The authors argue that dialogical philosophy, and particularly the work of the Bakhtin circle, offers psychology a way to conceptualize and study human experience such that the notion of psyche is preserved and enriched. The authors first introduce the work of the Bakhtin circle and then briefly outline some of the most influential theories of self and psyche. The implications of dialogism for theories of the self are then discussed, focusing on six basic principles of dialogical thought – namely, the principles of relationality, dynamism, semiotic mediation, alterity, dialogicality, and contextuality. Together, these principles imply a notion of psyche that is neither an isolated homunculus nor a disembodied discourse, but is, rather, a temporally unique, agentive enactment that is sustained within, rather than against, the tensions between individual and social, material and psychological, multiple and unified, stable and dynamic. The authors also discuss what this dialogical conception of psyche implies for research, arguing first that dynamic relations, rather than static entities, are the proper unit of psychological study and, second, that a dialogical research epistemology must conceive of truth as a multi-voiced event, rather than as a singular representation of fact. Finally, the authors introduce this special issue and outline the other contributions.