scholarly journals Foot and Ankle Kinematics in Rheumatoid Arthritis: Influence of Foot and Ankle Joint and Leg Tendon Pathologies

2013 ◽  
Vol 65 (4) ◽  
pp. 503-511 ◽  
Author(s):  
R. Dubbeldam ◽  
H. Baan ◽  
A. V. Nene ◽  
K. W. Drossaers-Bakker ◽  
M. A. F. J. van de Laar ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankle Joint ◽  
Foot And Ankle ◽  
Ankle Kinematics

scholarly journals Postoperative Foot and Ankle Kinematics in Rheumatoid Arthritis

2011 ◽  
Vol 3 (5) ◽  
pp. 233-238 ◽  
Author(s):  
Karl Canseco ◽  
Carolyne Albert ◽  
Jason Long ◽  
Michael Khazzam ◽  
Richard Marks ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Foot And Ankle ◽  
Ankle Kinematics

Foot and ankle joint kinematics in rheumatoid arthritis cannot only be explained by alteration in walking speed

2011 ◽  
Vol 33 (3) ◽  
pp. 390-395 ◽  
Author(s):  
R. Dubbeldam ◽  
A.V. Nene ◽  
J.H. Buurke ◽  
C.G.M. Groothuis-Oudshoorn ◽  
H. Baan ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankle Joint ◽  
Walking Speed ◽  
Joint Kinematics ◽  
Foot And Ankle

scholarly journals Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis

2005 ◽  
Vol 52 (10) ◽  
pp. 3269-3278 ◽  
Author(s):  
István Gál ◽  
Éva Bajnok ◽  
Sándor Szántó ◽  
Bara Sarraj ◽  
Tibor T. Glant ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankle Joint ◽  
Murine Model ◽  
In Situ Analysis ◽  
Leukocyte Trafficking

scholarly journals SAT0047 RISK FACTORS FOR THE POSTOPERATIVE DELAYED WOUND HEALING IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH A BIOLOGICAL AGENT

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 954.3-954
Author(s):  
S. Okita ◽  
H. Ishikawa ◽  
A. Abe ◽  
S. Ito ◽  
A. Murasawa ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Wound Healing ◽  
Retrospective Study ◽  
Nutritional Status ◽  
Disease Activity ◽  
Disease Duration ◽  
Foot And Ankle ◽  
Delayed Wound Healing ◽  
Chugai Pharmaceutical

Background:It has been suggested that perioperative use of biological disease-modifying anti-rheumatic drugs (bDMARDs) in rheumatoid arthritis (RA) patients carries risks for the surgical-site infection and the delayed wound healing (DWH); however, the risk of DWH with perioperative use of bDMARDs has not reached a general consensus.Objectives:This retrospective study aimed to investigate the risk factors associated with DWH after orthopedic surgery in RA patients treated with bDMARDs.Methods:We reviewed medical records of 277 orthopedic procedures for 188 RA patients treated with bDMARDs between from 2014 to 2017 in Niigata Rheumatic Center. As preoperative nutritional status assessment, we evaluated body mass index (BMI), prognostic nutritional index (PNI), and CONtrolling NUTritional status (CONUT). In addition, we evaluated DAS28-CRP, DAS28-ESR, face scale for pain, global health (GH), and Health Assessment Questionnaire-Disability Index (HAQ-DI) to assess the disease activity. Univariate and multivariate logistic regression analyses were performed to evaluate the risk factor for DWH.Results:The major characteristics of the patients in 277 procedures were mean age of 63.2 years old and mean disease duration of 18.2 years. Surgical site were hand and wrist (145 procedures), foot and ankle (76), hip and knee (31), elbow and shoulder (24), and spine (1). Seventy-four patients were treated with tocilizumab, 62 with etanercept, 55 with golimumab, 49 with abatacept, 16 with infliximab, 15 with adalimumab, and 6 with certolizumab. According to nutritional assessment in PNI and CONUT, 63% (n=175) and 47% (n=130) were normal nourished patients, respectively.In 277 procedures, DWH were identified in 24 patients (8.6%). The following variables were significant in the univariate analyses: disease duration (OR 1.053; 95% CI 1.010–1.099; p=0.016), foot and ankle surgery (OR 7.091; 95% CI 2.130–23.603; p=0.001), tocilizumab (OR 0.286; 95% CI 0.093–0.881; p=0.029) (Table 1). These variables were entered into a multivariate model, and it was revealed that pre-operative use of tocilizumab (OR 0.265; 95% CI 0.074–0.953; p=0.042) and procedures in the foot and ankle (OR 6.915; 95% CI 1.914–24.976; p=0.003) were associated with an increased risk of DWH (Table 1).Conclusion:As previous study on tocilizumab described, the current retrospective study suggested that pre-operative use of tocilizumab and procedures in the foot and ankle were risk factors for DWH. Pre-operative disease activity and nutritional status were not independent risk factors for an increase in the prevalence of DWH.References:[1] Momohara S, Hashimoto J, Tsuboi H et al. Analysis of perioperative clinical features and complications after orthopaedic surgery in rheumatoid arthritis patients treated with tocilizumab in a real-world setting: Results from the multicentre tocilizumab in perioperative period (TOPP) study. Modern rheumatology. 2013, 23: 440-9.Disclosure of Interests:Shunji Okita: None declared, Hajime Ishikawa: None declared, Asami Abe: None declared, Satoshi Ito Speakers bureau: Abbvie,Eisai, Akira Murasawa: None declared, Keiichiro Nishida Grant/research support from: K. Nishida has received scholarship donation from CHUGAI PHARMACEUTICAL Co., Eisai Co., Mitsubishi Tanabe Pharma and AbbVie GK., Speakers bureau: K. Nishida has received speaking fees from CHUGAI PHARMACEUTICAL Co., Eli Lilly, Janssen Pharmaceutical K.K., Eisai Co. and AYUMI Pharmaceutical Corporation., Toshifumi Ozaki: None declared

scholarly journals Kinematic changes of the foot and ankle in patients with systemic rheumatoid arthritis and forefoot deformity

2007 ◽  
Vol 25 (3) ◽  
pp. 319-329 ◽  
Author(s):  
Michael Khazzam ◽  
Jason T. Long ◽  
Richard M. Marks ◽  
Gerald F. Harris
Keyword(s):  
Rheumatoid Arthritis ◽  
Foot And Ankle ◽  
Forefoot Deformity

Arteriosclerosis and corticosteroids in rheumatoid arthritis

1974 ◽  
Vol 12 (4) ◽  
pp. 15-16
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankle Joint ◽  
Control Group ◽  
Joint Region ◽  
Tibial Arteries

A recent paper from Denmark1 reports that radiologically visible calcification of tibial arteries in the ankle-joint region was three times as frequent in a group of patients with rheumatoid arthritis who had received corticosteroids for more than six months as in a control group of patients. The author claims that this increased incidence was due to the corticosteroids.

THE FOOT AND ANKLE IN RHEUMATOID ARTHRITIS

Rheumatology ◽  
1995 ◽  
Vol 34 (5) ◽  
pp. 443-448 ◽  
Author(s):  
L. KLENERMAN
Keyword(s):  
Rheumatoid Arthritis ◽  
Foot And Ankle

scholarly journals The small molecule NSM00191 specifically represses the TNF-α/NF-кB axis in foot and ankle rheumatoid arthritis

2018 ◽  
Vol 14 (12) ◽  
pp. 1732-1744 ◽  
Author(s):  
Xiaodong Wen ◽  
Xun Chen ◽  
Xiaojun Liang ◽  
Hongmou Zhao ◽  
Yi Li ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Small Molecule ◽  
Foot And Ankle ◽  
Tnf Α

Foot and Ankle Joint

2001 ◽  
pp. 99-118
Author(s):  
C. E. Bachmann ◽  
G. Gruber ◽  
W. Konermann ◽  
A. Arnold ◽  
G. M. Gruber ◽  
...  
Keyword(s):  
Ankle Joint ◽  
Foot And Ankle
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