Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery
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Published By Springer Singapore

9789811387180, 9789811387197

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Interrogating Regulatory Mechanisms in Signaling Proteins by Allosteric Inhibitors and Activators: A Dynamic View Through the Lens of Residue Interaction Networks

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_9 ◽

2019 ◽

pp. 187-223 ◽

Cited By ~ 1

Author(s):

Lindy Astl ◽

Amanda Tse ◽

Gennady M. Verkhivker

Keyword(s):

Interaction Networks ◽

Regulatory Mechanisms ◽

Signaling Proteins ◽

Allosteric Inhibitors ◽

Residue Interaction ◽

Dynamic View

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Dynamic Protein Allosteric Regulation and Disease

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_2 ◽

2019 ◽

pp. 25-43

Author(s):

Ruth Nussinov ◽

Chung-Jung Tsai ◽

Hyunbum Jang

Keyword(s):

Allosteric Regulation

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Allosteric Modulators of Protein–Protein Interactions (PPIs)

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_13 ◽

2019 ◽

pp. 313-334 ◽

Cited By ~ 5

Author(s):

Duan Ni ◽

Na Liu ◽

Chunquan Sheng

Keyword(s):

Protein Interactions ◽

Allosteric Modulators ◽

Protein Protein Interactions

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Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_12 ◽

2019 ◽

pp. 279-311 ◽

Cited By ~ 2

Author(s):

Alejandro E. Leroux ◽

Lissy Z. F. Gross ◽

Mariana Sacerdoti ◽

Ricardo M. Biondi

Keyword(s):

Protein Kinases ◽

Allosteric Regulation ◽

Pi3 Kinase

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Allosteric Small-Molecule Serine/Threonine Kinase Inhibitors

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_11 ◽

2019 ◽

pp. 253-278 ◽

Cited By ~ 3

Author(s):

Resmi C. Panicker ◽

Souvik Chattopadhaya ◽

Anthony G. Coyne ◽

Rajavel Srinivasan

Keyword(s):

Small Molecule ◽

Kinase Inhibitors ◽

Serine Threonine Kinase ◽

Threonine Kinase

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Advances in NMR Methods to Identify Allosteric Sites and Allosteric Ligands

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_8 ◽

2019 ◽

pp. 171-186

Author(s):

Hazem Abdelkarim ◽

Ben Hitchinson ◽

Avik Banerjee ◽

Vadim Gaponenko

Keyword(s):

Allosteric Sites ◽

Nmr Methods

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Characteristics of Allosteric Proteins, Sites, and Modulators

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_6 ◽

2019 ◽

pp. 107-139

Author(s):

Xinheng He ◽

Duan Ni ◽

Shaoyong Lu ◽

Jian Zhang

Keyword(s):

Allosteric Proteins

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Engineering Allostery into Proteins

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_15 ◽

2019 ◽

pp. 359-384 ◽

Cited By ~ 3

Author(s):

Scott D. Gorman ◽

Rebecca N. D’Amico ◽

Dennis S. Winston ◽

David D. Boehr

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Advances in the Computational Identification of Allosteric Sites and Pathways in Proteins

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_7 ◽

2019 ◽

pp. 141-169 ◽

Cited By ~ 4

Author(s):

Xavier Daura

Keyword(s):

Allosteric Sites ◽

Computational Identification

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GPCR Allosteric Modulator Discovery

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery ◽

10.1007/978-981-13-8719-7_10 ◽

2019 ◽

pp. 225-251 ◽

Cited By ~ 5

Author(s):

Yiran Wu ◽

Jiahui Tong ◽

Kang Ding ◽

Qingtong Zhou ◽

Suwen Zhao

Keyword(s):

Allosteric Modulator

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Advances in Experimental Medicine and Biology - Protein Allostery in Drug DiscoveryLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Springer Singapore

Interrogating Regulatory Mechanisms in Signaling Proteins by Allosteric Inhibitors and Activators: A Dynamic View Through the Lens of Residue Interaction Networks

Dynamic Protein Allosteric Regulation and Disease

Allosteric Modulators of Protein–Protein Interactions (PPIs)

Allosteric Regulation of Protein Kinases Downstream of PI3-Kinase Signalling

Allosteric Small-Molecule Serine/Threonine Kinase Inhibitors

Advances in NMR Methods to Identify Allosteric Sites and Allosteric Ligands

Characteristics of Allosteric Proteins, Sites, and Modulators

Engineering Allostery into Proteins

Advances in the Computational Identification of Allosteric Sites and Pathways in Proteins

GPCR Allosteric Modulator Discovery

Advances in Experimental Medicine and Biology - Protein Allostery in Drug Discovery
Latest Publications