Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism
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Published By Humana Press

9781627037570, 9781627037587

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Enzyme Kinetics, Inhibition, and Regioselectivity of Aldehyde Oxidase

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_9 ◽

2014 ◽

pp. 167-186 ◽

Cited By ~ 10

Author(s):

John T. Barr ◽

Kanika Choughule ◽

Jeffrey P. Jones

Keyword(s):

Enzyme Kinetics ◽

Aldehyde Oxidase

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Principles and Experimental Considerations for In Vitro Transporter Interaction Assays

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_12 ◽

2014 ◽

pp. 229-252 ◽

Cited By ~ 4

Author(s):

Sid Bhoopathy ◽

Chris Bode ◽

Vatsala Naageshwaran ◽

Erica A. Weiskircher-Hildebrandt ◽

Ismael J. Hidalgo

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Rationalizing Underprediction of Drug Clearance from Enzyme and Transporter Kinetic Data: From In Vitro Tools to Mechanistic Modeling

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_13 ◽

2014 ◽

pp. 255-288 ◽

Cited By ~ 13

Author(s):

Aleksandra Galetin

Keyword(s):

Kinetic Data ◽

Drug Clearance ◽

Mechanistic Modeling

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Multienzyme Kinetics and Sequential Metabolism

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_6 ◽

2014 ◽

pp. 93-118 ◽

Cited By ~ 7

Author(s):

Larry C. Wienkers ◽

Brooke Rock

Keyword(s):

Sequential Metabolism

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Case Study 3. Application of Basic Enzyme Kinetics to Metabolism Studies: Real-Life Examples

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_20 ◽

2014 ◽

pp. 441-460

Author(s):

Yongmei Li ◽

Michelle McCabe ◽

Lalitha Podila ◽

Timothy S. Tracy ◽

Donald J. Tweedie

Keyword(s):

Enzyme Kinetics ◽

Real Life

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A Structural Model for the Mass Action Kinetic Analysis of P-gp Mediated Transport Through Confluent Cell Monolayers

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_14 ◽

2014 ◽

pp. 289-316 ◽

Cited By ~ 4

Author(s):

Joe Bentz ◽

Harma Ellens

Keyword(s):

Kinetic Analysis ◽

Structural Model ◽

Mass Action ◽

Cell Monolayers ◽

Mass Action Kinetic ◽

Confluent Cell

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Case Study 6. Transporter Case Studies: In Vitro Solutions for Translatable Outcomes

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_23 ◽

2014 ◽

pp. 485-511

Author(s):

Sid Bhoopathy ◽

Chris Bode ◽

Vatsala Naageshwaran ◽

Erica A. Weiskircher-Hildebrandt ◽

Ismael J. Hidalgo

Keyword(s):

Case Studies

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Case Study 2. Practical Analytical Considerations for Conducting In Vitro Enzyme Kinetic Studies

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_19 ◽

2014 ◽

pp. 431-439 ◽

Cited By ~ 1

Author(s):

Upendra A. Argikar ◽

Swati Nagar

Keyword(s):

Kinetic Studies ◽

Enzyme Kinetic

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Variability in Human In Vitro Enzyme Kinetics

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_16 ◽

2014 ◽

pp. 337-362 ◽

Cited By ~ 1

Author(s):

Ying-Hong Wang ◽

Christopher R. Gibson

Keyword(s):

Enzyme Kinetics

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Irreversible Enzyme Inhibition Kinetics and Drug–Drug Interactions

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism ◽

10.1007/978-1-62703-758-7_5 ◽

2014 ◽

pp. 57-91 ◽

Cited By ~ 12

Author(s):

Michael Mohutsky ◽

Stephen D. Hall

Keyword(s):

Drug Interactions ◽

Enzyme Inhibition ◽

Inhibition Kinetics ◽

Enzyme Inhibition Kinetics

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Methods in Molecular Biology - Enzyme Kinetics in Drug MetabolismLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Humana Press

Enzyme Kinetics, Inhibition, and Regioselectivity of Aldehyde Oxidase

Principles and Experimental Considerations for In Vitro Transporter Interaction Assays

Rationalizing Underprediction of Drug Clearance from Enzyme and Transporter Kinetic Data: From In Vitro Tools to Mechanistic Modeling

Multienzyme Kinetics and Sequential Metabolism

Case Study 3. Application of Basic Enzyme Kinetics to Metabolism Studies: Real-Life Examples

A Structural Model for the Mass Action Kinetic Analysis of P-gp Mediated Transport Through Confluent Cell Monolayers

Case Study 6. Transporter Case Studies: In Vitro Solutions for Translatable Outcomes

Case Study 2. Practical Analytical Considerations for Conducting In Vitro Enzyme Kinetic Studies

Variability in Human In Vitro Enzyme Kinetics

Irreversible Enzyme Inhibition Kinetics and Drug–Drug Interactions

Methods in Molecular Biology - Enzyme Kinetics in Drug Metabolism
Latest Publications