scholarly journals Kinematic changes of the foot and ankle in patients with systemic rheumatoid arthritis and forefoot deformity

2007 ◽  
Vol 25 (3) ◽  
pp. 319-329 ◽  
Author(s):  
Michael Khazzam ◽  
Jason T. Long ◽  
Richard M. Marks ◽  
Gerald F. Harris
Keyword(s):  
Rheumatoid Arthritis ◽  
Foot And Ankle ◽  
Forefoot Deformity

scholarly journals SAT0047 RISK FACTORS FOR THE POSTOPERATIVE DELAYED WOUND HEALING IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH A BIOLOGICAL AGENT

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 954.3-954
Author(s):  
S. Okita ◽  
H. Ishikawa ◽  
A. Abe ◽  
S. Ito ◽  
A. Murasawa ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Wound Healing ◽  
Retrospective Study ◽  
Nutritional Status ◽  
Disease Activity ◽  
Disease Duration ◽  
Foot And Ankle ◽  
Delayed Wound Healing ◽  
Chugai Pharmaceutical

Background:It has been suggested that perioperative use of biological disease-modifying anti-rheumatic drugs (bDMARDs) in rheumatoid arthritis (RA) patients carries risks for the surgical-site infection and the delayed wound healing (DWH); however, the risk of DWH with perioperative use of bDMARDs has not reached a general consensus.Objectives:This retrospective study aimed to investigate the risk factors associated with DWH after orthopedic surgery in RA patients treated with bDMARDs.Methods:We reviewed medical records of 277 orthopedic procedures for 188 RA patients treated with bDMARDs between from 2014 to 2017 in Niigata Rheumatic Center. As preoperative nutritional status assessment, we evaluated body mass index (BMI), prognostic nutritional index (PNI), and CONtrolling NUTritional status (CONUT). In addition, we evaluated DAS28-CRP, DAS28-ESR, face scale for pain, global health (GH), and Health Assessment Questionnaire-Disability Index (HAQ-DI) to assess the disease activity. Univariate and multivariate logistic regression analyses were performed to evaluate the risk factor for DWH.Results:The major characteristics of the patients in 277 procedures were mean age of 63.2 years old and mean disease duration of 18.2 years. Surgical site were hand and wrist (145 procedures), foot and ankle (76), hip and knee (31), elbow and shoulder (24), and spine (1). Seventy-four patients were treated with tocilizumab, 62 with etanercept, 55 with golimumab, 49 with abatacept, 16 with infliximab, 15 with adalimumab, and 6 with certolizumab. According to nutritional assessment in PNI and CONUT, 63% (n=175) and 47% (n=130) were normal nourished patients, respectively.In 277 procedures, DWH were identified in 24 patients (8.6%). The following variables were significant in the univariate analyses: disease duration (OR 1.053; 95% CI 1.010–1.099; p=0.016), foot and ankle surgery (OR 7.091; 95% CI 2.130–23.603; p=0.001), tocilizumab (OR 0.286; 95% CI 0.093–0.881; p=0.029) (Table 1). These variables were entered into a multivariate model, and it was revealed that pre-operative use of tocilizumab (OR 0.265; 95% CI 0.074–0.953; p=0.042) and procedures in the foot and ankle (OR 6.915; 95% CI 1.914–24.976; p=0.003) were associated with an increased risk of DWH (Table 1).Conclusion:As previous study on tocilizumab described, the current retrospective study suggested that pre-operative use of tocilizumab and procedures in the foot and ankle were risk factors for DWH. Pre-operative disease activity and nutritional status were not independent risk factors for an increase in the prevalence of DWH.References:[1] Momohara S, Hashimoto J, Tsuboi H et al. Analysis of perioperative clinical features and complications after orthopaedic surgery in rheumatoid arthritis patients treated with tocilizumab in a real-world setting: Results from the multicentre tocilizumab in perioperative period (TOPP) study. Modern rheumatology. 2013, 23: 440-9.Disclosure of Interests:Shunji Okita: None declared, Hajime Ishikawa: None declared, Asami Abe: None declared, Satoshi Ito Speakers bureau: Abbvie,Eisai, Akira Murasawa: None declared, Keiichiro Nishida Grant/research support from: K. Nishida has received scholarship donation from CHUGAI PHARMACEUTICAL Co., Eisai Co., Mitsubishi Tanabe Pharma and AbbVie GK., Speakers bureau: K. Nishida has received speaking fees from CHUGAI PHARMACEUTICAL Co., Eli Lilly, Janssen Pharmaceutical K.K., Eisai Co. and AYUMI Pharmaceutical Corporation., Toshifumi Ozaki: None declared

THE FOOT AND ANKLE IN RHEUMATOID ARTHRITIS

Rheumatology ◽  
1995 ◽  
Vol 34 (5) ◽  
pp. 443-448 ◽  
Author(s):  
L. KLENERMAN
Keyword(s):  
Rheumatoid Arthritis ◽  
Foot And Ankle

scholarly journals The small molecule NSM00191 specifically represses the TNF-α/NF-кB axis in foot and ankle rheumatoid arthritis

2018 ◽  
Vol 14 (12) ◽  
pp. 1732-1744 ◽  
Author(s):  
Xiaodong Wen ◽  
Xun Chen ◽  
Xiaojun Liang ◽  
Hongmou Zhao ◽  
Yi Li ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Small Molecule ◽  
Foot And Ankle ◽  
Tnf Α

Foot and ankle

2013 ◽  
pp. 1337-1342
Author(s):  
Anthony C. Redmond ◽  
Philip S. Helliwell
Keyword(s):  
Rheumatoid Arthritis ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Plantar Fasciitis ◽  
Foot And Ankle ◽  
Hypermobility Syndrome ◽  
Local Conditions ◽  
The Subject

Foot and ankle problems have been the subject of major advances in the rheumatology in recent years. This chapter reviews the anatomy of the foot and covers the manifestations of foot pathology for the major conditions: rheumatoid arthritis, osteoarthritis, spondyloarthritis, connective tissue disease, crystal diseases, and miscellaneous conditions including hypermobility syndrome. Relevant local conditions including plantar fasciitis, tendinopathy, and neuroma are addressed separately. The principles of assessing and treating the foot and ankle in rheumatology are covered, along with the relevant specific approaches best suited to dealing with problems associated with the major conditions.

scholarly journals AB0330 RELATIONSHIP BETWEEN FOREFOOT SYNOVITIS IN RHEUMATOID ARTHRITIS AND WORSENING FOREFOOT DEFORMITY

2019 ◽  
Author(s):  
Takeshi Kashiwagura ◽  
Moto Kobayashi ◽  
Masakazu Urayama ◽  
Natsuo Konishi ◽  
Hiroki Itoh ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Forefoot Deformity

scholarly journals Systematic review of the psychometric properties of patient-reported outcome measures for rheumatoid arthritis in the foot and ankle

2019 ◽  
Vol 33 (11) ◽  
pp. 1788-1799 ◽  
Author(s):  
Ana Belen Ortega-Avila ◽  
Laura Ramos-Petersen ◽  
Pablo Cervera-Garvi ◽  
Christopher J Nester ◽  
José Miguel Morales-Asencio ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Psychometric Properties ◽  
Outcome Measures ◽  
Methodological Quality ◽  
Measurement Properties ◽  
Foot And Ankle ◽  
Inclusion Criteria ◽  
Patient Reported

Objective: To identify self-reported outcome measures specific to the foot and ankle in patients with rheumatoid arthritis and to investigate the methodological quality and psychometric properties of these measures. Method: A systematic review focusing on patients with rheumatoid arthritis. Setting: The search was conducted in the PubMed, SCOPUS, CINAHL, PEDro and Google Scholar databases, based on the following inclusion criteria: population (with rheumatoid arthritis) > 18 years; psychometric or clinimetric validation studies of patient-reported outcomes specific to the foot and ankle, in different languages, with no time limit. Two of the present authors independently assessed the quality of the studies located and extracted the relevant data. Terwee’s criteria and the COSMIN checklist were employed to ensure adequate methodological quality. Results: Of the initial 431 studies considered, 14 met the inclusion criteria, representing 7,793 patients (56.8 years). These instruments were grouped into three dimensions (pain, perceived health status and quality of life and disability). The time to complete any of the PROMs varies around 15 minutes. PROMs criterias with the worst scores by COSMIN, 92.85% and 85.71% were criterion validity, measurement error, internal consistency and responsiveness. 28.57% of PROMs were compared with the measurement properties. Conclusion: the Self-Reported Foot and Ankle Score achieved the highest number of positive criteria (according to Terwee and COSMIN), and is currently the most appropriate for patients with Rheumatoid arthritis.

Rheumatoid Nodules and Postoperative Complications

2003 ◽  
Vol 24 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Christopher Bibbo ◽  
Robert B. Anderson ◽  
W. Hodges Davis ◽  
Jim Norton
Keyword(s):  
Rheumatoid Arthritis ◽  
Postoperative Outcome ◽  
Infectious Complications ◽  
Chemotherapeutic Agents ◽  
Operative Procedures ◽  
Rheumatoid Nodule ◽  
Foot And Ankle ◽  
Statistical Association ◽  
Rheumatoid Nodules ◽  
Ankle Surgery

The records of 104 patients who underwent reconstructive foot and ankle surgery for deformities secondary to rheumatoid arthritis were reviewed. The use of rheumatoid chemotherapeutic agents, age, sex, rheumatoid nodule status, and the number of concurrent surgical procedures performed was analyzed to determine any association with the postoperative outcome for wound healing and infectious complications. The 104 patients, ranging in age from 23 to 83 years, underwent 725 operative procedures. An overall 32% complication rate was recorded. Analysis of five specific rheumatoid chemotherapeutic agents (NSAIDs, steroids, methotrexate, hydroxychloroquine, gold), age, sex, number of operative procedures performed, and presence of rheumatoid nodules, either alone or in combination, failed to prove a statistical association with either a healing or infectious postoperative complication.

Sign in / Sign up

Export Citation Format

Share Document