteria-based photothermal therapy (PTT) would subsequently trigger antitumor immune responses, which could be further enhanced by immune checkpoint blockade to effectively suppress the growth of abscopal tumors. A robust immune memory effect to reject rechallenged tumors is also observed after bacteria-based PTT. Our work demonstrates that bacteria by themselves could act as a tumor-specific PTT agent to enable photoimmunotherapy cancer therapy to inhibit tumor metastasis and recurrence.


2013 ◽  
Vol 24 (27) ◽  
pp. 275102 ◽  
Author(s):  
Jon Whitney ◽  
Matthew DeWitt ◽  
Bryce M Whited ◽  
William Carswell ◽  
Alex Simon ◽  
...  

Small ◽  
2020 ◽  
Vol 16 (43) ◽  
pp. 2004173 ◽  
Author(s):  
Zhan Zhou ◽  
Bowen Li ◽  
Chuang Shen ◽  
Di Wu ◽  
Huacheng Fan ◽  
...  

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