Celecoxib Decreases Gcf Prostaglandin E2 Levels in Chronic Periodontitis Patients

Prostaglandin E2 (PGE2) is a key mediator associated with periodontal bone loss. We recently demonstrated (Yen, et al, J Periodontology 79:104, 2008) that adjunctive use of Celecoxib (a COX-2 selective inhibitor) in conjunction with Scaling and Root Planning (SRP) resulted in significant reduction in Pocket Depth (PD) and gain in Clinical Attachment (CAL) in Chronic Periodontitis (CP) patients.

Analysis of the Indigenous and Pathogenic Microbiota in Bone Sequestration due to Osteonecrosis of the jaws by Bisphosphonates (MRONJ)

The American Surgery of Bone Mineral Research (ASBMR) defined MRONJ as “necrotic bone area exposed to the oral environment with more than eight weeks of permanence, in the presence of chronic treatment with BPs, in the absence of radiation therapy to the head and neck in 2007.

Implant Overdenture - A Review to Highlight the Concept

Implant overdenture treatments cover one of the possible treatment solutions to the patients have some teeth/ roots retained, in patients completely edentulous or wearing conventional overdentures.