Reproductive system of women with acromegaly

192 patients with acromegaly were examined. Their reproductive disorders were found to be a result of the suppressed synthesis of gonadotropin hormones due to the tumor compression of the adenohypophysis, due to blocking effect of hyperprolactinemia on the gonadotropic function or as a result of the direct impact of insulin-like growth factor-I stimulating hyperplastic processes in target organs, such as ovaries, the glandular epithelium of the breast and myometrium. The structure of reproductive disorders in patients with acromegaly includes menstrual disturbances, infertility, early menopause and hyperplastic processes. Close management of the reproductive system, early detection of neoplasia and correction of the existing disorders are highly required during therapy for acromegaly.

Hyperprolactinemia and pregnancy: the basic achievements and unresolved problems

From the sociopolitical and economic points of view the child-bearing is very actual problem for Russia. Demographers believe that our population can decrease twice in 25-30 years, because of medical factors partly.Every fifth family in Russia is infertility now. Female infertility is caused by hyperprolactinemia in 25-40 % of all cases. Rate of hyperprolactinemia at the infertile men reaches 30 %. However hyperprolactinemia is the cause of infertility which can be successfully cured now.

Planning of pregnancy in women with diabetes

Pregnancy is a complex metabolic state, which includes dramatic changes in hormone secretion, amid growing demand for energy-rich compounds necessary for growth and development of the fetus. Women with diagnosed diabetes is always a greater risk of obstetric complications, which can be prevented by knowing the risk factors for diabetes, the criteria for early diagnosis, an algorithm of pregnancy, careful management of the postpartum period.